| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 388 |
Name | RHOB |
Synonym | ARH6|ARHB|MST081|MSTP081|RHOH6;ras homolog family member B;RHOB;ras homolog family member B |
Definition | Aplysia RAS-related homolog 6|h6|oncogene RHO H6|ras homolog gene family, member B|rho cDNA clone 6|rho-related GTP-binding protein RhoB |
Position | 2p24 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PH | "RhoB mediates adaptational changes to acute hypoxia in the vasculature, but its continual activation by chronic hypoxia can accentuate vascular remodeling to promote development of pulmonary hypertension." |
PH | "RhoB mediates adaptational changes to acute hypoxia in the vasculature, but its continual activation by chronic hypoxia can accentuate vascular remodeling to promote development of pulmonary hypertension." |
| More detail of all Human literatures about RHOB | |
|
Pathways and Diseases |
|
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Axon guidance mediated by Slit/Robo;PANTHER;P00008 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Signaling by Rho GTPases;Reactome;REACT:11044 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | Ras Pathway;PANTHER;P04393 |
Pathway | Cytoskeletal regulation by Rho GTPase;PANTHER;P00016 |
Disease | Cancer;FunDO |
Disease | Polyarthritis;FunDO |
|
External Links |
|
Links to Entrez Gene | 388 |
Links to all GeneRIF Items | 388 |
Links to iHOP | 388 |
|
Sequence Information |
|
Nucleotide Sequence |
>388 : length: 591 atggcggccatccgcaagaagctggtggtggtgggcgacggcgcgtgtggcaagacgtgc ctgctgatcgtgttcagtaaggacgagttccccgaggtgtacgtgcccaccgtcttcgag aactatgtggccgacattgaggtggacggcaagcaggtggagctggcgctgtgggacacg gcgggccaggaggactacgaccgcctgcggccgctctcctacccggacaccgacgtcatt ctcatgtgcttctcggtggacagcccggactcgctggagaacatccccgagaagtgggtc cccgaggtgaagcacttctgtcccaatgtgcccatcatcctggtggccaacaaaaaagac ctgcgcagcgacgagcatgtccgcacagagctggcccgcatgaagcaggaacccgtgcgc acggatgacggccgcgccatggccgtgcgcatccaagcctacgactacctcgagtgctct gccaagaccaaggaaggcgtgcgcgaggtcttcgagacggccacgcgcgccgcgctgcag aagcgctacggctcccagaacggctgcatcaactgctgcaaggtgctatga |
Protein Sequence |
>388 : length: 196 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ KRYGSQNGCINCCKVL |