Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

388585

Name

HES5

Synonym

bHLHb38;hairy and enhancer of split 5 (Drosophila);HES5;hairy and enhancer of split 5 (Drosophila)

Definition

class B basic helix-loop-helix protein 38|transcription factor HES-5

Position

1p36.32

Gene Type

protein-coding

PAH Type

Description

PAH

Notch3 signaling promotes the development of pulmonary arterial hypertension.
More detail of all Human literatures about HES5

Pathways and Diseases

Pathway

Notch signaling pathway;KEGG PATHWAY;hsa04330

Pathway

Notch signaling pathway;PANTHER;P00045

Pathway

CDC42 signaling events;PID Curated;200057

Disease

Squamous cell cancer;FunDO

Disease

Cervical cancer;FunDO

External Links

Links to Entrez Gene

388585

Links to all GeneRIF Items

388585

Links to iHOP

388585

Sequence Information

Nucleotide Sequence

>388585 : length: 501
atggcccccagcactgtggccgtggagctgctcagccccaaagagaaaaaccgactgcgg
aagccggtggtggagaagatgcgccgcgaccgcatcaacagcagcatcgagcagctgaag
ctgctgctggagcaggagttcgcgcggcaccagcccaactccaagctggagaaggccgac
atcctggagatggctgtcagctacctgaagcacagcaaagccttcgtcgccgccgccggc
cccaagagcctgcaccaggactacagcgaaggctactcgtggtgcctgcaggaggccgtg
cagttcctgacgctccacgccgccagcgacacgcagatgaagctgctgtaccacttccag
cggcccccggccgcgcccgccgcgcccgccaaggagcccaaggcgccgggcgccgcgccc
ccgcccgcgctctccgccaaggccaccgccgccgccgccgccgcgcaccagcccgcctgc
ggcctctggcggccctggtga

Protein Sequence

>388585 : length: 166
MAPSTVAVELLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKAD
ILEMAVSYLKHSKAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHFQ
RPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPACGLWRPW



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