| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 4485 |
Name | MST1 |
Synonym | D3F15S2|DNF15S2|HGFL|MSP|NF15S2;macrophage stimulating 1 (hepatocyte growth factor-like);MST1;macrophage stimulating 1 (hepatocyte growth factor-like) |
Definition | hepatocyte growth factor-like protein|hepatocyte growth factor-like protein homolog|macrophage-stimulating protein |
Position | 3p21 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically." |
| More detail of all Human literatures about MST1 | |
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Pathways and Diseases |
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Pathway | a6b1 and a6b4 Integrin signaling;PID Curated;200162 |
Pathway | FoxO family signaling;PID Curated;200091 |
Disease | IMMUNE;GAD |
Disease | Crohn's disease;GAD |
Disease | Ulcerative colitis;NHGRI |
Disease | Crohn's disease;NHGRI |
Disease | Endometriosis;FunDO |
Disease | ulcerative colitis;GAD |
Disease | Breast cancer;FunDO |
Disease | Neoplasm metastasis;FunDO |
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External Links |
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Links to Entrez Gene | 4485 |
Links to all GeneRIF Items | 4485 |
Links to iHOP | 4485 |
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Sequence Information |
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Nucleotide Sequence |
>4485 : length: 2178 atggggctgtggtgggtcacagtgcagcctccagccagaaggatggggtggctcccactc ctgctgcttctgactcaatgcttaggggtccctgggcagcgctcgccattgaatgacttc caagtgctccggggcacagagctacagcacctgctacatgcggtggtgcccgggccttgg caggaggatgtggcagatgctgaagagtgtgctggtcgctgtgggcccttaatggactgc cgggccttccactacaacgtgagcagccatggttgccaactgctgccatggactcaacac tcgccccacacgaggctgcggcgttctgggcgctgtgacctcttccagaagaaagactac gtacggacctgcatcatgaacaatggggttgggtaccggggcaccatggccacgaccgtg ggtggcctgccctgccaggcttggagccacaagttcccaaatgatcacaagtacacgccc actctccggaatggcctggaagagaacttctgccgtaaccctgatggcgaccccggaggt ccttggtgctacacaacagaccctgctgtgcgcttccagagctgcggcatcaaatcctgc cgggaggccgcgtgtgtctggtgcaatggcgaggaataccgcggcgcggtagaccgcacg gagtcagggcgcgagtgccagcgctgggatcttcagcacccgcaccagcaccccttcgag ccgggcaagttcctcgaccaaggtctggacgacaactattgccggaatcctgacggctcc gagcggccatggtgctacactacggatccgcagatcgagcgagagttctgtgacctcccc cgctgcgggtccgaggcacagccccgccaagaggccacaactgtcagctgcttccgcggg aagggtgagggctaccggggcacagccaataccaccactgcgggcgtaccttgccagcgt tgggacgcgcaaatcccgcatcagcaccgatttacgccagaaaaatacgcgtgcaaagac cttcgggagaacttctgccggaaccccgacggctcagaggcgccctggtgcttcacactg cggcccggcatgcgcgcggccttttgctaccagatccggcgttgtacagacgacgtgcgg ccccaggactgctaccacggcgcaggggagcagtaccgcggcacggtcagcaagacccgc aagggtgtccagtgccagcgctggtccgctgagacgccgcacaagccgcagttcacgttt acctccgaaccgcatgcacaactggaggagaacttctgccggaacccagatggggatagc catgggccctggtgctacacgatggacccaaggaccccattcgactactgtgccctgcga cgctgcgctgatgaccagccgccatcaatcctggaccccccagaccaggtgcagtttgag aagtgtggcaagagggtggatcggctggatcagcggcgttccaagctgcgcgtggttggg ggccatccgggcaactcaccctggacagtcagcttgcggaatcggcagggccagcatttc tgcggggggtctctagtgaaggagcagtggatactgactgcccggcagtgcttctcctcc tgccatatgcctctcacgggctatgaggtatggttgggcaccctgttccagaacccacag catggagagccaagcctacagcgggtcccagtagccaagatggtgtgtgggccctcaggc tcccagcttgtcctgctcaagctggagagatctgtgaccctgaaccagcgtgtggccctg atctgcctgccccctgaatggtatgtggtgcctccagggaccaagtgtgagattgcaggc tggggtgagaccaaaggtacgggtaatgacacagtcctaaatgtggccttgctgaatgtc atctccaaccaggagtgtaacatcaagcaccgaggacgtgtgcgggagagtgagatgtgc actgagggactgttggcccctgtgggggcctgtgagggtgactacgggggcccacttgcc tgctttacccacaactgctgggtcctggaaggaattataatccccaaccgagtatgcgca aggtcccgctggccagctgtcttcacgcgtgtctctgtgtttgtggactggattcacaag gtcatgagactgggttag |
Protein Sequence |
>4485 : length: 725 MGLWWVTVQPPARRMGWLPLLLLLTQCLGVPGQRSPLNDFQVLRGTELQHLLHAVVPGPW QEDVADAEECAGRCGPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLFQKKDY VRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLRNGLEENFCRNPDGDPGG PWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFE PGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRG KGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTL RPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTF TSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADDQPPSILDPPDQVQFE KCGKRVDRLDQRRSKLRVVGGHPGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSS CHMPLTGYEVWLGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQLVLLKLERSVTLNQRVAL ICLPPEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKHRGRVRESEMC TEGLLAPVGACEGDYGGPLACFTHNCWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHK VMRLG |