Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5037

Name

PEBP1

Synonym

HCNP|HCNPpp|PBP|PEBP|PEBP-1|RKIP;phosphatidylethanolamine binding protein 1;PEBP1;phosphatidylethanolamine binding protein 1

Definition

Raf kinase inhibitory protein|hippocampal cholinergic neurostimulating peptide|neuropolypeptide h3|phosphatidylethanolamine-binding protein 1|prostatic binding protein|prostatic-binding protein|raf kinase inhibitor protein

Position

12q24.23

Gene Type

protein-coding

PAH Type

Description

HPH

Mice lacking the Raf-1 kinase inhibitor protein exhibit exaggerated hypoxia-induced pulmonary hypertension.
More detail of all Mouse literatures about PEBP1

Pathways and Diseases

Pathway

signal transduction through il1r;PID BioCarta;100132

Pathway

Aurora B signaling;PID Curated;200010

Pathway

EGF receptor signaling pathway;PANTHER;P00018

Pathway

ErbB1 downstream signaling;PID Curated;200113

Pathway

FGF signaling pathway;PANTHER;P00021

Disease

Cancer;FunDO

External Links

Links to Entrez Gene

5037

Links to all GeneRIF Items

5037

Links to iHOP

5037

Sequence Information

Nucleotide Sequence

>5037 : length: 564
atgccggtggacctcagcaagtggtccgggcccttgagcctgcaagaagtggacgagcag
ccgcagcacccgctgcatgtcacctacgccggggcggcggtggacgagctgggcaaagtg
ctgacgcccacccaggttaagaatagacccaccagcatttcgtgggatggtcttgattca
gggaagctctacaccttggtcctgacagacccggatgctcccagcaggaaggatcccaaa
tacagagaatggcatcatttcctggtggtcaacatgaagggcaatgacatcagcagtggc
acagtcctctccgattatgtgggctcggggcctcccaagggcacaggcctccaccgctat
gtctggctggtttacgagcaggacaggccgctaaagtgtgacgagcccatcctcagcaac
cgatctggagaccaccgtggcaaattcaaggtggcgtccttccgtaaaaagtatgagctc
agggccccggtggctggcacgtgttaccaggccgagtgggatgactatgtgcccaaactg
tacgagcagctgtctgggaagtag

Protein Sequence

>5037 : length: 187
MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKVLTPTQVKNRPTSISWDGLDS
GKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRY
VWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKL
YEQLSGK



')