| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 50507 |
Name | NOX4 |
Synonym | KOX|KOX-1|RENOX;NADPH oxidase 4;NOX4;NADPH oxidase 4 |
Definition | kidney oxidase-1|kidney superoxide-producing NADPH oxidase|renal NAD(P)H-oxidase |
Position | 11q14.2-q21 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "Increased expression of p22(phox) and Nox4 in PPHN lungs, PA, and PASMC was associated with increased reactive oxygen species in PPHN PA, increased protein thiol oxidation in PPHN PASMC, and a decreased activity of extracellular superoxide dismutase (ecSOD) in the lungs and PASMC". |
| More detail of all Human literatures about NOX4 | |
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Pathways and Diseases |
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Pathway | Signaling events mediated by PTP1B;PID Curated;200033 |
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External Links |
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Links to Entrez Gene | 50507 |
Links to all GeneRIF Items | 50507 |
Links to iHOP | 50507 |
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Sequence Information |
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Nucleotide Sequence |
>50507 : length: 1617 atggctgtgtcctggaggagctggctcgccaacgaaggggttaaacacctctgcctgttc atctggctctccatgaatgtcctgcttttctggaaaaccttcttgctgtataaccaaggg ccagagtatcactacctccaccagatgttggggctaggattgtgtctaagcagagcctca gcatctgttcttaacctcaactgcagccttatccttttacccatgtgccgaacactcttg gcttacctccgaggatcacagaaggttccaagcaggagaaccaggagattgttggataaa agcagaacattccatattacctgtggtgttactatctgtattttctcaggcgtgcatgtg gctgcccatctggtgaatgccctcaacttctcagtgaattacagtgaagactttgttgaa ctgaatgcagcaagataccgagatgaggatcctagaaaacttctcttcacaactgttcct ggcctgacaggggtctgcatggtggtggtgctattcctcatgatcacagcctctacatat gcaataagagtttctaactatgatatcttctggtatactcataacctcttctttgtcttc tacatgctgctgacgttgcatgtttcaggagggctgctgaagtatcaaactaatttagat acccaccctcccggctgcatcagtcttaaccgaaccagctctcagaatatttccttacca gagtatttctcagaacattttcatgaacctttccctgaaggattttcaaaaccggcagag tttacccagcacaaatttgtgaagatttgtatggaagagcccagattccaagctaatttt ccacagacttggctttggatttctggacctttgtgcctgtactgtgccgaaagactttac aggtatatccggagcaataagccagtcaccatcatttcggtcataagtcatccctcagat gtcatggaaatccgaatggtcaaagaaaattttaaagcaagacctggtcagtatattact ctacattgtcccagtgtatctgcattagaaaatcatccatttaccctcacaatgtgtcca actgaaaccaaagcaacatttggggttcatcttaaaatagtaggagactggacagaacga tttcgagatttactactgcctccatctagtcaagactccgaaattctgcccttcattcaa tctagaaattatcccaaggatgactggaaaccatacaagcttagaagactatactttatt tgggtatgcagagatatccagtccttccgttggtttgcagatttactctgtatgttgcat aacaagttttggcaagagaacagacctgactatgtcaacatccagctgtacctcagtcaa acagatgggatacagaagataattggagaaaaatatcatgcactgaattcaagactgttt ataggacgtcctcggtggaaacttttgtttgatgaaatagcaaaatataacagaggaaaa acagttggtgttttctgttgtggacccaattcactatccaagactcttcataaactgagt aaccagaacaactcatatgggacaagatttgaatacaataaagagtctttcagctga |
Protein Sequence |
>50507 : length: 538 MAVSWRSWLANEGVKHLCLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRAS ASVLNLNCSLILLPMCRTLLAYLRGSQKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHV AAHLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGLTGVCMVVVLFLMITASTY AIRVSNYDIFWYTHNLFFVFYMLLTLHVSGGLLKYQTNLDTHPPGCISLNRTSSQNISLP EYFSEHFHEPFPEGFSKPAEFTQHKFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLY RYIRSNKPVTIISVISHPSDVMEIRMVKENFKARPGQYITLHCPSVSALENHPFTLTMCP TETKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPKDDWKPYKLRRLYFI WVCRDIQSFRWFADLLCMLHNKFWQENRPDYVNIQLYLSQTDGIQKIIGEKYHALNSRLF IGRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQNNSYGTRFEYNKESFS |