| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 5137 |
Name | PDE1C |
Synonym | Hcam3;phosphodiesterase 1C, calmodulin-dependent 70kDa;PDE1C;phosphodiesterase 1C, calmodulin-dependent 70kDa |
Definition | Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A)|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C|cam-PDE 1C|hCam-3 |
Position | 7p14.3 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | Strong upregulation of PDE1C in pulmonary arterial vessels in the idiopathic PAH lungs compared with healthy donor lungs was noted on the mRNA level by laser-assisted vessel microdissection and on the protein level by immunohistochemistry. |
| More detail of all Human literatures about PDE1C | |
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Pathways and Diseases |
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Pathway | Purine metabolism;KEGG PATHWAY;hsa00230 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Opioid Signalling;Reactome;REACT:15295 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | Olfactory transduction;KEGG PATHWAY;hsa04740 |
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External Links |
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Links to Entrez Gene | 5137 |
Links to all GeneRIF Items | 5137 |
Links to iHOP | 5137 |
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Sequence Information |
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Nucleotide Sequence |
>5137 : length: 1905 atggagtcgccaaccaaggagattgaagaatttgagagcaactctctgaaatacctgcaa ccggaacagatcgagaaaatctggcttcggctccgcgggctgaggaaatataagaaaacg tcccagagattacggtctttggtcaaacaattagagagaggggaagcttcagtggtagat cttaagaagaatttggaatatgcagccacagtgcttgaatctgtgtatattgatgaaaca aggagactcctggatacagaggatgagctcagtgacattcagtcagatgctgtgccttct gaggtccgagactggctggcctccaccttcacgcggcagatggggatgatgctcaggagg agcgacgagaagccccggttcaagagcatcgttcacgcagtgcaggctgggatatttgtg gagagaatgtatagacggacatcaaacatggttggactgagctatccaccagctgttatt gaggcattaaaggatgtggacaagtggtcctttgacgtcttttccctcaatgaggccagt ggggatcatgcactgaaatttattttctatgaactactcacacgttatgatctgatcagc cgtttcaagatccccatttctgcacttgtctcatttgtggaggccctggaagtgggatac agcaagcacaaaaatccttaccataacttaatgcacgctgccgatgttacacagacagtg cattacctcctctataagacaggagtggcgaactggctgacggagctggagatctttgct ataatcttctcagctgccatccatgactacgagcataccggaaccaccaacaatttccac attcagactcggtctgatccagctattctgtataatgacagatctgtactggagaatcac catttaagtgcagcttatcgccttctgcaagatgacgaggaaatgaatattttgattaac ctctcaaaggatgactggagggagtttcgaaccttggtaattgaaatggtgatggccaca gatatgtcttgtcacttccaacaaatcaaagcaatgaagactgctctgcagcagccagaa gccattgaaaagccaaaagccttatcccttatgctgcatacagcagatattagccatcca gcaaaagcatgggacctccatcatcgctggacaatgtcactcctggaggagttcttcaga cagggtgacagagaagcagagctggggctgcctttttctcctctgtgtgaccgaaagtcc actatggttgctcagtcacaagtaggtttcattgatttcatcgtggaacccaccttcact gtgcttacggacatgaccgagaagattgtgagtccattaatcgatgaaacctctcaaact ggtgggacaggacagaggcgttcgagtttgaatagcatcagctcgtcagatgccaagcga tcaggtgtcaagacctctggttcagagggaagtgccccgatcaacaattctgtcatctcc gttgactataagagctttaaagctacttggacggaagtggtgcacatcaatcgggagaga tggagggccaaggtacccaaagaggagaaggccaagaaggaagcagaggaaaaggctcgc ctggccgcagaggagcagcaaaaggaaatggaagccaaaagccaggctgaagaaggcgca tctggcaaagctgagaaaaagacgtctggagaaactaagaatcaagtcaatggaacacgg gcaaacaaaagtgacaaccctcgtgggaaaaactccaaagccgagaagtcatcaggagaa cagcaacagaatggtgacttcaaagatggtaaaaataagacagacaagaaggatcactct aacatcggaaatgattcaaagaaaacagatgattcacaagagtaa |
Protein Sequence |
>5137 : length: 634 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDDSQE |