| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 55107 |
Name | ANO1 |
Synonym | DOG1|ORAOV2|TAOS2|TMEM16A;anoctamin 1, calcium activated chloride channel;ANO1;anoctamin 1, calcium activated chloride channel |
Definition | anoctamin-1|discovered on gastrointestinal stromal tumors protein 1|oral cancer overexpressed 2|transmembrane protein 16A (eight membrane-spanning domains)|tumor-amplified and overexpressed sequence 2 |
Position | 11q13.3 |
Gene Type | protein-coding |
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PAH Type |
Description |
PH | augmented Cl(Ca)/TMEM16A channel activity is a major contributor to the changes in electromechanical coupling of pulmonary artery in this model of pulmonary hypertension. |
| More detail of all Human literatures about ANO1 | |
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External Links |
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Links to Entrez Gene | 55107 |
Links to all GeneRIF Items | 55107 |
Links to iHOP | 55107 |
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Sequence Information |
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Nucleotide Sequence |
>55107 : length: 2961 atgagggtcaacgagaagtactcgacgctcccggccgaggaccgcagcgtccacatcatc aacatctgcgccatcgaggacatcggctacctgccgtccgagggcacgctgctgaactcc ttatctgtggaccctgatgccgagtgcaagtatggcctgtacttcagggacggccggcgc aaggtggactacatcctggtgtaccatcacaagaggccctcgggcaaccggaccctggtc aggagggtgcagcacagcgacaccccctctggggctcgcagcgtcaagcaggaccacccc ctgccgggcaagggggcgtcgctggatgcaggctcgggggagcccccgatggactaccac gaggatgacaagcgcttccgcagggaggagtacgagggcaacctcctggaggcgggcctg gagctggagcgggacgaggacactaaaatccacggagtcgggtttgtgaaaatccatgcc ccctggaacgtgctgtgcagagaggccgagtttctgaaactgaagatgccgacgaagaag atgtaccacattaatgagacccgtggcctcctgaaaaaaatcaactctgtgctccagaaa atcacagatcccatccagcccaaagtggctgagcacaggccccagaccatgaagagactc tcctatcccttctcccgggagaagcagcatctatttgacttgtctgataaggattccttt ttcgacagcaaaacccggagcacgattgtctatgagatcttgaagagaacgacgtgtaca aaggccaagtacagcatgggcatcacgagcctgctggccaatggtgtgtacgcggctgca tacccactgcacgatggagactacaacggtgaaaacgtcgagttcaacgacagaaaactc ctgtacgaagagtgggcacgctatggagttttctataagtaccagcccatcgacctggtc aggaagtattttggggagaagatcggcctgtacttcgcctggctgggcgtgtacacccag atgctcatccctgcctccatcgtgggaatcattgtcttcctgtacggatgcgccaccatg gatgaaaacatccccagcatggagatgtgtgaccagagacacaatatcaccatgtgcccg ctttgcgacaagacctgcagctactggaagatgagctcagcctgcgccacggcccgcgcc agccacctcttcgacaaccccgccacggtcttcttctctgtcttcatggccctctgggct gccaccttcatggagcactggaagcggaaacagatgcgactcaactaccgctgggacctc acgggctttgaagaggaagaggaggctgtcaaggatcatcctagagctgaatacgaagcc agagtcttggagaagtctctgaagaaagagtccagaaacaaagagaagcgccggcatatt ccagaggagtcaacaaacaaatggaagcagagggttaagacagccatggcgggggtgaaa ttgactgacaaagtgaagctgacatggagagatcggttcccagcctacctcactaacttg gtctccatcatcttcatgattgcagtgacgtttgccatcgtcctcggcgtcatcatctac agaatctccatggccgccgccttggccatgaactcctccccctccgtgcggtccaacatc cgggtcacagtcacagccaccgcagtcatcatcaacctagtggtcatcatcctcctggac gaggtgtatggctgcatagcccgatggctcaccaagatcgaggtcccaaagacggagaaa agctttgaggagaggctgatcttcaaggctttcctgctgaagtttgtgaattcctacacc cccatcttttacgtggcgttcttcaaaggccggtttgttggacgcccgggcgactacgtg tacattttccgttccttccgaatggaagagtgtgcgccagggggctgcctgatggagcta tgcatccagctcagcatcatcatgctggggaaacagctgatccagaacaacctgttcgag atcggcatcccgaagatgaagaagctcatccgctacctgaagctgaagcagcagagcccc cctgaccacgaggagtgtgtgaagaggaaacagcggtacgaggtggattacaacctggag cccttcgcgggcctcaccccagagtacatggaaatgatcatccagtttggcttcgtcacc ctgtttgtcgcctccttccccctggccccactgtttgcgctgctgaacaacatcatcgag atccgcctggacgccaaaaagtttgtcactgagctccgaaggccggtagctgtcagagcc aaagacatcggaatctggtacaatatcctcagaggcattgggaagcttgctgtcatcatc aatgccttcgtgatctccttcacgtctgacttcatcccgcgcctggtgtacctctacatg tacagtaagaacgggaccatgcacggcttcgtcaaccacaccctctcctccttcaacgtc agtgacttccagaacggcacggcccccaatgaccccctggacctgggctacgaggtgcag atctgcaggtataaagactaccgagagccgccgtggtcggaaaacaagtacgacatctcc aaggacttctgggccgtcctggcagcccggctggcgtttgtcatcgtcttccagaacctg gtcatgttcatgagcgactttgtggactgggtcatcccggacatccccaaggacatcagc cagcagatccacaaggagaaggtgctcatggtggagctgttcatgcgggaggagcaagac aagcagcagctgctggaaacctggatggagaaggagcggcagaaggacgagccgccgtgc aaccaccacaacaccaaagcctgcccagacagcctcggcagcccagcccccagccatgcc taccacgggggcgtcctgtag |
Protein Sequence |
>55107 : length: 986 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF FDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKL LYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWA ATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHI PEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEK SFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRA KDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNV SDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNL VMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPC NHHNTKACPDSLGSPAPSHAYHGGVL |