Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6262

Name

RYR2

Synonym

ARVC2|ARVD2|RYR-2|RyR|VTSIP;ryanodine receptor 2 (cardiac);RYR2;ryanodine receptor 2 (cardiac)

Definition

cardiac muscle ryanodine receptor-calcium release channel|cardiac-type ryanodine receptor|islet-type ryanodine receptor|kidney-type ryanodine receptor|ryanodine receptor 2|type 2 ryanodine receptor

Position

1q43

Gene Type

protein-coding

PAH Type

Description

HPH

Relevance of the TRPV4-RyR2 signaling pathway under hypoxic conditions that may lead to pulmonary hypertension.
More detail of all Rat literatures about RYR2

Pathways and Diseases

Pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC);KEGG PATHWAY;hsa05412

Pathway

Pancreatic secretion;KEGG PATHWAY;hsa04972

Pathway

Beta2 adrenergic receptor signaling pathway;PANTHER;P04378

Pathway

Beta1 adrenergic receptor signaling pathway;PANTHER;P04377

Pathway

Dilated cardiomyopathy;KEGG PATHWAY;hsa05414

Pathway

Hypertrophic cardiomyopathy (HCM);KEGG PATHWAY;hsa05410

Pathway

Calcium signaling pathway;KEGG PATHWAY;hsa04020

Pathway

Cardiac muscle contraction;KEGG PATHWAY;hsa04260

Pathway

actions of nitric oxide in the heart;PID BioCarta;100094

Disease

CANCER;GAD

Disease

Acute lymphoblastic leukemia (childhood);NHGRI

Disease

Heart failure;FunDO

Disease

Arrhythmogenic right ventricular cardiomyopathy (ARVC);KEGG DISEASE;H00293

Disease

Circulatory system diseases;KEGG DISEASE

Disease

Sudden infant death syndrome;FunDO

Disease

Exercise treadmill test traits;NHGRI

Disease

exercise treadmill test traits;GAD

Disease

CARDIOVASCULAR;GAD

Disease

Ventricular tachycardia, catecholaminergic polymorphic, 1;OMIM

Disease

Hypertension;NHGRI

Disease

Melanoma;FunDO

Disease

Cardiac diseases;KEGG DISEASE

Disease

hypertension;GAD

Disease

Arrhythmogenic right ventricular dysplasia 2;OMIM

Disease

Long QT syndrome;FunDO

Disease

Acute lymphoblastic leukemia (childhood);GAD

External Links

Links to Entrez Gene

6262

Links to all GeneRIF Items

6262

Links to iHOP

6262

Sequence Information

Nucleotide Sequence

>6262 : length: 14904
atggccgatgggggcgagggcgaagacgagatccagttcctgcgaactgatgatgaagtg
gttctgcagtgcaccgcaaccatccacaaagaacaacagaagctatgcttggcagcagaa
ggatttggcaacagactttgtttcttggagtccacttccaattccaagaatgtgccccca
gacctctccatctgcacctttgtgctggagcagtccctctctgtccgggcgctgcaggag
atgctggctaacaccgtggagaaatcagaagggcaagttgatgtggaaaaatggaaattc
atgatgaagactgctcaaggtggtggtcatcgaacactcctctacggacatgccatattg
ctgcgccattcctatagtggcatgtatctgtgctgcctgtccacctcccggtcttcaact
gataagctggcttttgatgttggcttgcaagaggacaccacaggggaggcttgttggtgg
accatacaccctgcctctaagcagcgatcagaaggagaaaaagtacgagttggagatgac
ctcatcttagttagcgtgtcctctgaaaggtacttgcacttgtcttatggcaacggcagc
ttacacgtggatgccgctttccagcagactctctggagcgtggccccaatcagctcagga
agtgaggcagcccaagggtatctcattggtggtgatgtcctcaggttgctgcatggacac
atggacgagtgtctcactgtcccttcaggagaacatggtgaagagcagcggagaactgtt
cattatgaaggtggcgctgtgtctgttcatgcacgttccctttggagactagagacgcta
agagttgcgtggagtggaagccacataagatggggacagccattccgactacgccatgtc
acaacaggaaaatacttgagtctcatggaagacaaaaaccttctactcatggacaaagag
aaagctgatgtaaaatcaacagcatttaccttccggtcttccaaggaaaaattggatgta
ggggtgagaaaagaagtagatggcatgggaacatctgaaataaaatacggtgactcagta
tgctatatacaacatgtagacacaggcctatggcttacttaccagtctgtggacgtgaaa
tccgtgagaatgggatctatacaacgtaaggctattatgcatcatgaaggccacatggat
gatggcataagtttgtcgagatcccagcatgaagaatcacgcacagcccgagttatccgg
agcacagtcttccttttcaatagatttataaggggccttgatgctctcagcaagaaagcg
aaggcttccacagtcgatttgcctatagagtccgtaagcctaagtctgcaggatctcatt
ggctacttccaccccccagatgagcatttagagcatgaagacaaacagaacagactacga
gccctgaagaatcggcaaaatctcttccaggaagagggaatgatcaacctcgtgcttgag
tgcatagaccgtttgcacgtctacagcagtgcagcacactttgctgatgttgctgggcga
gaagcaggagagtcttggaaatccattctgaattctctgtatgagttgctggcggctcta
attagaggaaatcgtaaaaactgtgctcaattttctggctccctcgactggttgatcagc
agattggaaagactggaagcttcttcaggcattctggaagttttacactgtgttttagta
gaaagtccagaagctctaaatattattaaagaaggacatattaaatctattatctcactt
ttagacaaacatggaagaaatcacaaggttctggatgtcttgtgctcactctgtgtttgc
cacggggttgcagtccgttctaaccagcatctcatctgtgacaatctcctaccaggaaga
gacttgttattgcagacacgtcttgtgaaccatgtcagcagcatgagacccaatattttt
ctgggcgtcagtgaaggttctgctcagtataagaaatggtactatgaattgatggtggac
cacacagagccctttgtgacagctgaagcaactcacctgcgagtgggctgggcttccact
gaaggatattctccctaccctggagggggcgaagagtggggtggaaatggtgttggagat
gatctcttctcctatggatttgatggccttcatctctggtcaggttgtattgctcgtact
gtaagctcaccaaaccaacatctgttaagaactgatgatgtcatcagttgctgtttagat
ctgagtgccccaagcatctcgttccgaattaatggacaacctgttcaaggaatgtttgag
aatttcaacatcgatggcctcttctttccagtcgttagtttctctgcaggaataaaagta
cgctttctgcttggagggcgacatggagaattcaaatttcttcctccacctgggtatgct
ccttgttatgaagctgttctgccaaaagaaaagttgaaagtggaacacagccgagagtac
aagcaagaaagaacttacacacgcgacctgctgggccccacagtttccctgacgcaagct
gccttcacacccatccctgtggataccagccagatcgtgttgcctcctcatctagaaaga
ataagagaaaaactggcagagaatatccatgaactctgggttatgaataaaattgagctt
ggctggcagtatggtccggttagagatgacaacaagagacaacacccatgcctggtggag
ttctccaagctgcctgaacaggagcgcaattacaacttacaaatgtcgcttgagaccctg
aagactttgttggcattaggatgtcatgtgggtatatcagatgaacatgctgaagacaag
gtgaaaaaaatgaagctacccaagaattaccagctgacaagtggatacaagcctgcccct
atggacctgagctttatcaaactcaccccatcacaagaagcaatggtggacaagttggca
gaaaatgcacataatgtgtgggcgcgggatcgaatccggcagggctggacttatggcatc
caacaggacgtaaagaacagaagaaatcctcgccttgttccctacactcttctggatgac
cgaaccaagaaatccaacaaggacagcctccgcgaggctgtgcgcacgctgctggggtac
ggctacaacttggaagcaccagatcaagatcatgcagccagagccgaagtgtgcagcggc
accggggaaaggttccgaatcttccgtgccgagaagacctatgcagtgaaggccggacgg
tggtattttgaatttgagacggtcactgctggagacatgagggttggttggagtcgtcct
ggttgtcaaccggatcaggagcttggctcagatgaacgtgcctttgcctttgatggcttc
aaggcccagcggtggcatcagggcaatgaacactatgggcgctcttggcaagcaggcgat
gtcgtggggtgtatggttgacatgaacgaacacaccatgatgttcacactgaatggtgaa
atccttcttgatgattcaggctcagaactggctttcaaggactttgatgttggcgatgga
ttcatacctgtgtgtagccttggagtggctcaagtgggtaggatgaactttggaaaggat
gtcagcaccttgaaatatttcaccatctgtggcttacaagagggctatgaaccatttgcc
gttaatacaaacagggatattaccatgtggctgagcaagaggcttcctcagtttcttcaa
gttccatcaaaccatgaacatatagaggtgaccagaatagacggcaccatagacagttcc
ccatgtttaaaggtcactcagaagtcttttggttctcagaacagcaacactgatatcatg
ttttatcgcctgagcatgccgatcgagtgcgcggaggtcttctccaagacggtggctgga
gggctccctggggctggcctttttgggcccaagaatgacttggaagattatgatgctgat
tctgactttgaggttctgatgaagacagctcatggccatctagtgcccgatcgtgttgac
aaagacaaagaagctactaaaccagagtttaacaaccacaaagattatgcccaggaaaag
ccctctcgtctgaaacaaagatttttgcttagaagaacaaagccagattacagcacaagc
cattctgcaagactcaccgaagatgtccttgctgatgatcgggatgactatgatttcttg
atgcaaacgtccacgtactattactcagtgagaatctttcctggacaagaacctgctaat
gtctgggtgggctggattacatcagatttccatcagtatgacacaggctttgacttggac
agagttcgcacagtaacagttactctaggagatgaaaaaggaaaagtgcatgaaagcatc
aaacgcagcaactgctatatggtatgtgcgggtgagagcatgagccccgggcaaggacgc
aacaataatggactggagattggctgtgtggtggatgctgccagcgggctgctcacattc
attgccaatggcaaggaactgagcacatactatcaggtggaaccgagtacaaaattattt
cctgcggtttttgcacaagctacaagtcccaatgttttccagtttgagttgggaagaata
aagaatgtgatgcctctctcggcgggattattcaagagtgagcacaagaaccccgtgccg
cagtgccccccgcgcctccacgtgcagttcctgtcacacgtcctgtggagcagaatgccc
aaccagtttttgaaggtagatgtgtctcgaataagtgaacgccaaggctggttggtgcag
tgtttggatcctctgcagttcatgtctcttcatatccctgaggaaaacagatctgttgac
atcttagagttgacagagcaggaggaattgctgaaatttcactatcacactctccggctc
tactcagccgtctgtgctcttgggaaccaccgggtggcccatgccctgtgcagccatgtg
gatgaacctcagctcctctatgccattgagaacaagtacatgcctggtttgctgcgtgct
ggctactatgacctgctgattgacatccacctgagctcctatgccactgccaggctcatg
atgaacaacgagtacattgtccccatgacggaggagacgaagagcatcaccctgttccct
gatgagaacaaaaaacacggccttccagggatcggcctcagcacctccctcaggccacgg
atgcagttttcctcccccagttttgtaagcattagtaatgaatgttaccagtacagtcca
gagttcccactggacatcctcaagtccaaaaccatacagatgctgacagaagctgttaaa
gagggcagtcttcatgcccgggacccagttggagggactactgaattcctctttgtacct
ctcatcaagcttttctataccctgctgatcatgggcatctttcacaacgaggacttgaag
cacatcttgcagttgattgagcccagtgtgtttaaagaagctgccactccggaggaggag
agtgacacgctggagaaagagctcagtgtggacgatgcaaagctgcaaggagctggtgag
gaagaagccaaggggggcaagcggcccaaggaaggcctgctccaaatgaaactgccagag
ccagttaaattgcagatgtgcctactgcttcagtacctctgtgactgccaggtccggcac
cggatagaagccattgtagccttttcagatgattttgtggctaagctccaagacaatcaa
cgtttccgatacaacgaagtcatgcaagccttaaacatgtcagctgcactcacagccagg
aagacaaaggaatttagatcaccacctcaagaacagatcaatatgcttctcaattttaag
gatgacaaaagtgaatgtccatgtccagaagaaattcgtgaccaactattggatttccat
gaagatttgatgacacattgtggaattgagctggatgaagatgggtctctggatggaaac
agtgatttaacaattagagggcgtctgctatccctggtagaaaaggtgacatatctgaag
aagaagcaagcagaaaaaccagttgagagtgactccaaaaagtcctccactctgcagcag
ctgatttctgagaccatggtccgatgggctcaggagtctgtcattgaagaccccgagctg
gtgagggccatgtttgtgttgctccatcggcagtatgacggcattgggggtcttgttcgg
gccctgccaaagacctacacgataaatggtgtgtccgtggaggacaccatcaacctgctg
gcatcccttggtcagattcggtccctgctgagtgtgagaatgggcaaagaagaagagaag
ctcatgattcgtggattaggggatattatgaataacaaagtgttttaccagcaccctaat
ctcatgagggcactggggatgcacgagactgtgatggaggtcatggtgaacgtccttgga
ggtggagagtccaaggaaatcacctttcccaagatggtggccaactgttgccgttttctc
tgttacttctgtcgtataagtaggcagaatcaaaaagctatgtttgatcatctcagttat
ttactggaaaacagcagtgttggtcttgcctccccagctatgagaggttcaacaccactg
gatgtggctgcagcttcggtgatggataataatgaactagcattagctctgcgtgagccg
gatctagaaaaggtagttcgttatttggctggttgtggactgcaaagttgccagatgctg
gtgtctaagggctatccagacattgggtggaacccagttgaaggagagagatatcttgac
tttcttagatttgctgtcttctgtaatggggagagtgtggaggaaaatgcaaatgtcgtg
gtgagattgctcattcggaggcctgagtgttttggtcctgctttgagaggagaaggtggg
aatgggcttcttgcagcaatggaagaagccatcaaaatcgccgaggatccttcccgagat
ggtccctcaccaaatagcggatccagtaaaacacttgacacagaggaggaggaagatgac
actatccacatggggaacgcgatcatgaccttctattcagctttgattgacctcttggga
cgctgtgctcctgagatgcatttgattcatgccgggaagggagaagccatcagaattagg
tccattttgagatccctcattcccctgggagatttggtgggcgttatcagcatcgctttt
cagatgccaacaatagccaaagatgggaatgtggtggaacctgacatgtctgcggggttt
tgcccagatcacaaggcagccatggttttattccttgacagggtctatgggattgaggtt
caagacttcctcctccatcttcttgaggttggctttctgccagatctccgggcggctgct
tctttagatacggcagctttgagtgctacagacatggccttggccctcaatcggtacctt
tgcacagccgtcttgccattgttaacaagatgtgctcctctctttgctggcacagagcac
cacgcttctctcattgactcattacttcatactgtgtatagactttctaagggctgttca
cttaccaaagctcagcgggattccatagaagtttgtttactctctatttgtggacaactg
agaccttctatgatgcagcacttactcagaagattagtatttgatgttccattattaaat
gaacacgcaaagatgcctcttaaactgctgacaaatcattatgaaagatgctggaaatat
tactgcctgcctggagggtggggaaactttggtgctgcctcagaagaagaacttcattta
tcaagaaagttgttctggggcatttttgatgccctgtctcaaaagaaatatgaacaagaa
cttttcaaactggcactgccttgcctgagtgcagttgcgggagctttgcctccagactac
atggagtcaaattatgtcagtatgatggaaaaacagtcatcaatggattctgaagggaac
tttaacccacaacctgttgatacctcaaatattacaattcctgagaaattggaatacttc
attaacaaatatgcagaacactcccatgacaaatggtcaatggacaagttggcaaatgga
tggatttatggagaaatatattcagactcttctaaggttcagccattaatgaagccatat
aagctattgtctgaaaaggaaaaagaaatttatcgctggccaatcaaagaatctttaaaa
actatgctggcttggggctggagaattgaaagaactcgggagggagacagcatggccctt
tacaaccggactcgtcgtatttctcagacaagccaggtttctgtggacgctgcccatggt
tacagtccccgggccattgacatgagcaatgttacactatctagagacctgcatgctatg
gcagaaatgatggctgaaaactaccataatatatgggcaaagaaaaagaaaatggagttg
gagtccaaaggaggaggaaaccatcctctgctggtgccctatgatacactgacagccaaa
gagaaagccaaggatagagaaaaagcacaggacatcctcaagttcttgcagatcaatgga
tatgctgtatccagaggatttaaggacctggaactggacacgccttctattgagaaacga
tttgcctatagtttcctccaacaactcattcgctatgtggatgaagcccatcagtatatc
ctggagtttgatggtggcagcagaggcaaaggagaacatttcccttatgaacaagaaatc
aagttctttgcaaaagtcgttcttcctttaattgatcagtatttcaaaaaccatcgttta
tacttcttatctgcagcaagcagacctctctgctctggaggacatgcttccaacaaagag
aaagaaatggtgactagcctattctgcaaacttggagttcttgtcaggcataggatttca
ctatttggcaatgatgcaacatcaattgtcaactgtcttcatattttgggtcagactttg
gatgcaaggacagtgatgaagactggcctggagagtgttaaaagtgcactcagagctttt
ctggacaacgctgcagaggatctggagaagaccatggaaaacctcaagcagggccagttc
actcacacccgaaaccagcccaaaggggttactcagattatcaattacaccacagtggcc
ctgctgccaatgctgtcttcattatttgaacatattggccagcatcagttcggagaagac
ctaatattggaagatgtccaggtgtcttgttatagaattctgactagcttatatgctttg
ggaaccagcaagagtatttacgtggagaggcaacgttctgcattaggagaatgtctagct
gcctttgctggtgcttttcctgtagcatttttggaaactcatctggacaaacataatatt
tactccatctacaataccaagtcttcacgagaaagagcagctctcagtttgccaactaat
gtggaagatgtttgtccaaacataccgtctttggagaaactcatggaagaaatcgtggaa
ttagccgagtccggcattcgctacactcaaatgccacatgtcatggaagtcatactgccc
atgctttgcagctacatgtctcgttggtgggagcatggacctgagaacaatccagaacgg
gccgagatgtgctgcacagccctgaactcagagcacatgaacacacttctagggaacata
ttgaaaatcatatataataacttggggattgatgagggagcctggatgaagaggctagca
gtgttttcccagcctataataaataaagtgaaacctcagctcttgaaaactcatttcttg
ccgttaatggagaaactcaagaaaaaggcagctacggtggtgtctgaggaagaccacctg
aaagctgaggccaggggggacatgtcggaggcagaactcctcatcctagatgagttcacc
acactggccagagatctctatgccttctaccctctcttgattagatttgtggactataac
agggcaaagtggctaaaggagcctaacccagaagcagaggagctcttccgcatggtggct
gaagtgtttatctactggtcgaagtcccataatttcaaaagagaagagcagaacttcgtt
gtacagaatgaaatcaacaatatgtctttccttattactgataccaagtcaaagatgtca
aaggcagctgtttctgatcaggaaaggaagaaaatgaagcgcaaaggagatcggtattcc
atgcagacctctctgattgtagcagctctgaagcggttactgcccattgggttgaacatc
tgtgcccctggggaccaggagctcattgctctggccaaaaatcgatttagcctgaaagat
accgaggatgaagtacgagatataatccgcagcaatattcatttacaaggcaagttggag
gatcctgctattagatggcaaatggctctttacaaagacttaccaaacaggactgatgat
acctcagatccagagaagacggtagaaagagtattggatatagcaaatgtgctttttcat
cttgaacagaagtctaaacgtgtgggtcggagacattactgtctggtggaacatcctcag
agatctaaaaaggctgtatggcataaactactgtccaagcagaggaaaagggctgttgta
gcctgcttccggatggcccccttatataatctgccaaggcatcgggctgtcaatctcttt
cttcagggatatgaaaagtcttggattgaaacagaagaacattactttgaagataaactg
atagaagatttagcaaaacctggggctgaacctccagaagaagatgaaggcactaagaga
gttgatcctctacatcagctgatccttctgtttagtcggacagctttaacagagaaatgc
aaactggaggaagattttttatatatggcctatgcagatattatggcaaagagttgtcat
gatgaggaagatgacgatggtgaagaggaagtgaagagttttgaagaaaaagaaatggaa
aagcaaaagcttctataccagcaagcccgactccacgatcgtggcgcggctgagatggtg
ctacagacaatcagtgccagcaaaggtgaaactggaccaatggtagcagctactctgaaa
cttggaattgctattttaaatggtgggaactccacagtacagcagaaaatgcttgactac
ctcaaggagaaaaaggatgtgggcttctttcagagcctggccggcctgatgcagtcatgt
agtgtccttgacctaaatgcatttgagcgacaaaacaaagctgaaggtcttgggatggtg
acagaggaaggatcaggagaaaaggttctgcaggacgatgagttcacctgtgacctcttc
cgattcctgcaactactctgtgagggacacaactcagattttcagaattatctgagaact
cagactggcaataatacaactgtcaacataattatctccactgtagactacctactgaga
gttcaggaatcaattagtgacttttattggtattactctgggaaagatgttattgatgaa
caaggacaacggaatttctccaaagctatccaagtggcaaaacaagtctttaacactctt
acagagtatattcagggtccttgcactgggaatcaacagagtttggcacacagcaggctg
tgggatgctgtggtcggctttcttcatgtgtttgcccatatgcagatgaagctgtcgcag
gattccagtcaaattgagctattaaaagaattaatggatctgcagaaggatatggtggtc
atgttgctgtccatgttagaaggtaatgttgttaatggaacgattggcaaacagatggtg
gatatgcttgtggaatcttccaacaacgtggagatgattctcaaattttttgacatgttc
ttaaaactaaaggatttgacgtcgtctgatacttttaaagaatatgaccccgatggcaag
ggagtcatttccaagagggacttccacaaagcgatggagagccataagcactacacgcag
tcagaaacggaatttcttttgtcttgtgcggagacggatgagaatgaaaccctcgactac
gaagagttcgtcaaacgcttccacgaacctgcgaaggacatcggcttcaacgtcgccgtc
cttctgacaaacctctctgagcacatgcccaacgatacccgacttcagacttttctggaa
ttagcagagagcgtcctgaattatttccagccctttctgggccgcatcgaaatcatggga
agcgccaaacgcatcgagagggtctattttgaaatcagtgagtccagccgaacccagtgg
gagaagccccaggtcaaggagtccaaaagacagttcatatttgacgtggtcaacgaaggc
ggagagaaagagaagatggaactctttgtgaacttctgcgaggacaccatctttgaaatg
cagctggcggctcagatctcggagtcggacttgaacgagaggtcagcgaataaggaagaa
agcgagaaggagaggccggaagagcaggggccgaggatggctttcttctccattctgacg
gtcaggtcggccctgtttgcgctcaggtacaatatcttgacccttatgcgaatgctcagt
ctgaagagcctgaagaagcagatgaaaaaagtaaaaaagatgaccgtgaaggacatggtc
acggccttcttttcatcctactggagtattttcatgaccctcttgcacttcgtggccagc
gttttcagaggctttttccgcatcatttgcagcctgctgcttgggggaagcctcgtcgaa
ggtgctaaaaagatcaaagttgcagaactgttagccaacatgccagaccccactcaggat
gaggttagaggagatggggaggagggagagaggaaacccctggaagccgccctgccctcc
gaggatctgaccgacttaaaggagctgacagaggaaagtgaccttctttcggacatcttt
ggcctggatctgaagagagaaggaggacagtacaaactgattcctcataatccaaatgct
gggctcagtgacctcatgagcaacccagtccccatgcctgaggtgcaggaaaaatttcag
gaacagaaggcaaaagaagaagaaaaggaagaaaaagaagaaaccaaatctgaacctgaa
aaagccgagggagaagatggagaaaaagaagagaaagccaaggaagacaagggcaaacaa
aagttgaggcagcttcacacacacagatacggagaaccagaagtgccagagtcagcattc
tggaagaaaatcatagcatatcaacagaaacttctaaactattttgctcgcaacttttac
aacatgagaatgttagccttatttgtcgcatttgctatcaatttcatcttgctcttttat
aaggtctccacttcttctgtggttgaaggaaaggagctccccacgagaagttcaagtgaa
aatgccaaagtgacaagcctggacagcagctcccatagaatcatcgcagttcactatgta
ctagaggagagcagcggctacatggagcccacgttgcgtatcttagctattctgcacacg
gtcatttctttcttctgcatcattggatactactgcttgaaagtcccattggttattttt
aagcgagaaaaggaagtggcacggaaattggaatttgatgggctttatattacagaacag
ccttcagaagatgatattaaaggccagtgggatagactcgtaatcaacacacagtcattt
cccaacaactactgggacaaatttgttaaaagaaaggttatggataaatatggagagttc
tacggccgagacagaatcagtgaattacttggcatggacaaggcagctctggacttcagt
gatgccagagaaaagaagaagccaaagaaagacagctccttatcagctgtactgaactcc
attgatgtgaagtatcagatgtggaaactaggagtcgttttcactgacaactccttcctc
tacctagcctggtatatgactatgtctgttcttggacactataacaactttttttttgcc
gctcaccttctcgacattgctatgggattcaagacattaagaaccatcttgtcctcagta
actcacaatggcaaacagctcgtattaaccgttggcttattagctgttgttgtataccta
tacactgtggtggcattcaattttttccgaaaattctacaataaaagtgaagatggtgat
acaccagatatgaaatgtgacgatatgctaacatgctatatgttccacatgtatgttgga
gttcgtgctggaggagggatcggggatgaaatcgaagacccagcaggagatgaatatgag
atctatcgaatcatctttgacatcactttcttcttctttgttattgtcattctcttggcc
ataatacaaggtctaattattgatgcttttggagaactaagagaccaacaggaacaagtc
aaagaagacatggagaccaaatgcttcatctgtgggataggcaatgattacttcgacaca
gtgccacatggctttgaaacccacactttacaggagcacaacttggctaattacttgttt
tttctgatgtatcttataaacaaagatgaaacagaacacacaggacaggaatcttatgtc
tggaagatgtatcaagaaaggtgttgggaatttttcccagcaggggattgcttccggaaa
cagtatgaagaccagctaaattaa

Protein Sequence

>6262 : length: 4967
MADGGEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPP
DLSICTFVLEQSLSVRALQEMLANTVEKSEGQVDVEKWKFMMKTAQGGGHRTLLYGHAIL
LRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDD
LILVSVSSERYLHLSYGNGSLHVDAAFQQTLWSVAPISSGSEAAQGYLIGGDVLRLLHGH
MDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHV
TTGKYLSLMEDKNLLLMDKEKADVKSTAFTFRSSKEKLDVGVRKEVDGMGTSEIKYGDSV
CYIQHVDTGLWLTYQSVDVKSVRMGSIQRKAIMHHEGHMDDGISLSRSQHEESRTARVIR
STVFLFNRFIRGLDALSKKAKASTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLR
ALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADVAGREAGESWKSILNSLYELLAAL
IRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISL
LDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIF
LGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGD
DLFSYGFDGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFE
NFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREY
KQERTYTRDLLGPTVSLTQAAFTPIPVDTSQIVLPPHLERIREKLAENIHELWVMNKIEL
GWQYGPVRDDNKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGISDEHAEDK
VKKMKLPKNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGI
QQDVKNRRNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYNLEAPDQDHAARAEVCSG
TGERFRIFRAEKTYAVKAGRWYFEFETVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGF
KAQRWHQGNEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVGDG
FIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQ
VPSNHEHIEVTRIDGTIDSSPCLKVTQKSFGSQNSNTDIMFYRLSMPIECAEVFSKTVAG
GLPGAGLFGPKNDLEDYDADSDFEVLMKTAHGHLVPDRVDKDKEATKPEFNNHKDYAQEK
PSRLKQRFLLRRTKPDYSTSHSARLTEDVLADDRDDYDFLMQTSTYYYSVRIFPGQEPAN
VWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGESMSPGQGR
NNNGLEIGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRI
KNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLVQ
CLDPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNHRVAHALCSHV
DEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEYIVPMTEETKSITLFP
DENKKHGLPGIGLSTSLRPRMQFSSPSFVSISNECYQYSPEFPLDILKSKTIQMLTEAVK
EGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVFKEAATPEEE
SDTLEKELSVDDAKLQGAGEEEAKGGKRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRH
RIEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLNFK
DDKSECPCPEEIRDQLLDFHEDLMTHCGIELDEDGSLDGNSDLTIRGRLLSLVEKVTYLK
KKQAEKPVESDSKKSSTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVR
ALPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPN
LMRALGMHETVMEVMVNVLGGGESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSY
LLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCQML
VSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGG
NGLLAAMEEAIKIAEDPSRDGPSPNSGSSKTLDTEEEEDDTIHMGNAIMTFYSALIDLLG
RCAPEMHLIHAGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGNVVEPDMSAGF
CPDHKAAMVLFLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYL
CTAVLPLLTRCAPLFAGTEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQL
RPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWGNFGAASEEELHL
SRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSMMEKQSSMDSEGN
FNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPY
KLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYNRTRRISQTSQVSVDAAHG
YSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKMELESKGGGNHPLLVPYDTLTAK
EKAKDREKAQDILKFLQINGYAVSRGFKDLELDTPSIEKRFAYSFLQQLIRYVDEAHQYI
LEFDGGSRGKGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCSGGHASNKE
KEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLESVKSALRAF
LDNAAEDLEKTMENLKQGQFTHTRNQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGED
LILEDVQVSCYRILTSLYALGTSKSIYVERQRSALGECLAAFAGAFPVAFLETHLDKHNI
YSIYNTKSSRERAALSLPTNVEDVCPNIPSLEKLMEEIVELAESGIRYTQMPHVMEVILP
MLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLA
VFSQPIINKVKPQLLKTHFLPLMEKLKKKAATVVSEEDHLKAEARGDMSEAELLILDEFT
TLARDLYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIYWSKSHNFKREEQNFV
VQNEINNMSFLITDTKSKMSKAAVSDQERKKMKRKGDRYSMQTSLIVAALKRLLPIGLNI
CAPGDQELIALAKNRFSLKDTEDEVRDIIRSNIHLQGKLEDPAIRWQMALYKDLPNRTDD
TSDPEKTVERVLDIANVLFHLEQKSKRVGRRHYCLVEHPQRSKKAVWHKLLSKQRKRAVV
ACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPGAEPPEEDEGTKR
VDPLHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCHDEEDDDGEEEVKSFEEKEME
KQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLDY
LKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSGEKVLQDDEFTCDLF
RFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDE
QGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQ
DSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMF
LKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDY
EEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMG
SAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEM
QLAAQISESDLNERSANKEESEKERPEEQGPRMAFFSILTVRSALFALRYNILTLMRMLS
LKSLKKQMKKVKKMTVKDMVTAFFSSYWSIFMTLLHFVASVFRGFFRIICSLLLGGSLVE
GAKKIKVAELLANMPDPTQDEVRGDGEEGERKPLEAALPSEDLTDLKELTEESDLLSDIF
GLDLKREGGQYKLIPHNPNAGLSDLMSNPVPMPEVQEKFQEQKAKEEEKEEKEETKSEPE
KAEGEDGEKEEKAKEDKGKQKLRQLHTHRYGEPEVPESAFWKKIIAYQQKLLNYFARNFY
NMRMLALFVAFAINFILLFYKVSTSSVVEGKELPTRSSSENAKVTSLDSSSHRIIAVHYV
LEESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQ
PSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFS
DAREKKKPKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFA
AHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGD
TPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLA
IIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLF
FLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN



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