Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6275

Name

S100A4

Synonym

18A2|42A|CAPL|FSP1|MTS1|P9KA|PEL98;S100 calcium binding protein A4;S100A4;S100 calcium binding protein A4

Definition

S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)|fibroblast-specific protein-1|leukemia multidrug resistance associated protein|malignant transformation suppression 1|placental calcium-binding protein|pr

Position

1q21

Gene Type

protein-coding

PAH Type

Description

PAH

S100A4/Mts1 over-expression combined with female gender is permissive to the development of experimental pulmonary arterial hypertension in mice.

PAH

S100A4/Mts1 over-expression combined with female gender is permissive to the development of experimental pulmonary arterial hypertension in mice.

PAH

"Experimental studies attribute the manifestation of pulmonary vascular pathology in S100A4-overexpressing female mice to 17?-estradiol induction of receptor for advanced glycosylation end-products (RAGE), the S100A4 receptor."
More detail of all Mouse literatures about S100A4

External Links

Links to Entrez Gene

6275

Links to all GeneRIF Items

6275

Links to iHOP

6275

Sequence Information

Nucleotide Sequence

>6275 : length: 306
atggcgtgccctctggagaaggccctggatgtgatggtgtccaccttccacaagtactcg
ggcaaagagggtgacaagttcaagctcaacaagtcagaactaaaggagctgctgacccgg
gagctgcccagcttcttggggaaaaggacagatgaagctgctttccagaagctgatgagc
aacttggacagcaacagggacaacgaggtggacttccaagagtactgtgtcttcctgtcc
tgcatcgccatgatgtgtaacgaattctttgaaggcttcccagataagcagcccaggaag
aaatga

Protein Sequence

>6275 : length: 101
MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS
NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK



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