| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 6462 |
Name | SHBG |
Synonym | ABP|SBP|TEBG;sex hormone-binding globulin;SHBG;sex hormone-binding globulin |
Definition | sex steroid-binding protein|testis-specific androgen-binding protein|testosterone-binding beta-globulin|testosterone-estradiol-binding globulin|testosterone-estrogen-binding globulin |
Position | 17p13-p12 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PAH | Personal communication to Dr. Eric D. Austin. |
| More detail of all Human literatures about SHBG | |
|
Pathways and Diseases |
|
Pathway | Nongenotropic Androgen signaling;PID Curated;200145 |
Disease | Endocrine system disease;FunDO |
Disease | overall effect;GAD |
Disease | menarche;GAD |
Disease | Liver cancer;FunDO |
Disease | Breast cancer;FunDO |
Disease | IMMUNE;GAD |
Disease | prostate cancer;GAD |
Disease | protein quantitative trait loci;GAD |
Disease | hormone disturbance;GAD |
Disease | systemic lupus erythematosus;GAD |
Disease | Urogenital abnormalities;FunDO |
Disease | METABOLIC;GAD |
Disease | Fibroid tumor;FunDO |
Disease | Protein quantitative trait loci;NHGRI |
Disease | CANCER;GAD |
Disease | Female reproductive system disorder;FunDO |
Disease | REPRODUCTION;GAD |
Disease | Osteoporosis;FunDO |
Disease | breast cancer;GAD |
Disease | Testicular dysfunction;FunDO |
Disease | Obesity;FunDO |
Disease | Anorexia nervosa;FunDO |
Disease | polycystic ovary syndrome;GAD |
Disease | endometrial cancer;GAD |
Disease | bone density dihydrotestosterone estradiol sex hormone binding globulin testosterone;GAD |
Disease | Protein-energy malnutrition;FunDO |
|
External Links |
|
Links to Entrez Gene | 6462 |
Links to all GeneRIF Items | 6462 |
Links to iHOP | 6462 |
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Sequence Information |
|
Nucleotide Sequence |
>6462 : length: 1209 atggagagcagaggcccactggctacctcgcgcctgctgctgttgctgctgttgctacta ctgcgtcacacccgccagggatgggccctgagacctgttctccccacccagagtgcccac gaccctccggctgtccacctcagcaatggcccaggacaagagcctatcgctgtcatgacc tttgacctcaccaagatcacaaaaacctcctcctcctttgaggttcgaacctgggaccca gagggagtgattttttatggggataccaaccctaaggatgactggtttatgctgggactt cgagacggcaggcctgagatccaactgcacaatcactgggcccagcttacggtgggtgct ggaccacggctggatgatgggagatggcaccaggtggaagtcaagatggagggggactct gtgctgctggaggtggatggggaggaggtgctgcgcctgagacaggtctctgggcccctg accagcaaacgccatcccatcatgaggattgcgcttggggggctgctcttccccgcttcc aaccttcggttgccgctggttcctgccctggatggctgcctgcgccgggattcctggctg gacaaacaggccgagatctcagcatctgcccccactagcctcagaagctgtgatgtagaa tcaaatcccgggatatttctccctccagggactcaggcagaattcaatctccgagacatt ccccagcctcatgcagagccctgggccttctctttggacctgggactcaagcaggcagca ggctcaggccacctccttgctcttgggacaccagagaacccatcttggctcagtctccac ctccaagatcaaaaggtggtgttgtcttctgggtcggggccagggctggatctgcccctg gtcttgggactccctcttcagctgaagctgagtatgtccagggtggtcttgagccaaggg tcgaagatgaaggcccttgccctgcctcccttaggcctggctcccctccttaacctctgg gccaagcctcaagggcgtctcttcctgggggctttaccaggagaagactcttccacctct ttttgcctgaatggcctttgggcacaaggtcagaggctggatgtggaccaggccctgaac agaagccatgagatctggactcacagctgcccccagagcccaggcaatggcactgacgct tcccattaa |
Protein Sequence |
>6462 : length: 402 MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMT FDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGA GPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPAS NLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDI PQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPL VLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTS FCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH |