| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 64881 |
Name | PCDH20 |
Synonym | PCDH13;protocadherin 20;PCDH20;protocadherin 20 |
Definition | protocadherin 13|protocadherin-13|protocadherin-20 |
Position | 13q21 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically." |
| More detail of all Human literatures about PCDH20 | |
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Pathways and Diseases |
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Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Cadherin signaling pathway;PANTHER;P00012 |
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External Links |
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Links to Entrez Gene | 64881 |
Links to all GeneRIF Items | 64881 |
Links to iHOP | 64881 |
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Sequence Information |
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Nucleotide Sequence |
>64881 : length: 2856 atgcgcggccgagggaatgcgcgcagctcacaggccctgggagtgagctggtgcccggcg acctggcacccgcgcctggatatggggcgtctacatcgtcccaggagcagcaccagctac aggaacctgccgcatctgtttctgtttttcctcttcgtgggacccttcagctgcctcggg agttacagccgggccaccgagcttctgtacagcctaaacgagggactacccgcgggggtg ctcatcggcagcctggccgaggacctgcggctgctgcccaggtctgcagggaggccggac ccgcagtcgcagctgccagagcgcaccggtgctgagtggaacccccctctctccttcagc ctggcctcccggggactgagtggccagtacgtgaccctagacaaccgctctggggagctg cacacttcagctcaggagatcgacagggaggccctgtgtgttgaagggggtggagggact gcgtggagcggcagcgtttccatctcctcctctccttctgactcttgtcttttgctgctg gatgtgcttgtcctgcctcaggaatacttcaggtttgtgaaggtgaagatcgccatcaga gacatcaatgacaacgccccgcagttccctgtttcccagatctcggtgtgggtcccggaa aatgcacctgtaaacacccgactggccatagagcatcctgctgtggacccagatgtaggc attaatggggtacagacctatcgcttactggactaccatggtatgttcaccctggacgtg gaggagaatgagaatggggagcgcaccccctacctaattgtcatgggtgctttggacagg gaaacccaggaccagtatgtgagcatcatcatagctgaggatggtgggtctccaccactt ttgggcagtgccactctcaccattggcatcagtgacattaatgacaattgccctctcttc acagactcacaaatcaatgtcactgtgtatgggaatgctacagtgggcaccccaattgca gctgtccaggctgtggataaagacttggggaccaatgctcaaattacttattcttacagt cagaaagttccacaagcatctaaggatttatttcacctggatgaaaacactggagtcatt aaacttttcagtaagattggaggaagtgttctggagtcccacaagctcaccatccttgct aatggaccaggctgcatccctgctgtaatcactgctcttgtgtccattattaaagttatt ttcagaccccctgaaattgtccctcgttacatagcaaacgagatagatggtgtggtttat ctgaaagaactggaacccgttaacactcccattgcgtttttcaccataagagatccagaa ggtaaatacaaggttaactgctacctggatggtgaagggccgtttaggttatcaccttac aaaccatacaataatgaatatttactagagaccacaaaacctatggactatgagctacag cagttctatgaagtagctgtggtggcttggaactctgagggatttcatgtcaaaagggtc attaaagtgcaacttttagatgacaatgataatgctccaattttccttcaacccttaata gaactaaccatcgaagagaacaactcacccaatgcctttttgactaagctgtatgctaca gatgccgacagcgaggagagaggccaagtttcatattttctgggacctgatgctccatca tatttttccttagacagtgtcacaggaattctgacagtttctactcagctggaccgagaa gagaaagaaaagtacagatacactgtcagagctgttgactgtgggaagccacccagagaa tcagtagccactgtggccctcacagtgttggataaaaatgacaacagtcctcggtttatc aacaaggacttcagcttttttgtgcctgaaaactttccaggctatggtgagattggagta attagtgtaacagatgctgacgctggacgaaatggatgggtcgccctctctgtggtgaac cagagtgatatttttgtcatagatacaggaaagggtatgctgagggctaaagtctctttg gacagagagcagcaaagctcctatactttgtgggttgaagctgttgatgggggtgagcct gccctctcctctacagcaaaaatcacaattctccttctagatatcaatgacaaccctcct cttgttttgtttcctcagtctaatatgtcttatctgttagtactgccttctactctgcca ggctccccggttacagaagtctatgctgtcgacaaagacacaggcatgaatgctgtcata gcttacagcatcatagggagaagaggtcctaggcctgagtccttcaggattgaccctaaa actggcaacattactttggaagaggcattgctgcagacagattatgggctccatcgctta ctggtgaaagtgagtgatcatggttatcccgagcctctccactccacagtcatggtgaac ctatttgtcaatgacactgtcagtaatgagagttacattgagagtcttttaagaaaagaa ccagagattaatatagaggagaaagaaccacaaatctcaatagaaccgactcataggaag gtagaatctgtgtcttgtatgcccaccttagtagctctgtctgtaataagcttgggttcc atcacactggtcacagggatgggcatatacatctgtttaaggaaaggggaaaagcatccc agggaagatgaaaatttggaagtacagattccactgaaaggaaaaattgacttgcatatg cgagagagaaagccaatggatatttctaatatttga |
Protein Sequence |
>64881 : length: 951 MRGRGNARSSQALGVSWCPATWHPRLDMGRLHRPRSSTSYRNLPHLFLFFLFVGPFSCLG SYSRATELLYSLNEGLPAGVLIGSLAEDLRLLPRSAGRPDPQSQLPERTGAEWNPPLSFS LASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVSISSSPSDSCLLLL DVLVLPQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVG INGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPL LGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYS QKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAVITALVSIIKVI FRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDGEGPFRLSPY KPYNNEYLLETTKPMDYELQQFYEVAVVAWNSEGFHVKRVIKVQLLDDNDNAPIFLQPLI ELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYFSLDSVTGILTVSTQLDRE EKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGV ISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEP ALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAVI AYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVN LFVNDTVSNESYIESLLRKEPEINIEEKEPQISIEPTHRKVESVSCMPTLVALSVISLGS ITLVTGMGIYICLRKGEKHPREDENLEVQIPLKGKIDLHMRERKPMDISNI |