| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 650 |
Name | BMP2 |
Synonym | BDA2|BMP2A;bone morphogenetic protein 2;BMP2;bone morphogenetic protein 2 |
Definition | BMP-2A|bone morphogenetic protein 2A |
Position | 20p12 |
Gene Type | protein-coding |
|
PAH Type |
Description |
HPH | Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension. |
HPH | [The role of bone morphogenetic protein-2 in the pathogenesis of hypoxic pulmonary hypertension]. |
HPH | Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension. |
PAH | Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells. |
PAH | An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension. |
PH | An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension. |
| More detail of all Rat literatures about BMP2 | |
|
Pathways and Diseases |
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Pathway | Signaling by BMP;PID Reactome;500592 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Signaling by BMP;Reactome;REACT:12034 |
Pathway | TGF-beta signaling pathway;PANTHER;P00052 |
Pathway | BMP Signalling Pathway;BioCyc;PWY66-11 |
Pathway | Basal cell carcinoma;KEGG PATHWAY;hsa05217 |
Pathway | Hedgehog signaling pathway;KEGG PATHWAY;hsa04340 |
Pathway | TGF-beta signaling pathway;KEGG PATHWAY;hsa04350 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | alk in cardiac myocytes;PID BioCarta;100244 |
Disease | Height;NHGRI |
Disease | DEVELOPMENTAL;GAD |
Disease | Gouts;FunDO |
Disease | Amnionitis;FunDO |
Disease | Ankylosis;FunDO |
Disease | Osteoporosis;FunDO |
Disease | Body mass index;GAD |
Disease | Body mass index;NHGRI |
Disease | HFE hemochromatosis, modifier of;OMIM |
Disease | Cancer;FunDO |
Disease | METABOLIC;GAD |
Disease | iron burden;GAD |
Disease | height;GAD |
Disease | Hypertension, Pulmonary;FunDO |
|
External Links |
|
Links to Entrez Gene | 650 |
Links to all GeneRIF Items | 650 |
Links to iHOP | 650 |
|
Sequence Information |
|
Nucleotide Sequence |
>650 : length: 1191 atggtggccgggacccgctgtcttctagcgttgctgcttccccaggtcctcctgggcggc gcggctggcctcgttccggagctgggccgcaggaagttcgcggcggcgtcgtcgggccgc ccctcatcccagccctctgacgaggtcctgagcgagttcgagttgcggctgctcagcatg ttcggcctgaaacagagacccacccccagcagggacgccgtggtgcccccctacatgcta gacctgtatcgcaggcactcaggtcagccgggctcacccgccccagaccaccggttggag agggcagccagccgagccaacactgtgcgcagcttccaccatgaagaatctttggaagaa ctaccagaaacgagtgggaaaacaacccggagattcttctttaatttaagttctatcccc acggaggagtttatcacctcagcagagcttcaggttttccgagaacagatgcaagatgct ttaggaaacaatagcagtttccatcaccgaattaatatttatgaaatcataaaacctgca acagccaactcgaaattccccgtgaccagacttttggacaccaggttggtgaatcagaat gcaagcaggtgggaaagttttgatgtcacccccgctgtgatgcggtggactgcacaggga cacgccaaccatggattcgtggtggaagtggcccacttggaggagaaacaaggtgtctcc aagagacatgttaggataagcaggtctttgcaccaagatgaacacagctggtcacagata aggccattgctagtaacttttggccatgatggaaaagggcatcctctccacaaaagagaa aaacgtcaagccaaacacaaacagcggaaacgccttaagtccagctgtaagagacaccct ttgtacgtggacttcagtgacgtggggtggaatgactggattgtggctcccccggggtat cacgccttttactgccacggagaatgcccttttcctctggctgatcatctgaactccact aatcatgccattgttcagacgttggtcaactctgttaactctaagattcctaaggcatgc tgtgtcccgacagaactcagtgctatctcgatgctgtaccttgacgagaatgaaaaggtt gtattaaagaactatcaggacatggttgtggagggttgtgggtgtcgctag |
Protein Sequence |
>650 : length: 396 MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSM FGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEE LPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPA TANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVS KRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHP LYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKAC CVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR |