Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6988

Name

TCTA

Synonym

-;T-cell leukemia translocation altered;TCTA;T-cell leukemia translocation altered

Definition

T-cell leukemia translocation-altered gene protein|T-cell leukemia translocation-associated gene protein

Position

3p21

Gene Type

protein-coding

PAH Type

Description

PAH

"We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically."
More detail of all Human literatures about TCTA

External Links

Links to Entrez Gene

6988

Links to all GeneRIF Items

6988

Links to iHOP

6988

Sequence Information

Nucleotide Sequence

>6988 : length: 312
atggcggagtcctggtctgggcaggccttgcaggctctgccggccacggtgctgggcgcg
ctgggcagcgagttcttgcgggagtgggaggcgcaggacatgcgcgtgaccctcttcaag
ctgctgctgctgtggttggtgttaagtctcctgggcatccagctggcgtgggggttctac
gggaatacagtgaccgggttgtatcaccgtccaggtctgggtggtcagaatggatccacg
cctgatggctccacgcatttcccttcgtgggaaatggcagcaaacgaacctctcaaaacc
cacagagaataa

Protein Sequence

>6988 : length: 103
MAESWSGQALQALPATVLGALGSEFLREWEAQDMRVTLFKLLLLWLVLSLLGIQLAWGFY
GNTVTGLYHRPGLGGQNGSTPDGSTHFPSWEMAANEPLKTHRE



')