| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 7057 |
Name | THBS1 |
Synonym | THBS|THBS-1|TSP|TSP-1|TSP1;thrombospondin 1;THBS1;thrombospondin 1 |
Definition | thrombospondin-1|thrombospondin-1p180 |
Position | 15q15 |
Gene Type | protein-coding |
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PAH Type |
Description |
HPH | "The expression of TSP-1 appears to be increased in hypoxic pulmonary hypertension rats, which may contribute to the pathogenesis of hypoxic pulmonary vascular remodeling." |
| More detail of all Rat literatures about THBS1 | |
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Pathways and Diseases |
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Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Malaria;KEGG PATHWAY;hsa05144 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | Integrin cell surface interactions;PID Reactome;500004 |
Pathway | Integrin cell surface interactions;Reactome;REACT:13552 |
Pathway | p53 pathway;PANTHER;P00059 |
Pathway | Syndecan-4-mediated signaling events;PID Curated;200115 |
Pathway | ECM-receptor interaction;KEGG PATHWAY;hsa04512 |
Pathway | p53 signaling pathway;KEGG PATHWAY;hsa04115 |
Pathway | TGF-beta signaling pathway;KEGG PATHWAY;hsa04350 |
Pathway | Phagosome;KEGG PATHWAY;hsa04145 |
Pathway | Bladder cancer;KEGG PATHWAY;hsa05219 |
Disease | brain hemorrhage;GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Stroke;GAD |
Disease | myocardial infarct;GAD |
Disease | stroke, lacunar;GAD |
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External Links |
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Links to Entrez Gene | 7057 |
Links to all GeneRIF Items | 7057 |
Links to iHOP | 7057 |
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Sequence Information |
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Nucleotide Sequence |
>7057 : length: 3513 atggggctggcctggggactaggcgtcctgttcctgatgcatgtgtgtggcaccaaccgc attccagagtctggcggagacaacagcgtgtttgacatctttgaactcaccggggccgcc cgcaaggggtctgggcgccgactggtgaagggccccgacccttccagcccagctttccgc atcgaggatgccaacctgatcccccctgtgcctgatgacaagttccaagacctggtggat gctgtgcgggcagaaaagggtttcctccttctggcatccctgaggcagatgaagaagacc cggggcacgctgctggccctggagcggaaagaccactctggccaggtcttcagcgtggtg tccaatggcaaggcgggcaccctggacctcagcctgaccgtccaaggaaagcagcacgtg gtgtctgtggaagaagctctcctggcaaccggccagtggaagagcatcaccctgtttgtg caggaagacagggcccagctgtacatcgactgtgaaaagatggagaatgctgagttggac gtccccatccaaagcgtcttcaccagagacctggccagcatcgccagactccgcatcgca aaggggggcgtcaatgacaatttccagggggtgctgcagaatgtgaggtttgtctttgga accacaccagaagacatcctcaggaacaaaggctgctccagctctaccagtgtcctcctc acccttgacaacaacgtggtgaatggttccagccctgccatccgcactaactacattggc cacaagacaaaggacttgcaagccatctgcggcatctcctgtgatgagctgtccagcatg gtcctggaactcaggggcctgcgcaccattgtgaccacgctgcaggacagcatccgcaaa gtgactgaagagaacaaagagttggccaatgagctgaggcggcctcccctatgctatcac aacggagttcagtacagaaataacgaggaatggactgttgatagctgcactgagtgtcac tgtcagaactcagttaccatctgcaaaaaggtgtcctgccccatcatgccctgctccaat gccacagttcctgatggagaatgctgtcctcgctgttggcccagcgactctgcggacgat ggctggtctccatggtccgagtggacctcctgttctacgagctgtggcaatggaattcag cagcgcggccgctcctgcgatagcctcaacaaccgatgtgagggctcctcggtccagaca cggacctgccacattcaggagtgtgacaagagatttaaacaggatggtggctggagccac tggtccccgtggtcatcttgttctgtgacatgtggtgatggtgtgatcacaaggatccgg ctctgcaactctcccagcccccagatgaacgggaaaccctgtgaaggcgaagcgcgggag accaaagcctgcaagaaagacgcctgccccatcaatggaggctggggtccttggtcacca tgggacatctgttctgtcacctgtggaggaggggtacagaaacgtagtcgtctctgcaac aaccccacaccccagtttggaggcaaggactgcgttggtgatgtaacagaaaaccagatc tgcaacaagcaggactgtccaattgatggatgcctgtccaatccctgctttgccggcgtg aagtgtactagctaccctgatggcagctggaaatgtggtgcttgtccccctggttacagt ggaaatggcatccagtgcacagatgttgatgagtgcaaagaagtgcctgatgcctgcttc aaccacaatggagagcaccggtgtgagaacacggaccccggctacaactgcctgccctgc cccccacgcttcaccggctcacagcccttcggccagggtgtcgaacatgccacggccaac aaacaggtgtgcaagccccgtaacccctgcacggatgggacccacgactgcaacaagaac gccaagtgcaactacctgggccactatagcgaccccatgtaccgctgcgagtgcaagcct ggctacgctggcaatggcatcatctgcggggaggacacagacctggatggctggcccaat gagaacctggtgtgcgtggccaatgcgacttaccactgcaaaaaggataattgccccaac cttcccaactcagggcaggaagactatgacaaggatggaattggtgatgcctgtgatgat gacgatgacaatgataaaattccagatgacagggacaactgtccattccattacaaccca gctcagtatgactatgacagagatgatgtgggagaccgctgtgacaactgtccctacaac cacaacccagatcaggcagacacagacaacaatggggaaggagacgcctgtgctgcagac attgatggagacggtatcctcaatgaacgggacaactgccagtacgtctacaatgtggac cagagagacactgatatggatggggttggagatcagtgtgacaattgccccttggaacac aatccggatcagctggactctgactcagaccgcattggagatacctgtgacaacaatcag gatattgatgaagatggccaccagaacaatctggacaactgtccctatgtgcccaatgcc aaccaggctgaccatgacaaagatggcaagggagatgcctgtgaccacgatgatgacaac gatggcattcctgatgacaaggacaactgcagactcgtgcccaatcccgaccagaaggac tctgacggcgatggtcgaggtgatgcctgcaaagatgattttgaccatgacagtgtgcca gacatcgatgacatctgtcctgagaatgttgacatcagtgagaccgatttccgccgattc cagatgattcctctggaccccaaagggacatcccaaaatgaccctaactgggttgtacgc catcagggtaaagaactcgtccagactgtcaactgtgatcctggactcgctgtaggttat gatgagtttaatgctgtggacttcagtggcaccttcttcatcaacaccgaaagggacgat gactatgctggatttgtctttggctaccagtccagcagccgcttttatgttgtgatgtgg aagcaagtcacccagtcctactgggacaccaaccccacgagggctcagggatactcgggc ctttctgtgaaagttgtaaactccaccacagggcctggcgagcacctgcggaacgccctg tggcacacaggaaacacccctggccaggtgcgcaccctgtggcatgaccctcgtcacata ggctggaaagatttcaccgcctacagatggcgtctcagccacaggccaaagacgggtttc attagagtggtgatgtatgaagggaagaaaatcatggctgactcaggacccatctatgat aaaacctatgctggtggtagactagggttgtttgtcttctctcaagaaatggtgttcttc tctgacctgaaatacgaatgtagagatccctaa |
Protein Sequence |
>7057 : length: 1170 MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD VPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLL TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK VTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSN ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQT RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE TKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQI CNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACF NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKN AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPN LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN DGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRF QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD KTYAGGRLGLFVFSQEMVFFSDLKYECRDP |