Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7223

Name

TRPC4

Synonym

HTRP-4|HTRP4|TRP4;transient receptor potential cation channel, subfamily C, member 4;TRPC4;transient receptor potential cation channel, subfamily C, member 4

Definition

short transient receptor potential channel 4|trp-related protein 4

Position

13q13.3

Gene Type

protein-coding

PAH Type

Description

PAH

Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension.
More detail of all Human literatures about TRPC4

Pathways and Diseases

Pathway

Axon guidance;Reactome;REACT:18266

Pathway

Alzheimer disease-presenilin pathway;PANTHER;P00004

Disease

Renal Cell cancer;FunDO

Disease

Hypertension, Pulmonary;FunDO

External Links

Links to Entrez Gene

7223

Links to all GeneRIF Items

7223

Links to iHOP

7223

Sequence Information

Nucleotide Sequence

>7223 : length: 2682
atggctcagttctattacaaaagaaatgttaatgctccctatagagaccgcatccctcta
aggatagtaagagcagaatcagaactctcgccatcagaaaaagcctacttgaatgctgtg
gaaaagggagattatgccagtgtcaagaaatccctagaggaagctgaaatttattttaaa
atcaatattaattgcattgatcctctcggaagaactgctctcctcattgcaattgaaaat
gagaacttggagctcatcgaactactcttaagctttaatgtctatgttggagatgctcta
ttacatgctatcagaaaagaagtcgtcggagctgttgagctgttattgaaccacaaaaaa
cctagtggagaaaaacaggtgcctcctatactccttgataagcagttctctgaattcact
ccagacattacaccaatcattttggcagcccatacaaataattatgagataataaaactc
ttggttcagaaaggagtctcagtgcctcgaccccacgaggtccgctgtaactgtgtggaa
tgcgtgtccagttcagatgtggacagcctccgtcactcacgctccagactcaacatctac
aaggccttggccagtccctctctcattgcactgtcaagcgaagatccttttctcacagcc
tttcagttaagttgggaacttcaggaactgagcaaggtggaaaatgaattcaagtcggag
tatgaagagctgtcacggcagtgcaaacaatttgctaaggacctactggatcagacgaga
agttccagagaactggaaatcattcttaattaccgagatgacaatagtctcatagaagaa
caaagtggaaatgatcttgcaagactaaaattggccattaagtaccgtcaaaaagagttt
gttgcccagcccaattgtcaacagctgctggcatctcgctggtacgatgagtttccaggc
tggaggagaagacactgggcagtgaagatggtgacatgtttcataataggacttcttttt
cctgtcttctctgtgtgctacctgatagctcccaaaagcccacttggactgttcatcagg
aagccatttatcaagtttatctgccacacagcctcctatttgacttttttgttcctgctg
ctgcttgcctctcagcacatcgacaggtcagacttgaacaggcaaggtccaccaccaacc
atcgtcgagtggatgatattaccgtgggtcctgggcttcatatggggagaaattaaacag
atgtgggatggcggacttcaggactacatccatgattggtggaatctaatggactttgta
atgaactccttatatttagcaacaatctccttgaaaattgttgcatttgtaaagtacagt
gcccttaatccacgagaatcatgggacatgtggcatcccactctggtggcagaggcttta
tttgctattgcaaacatcttcagttctctgcgtctgatctcactgtttactgcaaattct
cacctgggacctctgcaaatatctctgggaagaatgctcctggacattttgaagtttcta
ttcatatactgccttgtgttgctagcatttgcaaatggcctaaatcaattgtacttctat
tatgaagaaacgaaagggttaacctgcaaaggcataagatgtgaaaagcagaataatgca
ttttcaacgttatttgagacactgcagtccctgttttggtcaatatttgggctcatcaat
ttatatgtgaccaatgtcaaagcacagcatgaatttactgagtttgttggtgccaccatg
tttgggacatacaatgtcatctctctggttgttctactcaacatgttaatagctatgatg
aataattcttaccaactgattgctgaccatgcagatatagaatggaaatttgcacgaaca
aagctttggatgagttattttgaagaaggaggtactctgcctactcccttcaatgtcatc
ccgagccccaagtctctctggtacctgatcaaatggatctggacacacttgtgcaagaaa
aagatgagaagaaagccagaaagttttggaacaatagggaggcgagctgctgataacttg
agaagacatcaccaataccaagaagttatgaggaacctggtgaagcgatacgttgctgca
atgattagagatgctaaaactgaagaaggcctgaccgaagagaactttaaggaactaaag
caagacatttctagtttccgctttgaagtcctgggattactaagaggaagcaaactttcc
acaatacaatctgcgaatgcctcgaaggagtcttcaaattcggcagactcagatgaaaag
agtgatagcgaagaagaagttgctcgtcaacaggctgcaggaccacttgagagaaatatt
caactggaatctcgaggattagcttcacggggtgacctgagcattcccggtctcagtgaa
caatgtgtgttagtagaccatagagaaaggaatacggacacactggggttacaggtagga
aagagagtgtgtccattcaagtcagagaaggtggtggtggaggacacggttcctataata
ccaaaggagaaacatgcaaaagaagaggactctagtatagactatgatctaaacctccca
gacacagtcacccacgaagattacgtgaccacaagattgtga

Protein Sequence

>7223 : length: 893
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK
ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK
PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE
CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE
YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF
VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR
KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ
MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL
FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY
YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM
FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI
PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAA
MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSADSDEK
SDSEEEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVG
KRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHEDYVTTRL



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