Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7292

Name

TNFSF4

Synonym

CD134L|CD252|GP34|OX-40L|OX4OL|TXGP1;tumor necrosis factor (ligand) superfamily, member 4;TNFSF4;tumor necrosis factor (ligand) superfamily, member 4

Definition

CD134 ligand|OX40 antigen ligand|OX40L|TAX transcriptionally-activated glycoprotein 1|glycoprotein Gp34|tax-transcriptionally activated glycoprotein 1 (34kD)|tumor necrosis factor ligand superfamily member 4

Position

1q25

Gene Type

protein-coding

PAH Type

Description

PH

Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension.
More detail of all Mouse literatures about TNFSF4

Pathways and Diseases

Pathway

Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060

Disease

IMMUNE;GAD

Disease

Influenza;FunDO

Disease

Celiac Disease;GAD

Disease

CARDIOVASCULAR;GAD

Disease

Asthma;FunDO

Disease

Myocardial infarction, susceptibility to;OMIM

Disease

Systemic lupus erythematosus;NHGRI

Disease

systemic lupus erythematosus;GAD

Disease

myocardial infarct;GAD

Disease

Atherosclerosis;FunDO

External Links

Links to Entrez Gene

7292

Links to all GeneRIF Items

7292

Links to iHOP

7292

Sequence Information

Nucleotide Sequence

>7292 : length: 552
atggaaagggtccaacccctggaagagaatgtgggaaatgcagccaggccaagattcgag
aggaacaagctattgctggtggcctctgtaattcagggactggggctgctcctgtgcttc
acctacatctgcctgcacttctctgctcttcaggtatcacatcggtatcctcgaattcaa
agtatcaaagtacaatttaccgaatataagaaggagaaaggtttcatcctcacttcccaa
aaggaggatgaaatcatgaaggtgcagaacaactcagtcatcatcaactgtgatgggttt
tatctcatctccctgaagggctacttctcccaggaagtcaacattagccttcattaccag
aaggatgaggagcccctcttccaactgaagaaggtcaggtctgtcaactccttgatggtg
gcctctctgacttacaaagacaaagtctacttgaatgtgaccactgacaatacctccctg
gatgacttccatgtgaatggcggagaactgattcttatccatcaaaatcctggtgaattc
tgtgtcctttga

Protein Sequence

>7292 : length: 183
MERVQPLEENVGNAARPRFERNKLLLVASVIQGLGLLLCFTYICLHFSALQVSHRYPRIQ
SIKVQFTEYKKEKGFILTSQKEDEIMKVQNNSVIINCDGFYLISLKGYFSQEVNISLHYQ
KDEEPLFQLKKVRSVNSLMVASLTYKDKVYLNVTTDNTSLDDFHVNGGELILIHQNPGEF
CVL



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