Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

826

Name

CAPNS1

Synonym

30K|CALPAIN4|CANP|CANPS|CAPN4|CDPS|CSS1;calpain, small subunit 1;CAPNS1;calpain, small subunit 1

Definition

CANP small subunit|calcium-activated neutral proteinase small subunit|calcium-dependent protease small subunit 1|calcium-dependent protease, small subunit|calpain 4, small subunit (30K)|calpain regulatory subunit|calpain small subunit 1|calpain, small pol

Position

19q13.12

Gene Type

protein-coding

PAH Type

Description

PH

"Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease."
More detail of all Mouse literatures about CAPNS1

Pathways and Diseases

Pathway

mcalpain and friends in cell motility;PID BioCarta;100111

Pathway

ucalpain and friends in cell spread;PID BioCarta;100008

Pathway

Huntington disease;PANTHER;P00029

Pathway

role of mef2d in t-cell apoptosis;PID BioCarta;100109

External Links

Links to Entrez Gene

826

Links to all GeneRIF Items

826

Links to iHOP

826

Sequence Information

Nucleotide Sequence

>826 : length: 807
atgttcctggttaactcgttcttgaagggcggcggcggcggcggcgggggaggcgggggc
ctgggtgggggcctgggaaatgtgcttggaggcctgatcagcggggccgggggcggcggc
ggcggcggcggcggcggcggcggtggtggaggcggcggtggcggtggaacggccatgcgc
atcctaggcggagtcatcagcgccatcagcgaggcggctgcgcagtacaacccggagccc
ccgcccccacgcacacattactccaacattgaggccaacgagagtgaggaggtccggcag
ttccggagactctttgcccagctggctggagatgacatggaggtcagcgccacagaactc
atgaacattctcaataaggttgtgacacgacaccctgatctgaagactgatggttttggc
attgacacatgtcgcagcatggtggccgtgatggatagcgacaccacaggcaagctgggc
tttgaggaattcaagtacttgtggaacaacatcaaaaggtggcaggccatatacaaacag
ttcgacactgaccgatcagggaccatttgcagtagtgaactcccaggtgcctttgaggca
gcagggttccacctgaatgagcatctctataacatgatcatccgacgctactcagatgaa
agtgggaacatggattttgacaacttcatcagctgcttggtcaggctggacgccatgttc
cgtgccttcaaatctcttgacaaagatggcactggacaaatccaggtgaacatccaggag
tggctgcagctgactatgtattcctga

Protein Sequence

>826 : length: 268
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR
ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL
MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ
FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF
RAFKSLDKDGTGQIQVNIQEWLQLTMYS



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