Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8862

Name

APLN

Synonym

APEL|XNPEP2;apelin;APLN;apelin

Definition

AGTRL1 ligand|APJ endogenous ligand

Position

Xq25

Gene Type

protein-coding

PAH Type

Description

HPH

Physical exercise decreased apelin expression and elevated APJ expression in pulmonary tissues of rats with hypoxic pulmonary hypertension.
More detail of all Rat literatures about APLN

Pathways and Diseases

Pathway

Signaling by GPCR;Reactome;REACT:14797

Pathway

Peptide ligand-binding receptors;PID Reactome;500405

Disease

Obesity;FunDO

Disease

Brain tumor;FunDO

Disease

Breast cancer;FunDO

Disease

Diabetes mellitus;FunDO

Disease

Pre-Eclampsia;FunDO

External Links

Links to Entrez Gene

8862

Links to all GeneRIF Items

8862

Links to iHOP

8862

Sequence Information

Nucleotide Sequence

>8862 : length: 234
atgaatctgcggctctgcgtgcaggcgctcctgctgctctggctctccttgaccgcggtg
tgtggagggtccctgatgccgcttcccgatgggaatgggctggaagacggcaatgtccgc
cacctggtgcagcccagagggtcaaggaatgggccagggccctggcagggaggtcggagg
aaattccgccgccagcggccccgcctctcccataagggacccatgcctttctga

Protein Sequence

>8862 : length: 77
MNLRLCVQALLLLWLSLTAVCGGSLMPLPDGNGLEDGNVRHLVQPRGSRNGPGPWQGGRR
KFRRQRPRLSHKGPMPF



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