| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 9034 |
Name | CCRL2 |
Synonym | CKRX|CRAM|CRAM-A|CRAM-B|HCR;chemokine (C-C motif) receptor-like 2;CCRL2;chemokine (C-C motif) receptor-like 2 |
Definition | C-C chemokine receptor-like 2|chemokine receptor CCR11|chemokine receptor X|putative MCP-1 chemokine receptor |
Position | 3p21 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically." |
| More detail of all Human literatures about CCRL2 | |
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Pathways and Diseases |
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Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Disease | IMMUNE;GAD |
Disease | Celiac Disease;GAD |
Disease | Rheumatoid arthritis;FunDO |
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External Links |
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Links to Entrez Gene | 9034 |
Links to all GeneRIF Items | 9034 |
Links to iHOP | 9034 |
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Sequence Information |
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Nucleotide Sequence |
>9034 : length: 1071 atgatctacacccgtttcttaaaaggcagtctgaagatggccaattacacgctggcacca gaggatgaatatgatgtcctcatagaaggtgaactggagagcgatgaggcagagcaatgt gacaagtatgacgcccaggcactctcagcccagctggtgccatcactctgctctgctgtg tttgtgatcggtgtcctggacaatctcctggttgtgcttatcctggtaaaatataaagga ctcaaacgcgtggaaaatatctatcttctaaacttggcagtttctaacttgtgtttcttg cttaccctgcccttctgggctcatgctgggggcgatcccatgtgtaaaattctcattgga ctgtacttcgtgggcctgtacagtgagacatttttcaattgccttctgactgtgcaaagg tacctagtgtttttgcacaagggaaactttttctcagccaggaggagggtgccctgtggc atcattacaagtgtcctggcatgggtaacagccattctggccactttgcctgaattcgtg gtttataaacctcagatggaagaccagaaatacaagtgtgcatttagcagaactcccttc ctgccagctgatgagacattctggaagcattttctgactttaaaaatgaacatttcggtt cttgtcctccccctatttatttttacatttctctatgtgcaaatgagaaaaacactaagg ttcagggagcagaggtatagccttttcaagcttgtttttgccataatggtagtcttcctt ctgatgtgggcgccctacaatattgcatttttcctgtccactttcaaagaacacttctcc ctgagtgactgcaagagcagctacaatctggacaaaagtgttcacatcactaaactcatc gccaccacccactgctgcatcaaccctctcctgtatgcgtttcttgatgggacatttagc aaatacctctgccgctgtttccatctgcgtagtaacaccccacttcaacccagggggcag tctgcacaaggcacatcgagggaagaacctgaccattccaccgaagtgtaa |
Protein Sequence |
>9034 : length: 356 MIYTRFLKGSLKMANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAV FVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIG LYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFV VYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLR FREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLI ATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV |