| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3037 |
Name | HAS2 |
Synonymous | -;hyaluronan synthase 2;HAS2;hyaluronan synthase 2 |
Definition | HA synthase 2|hyaluronate synthase 2|hyaluronic acid synthase 2 |
Position | 8q24.12 |
Gene Type | protein-coding |
Gene Mutation: | GWAS results PAH samples Lung cancer |
GWAS results [Top] | ||
|
Variant (Location; Chr; Position; SNP; Allele; Homogeneity) |
Discovery Cohort (Cochran-Armitage Trend Test P-value; P-value from Eigenstrat; MAF cases; MAF controls) |
Replication Cohort (Cochran-Armitage Trend Test P-value; MAF cases; MAF controls) |
|---|---|---|
flanking_3UTR; chr8;122399652;rs13267240;C/T; + + |
1.3472e10-3; 6.2847e10-4; 0.225; 0.1704 | 0.3949; 0.2394; 0.2204 |
Lung cancer [Top] | ||
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
p.P449P; chr8:122626661-122626661 |
lung | adenocarcinoma; carcinoma |
p.S143*; chr8:122641153-122641153 |
lung | adenocarcinoma; carcinoma |
p.N150Y; chr8:122641133-122641133 |
lung | adenocarcinoma; carcinoma |
p.P112H; chr8:122641246-122641246 |
lung | squamous_cell_carcinoma; carcinoma |
p.T352T; chr8:122626952-122626952 |
lung | adenocarcinoma; carcinoma |
p.L518F; chr8:122626456-122626456 |
lung | adenocarcinoma; carcinoma |
p.T172T; chr8:122641065-122641065 |
lung | squamous_cell_carcinoma; carcinoma |
p.R400Q; chr8:122626809-122626809 |
lung | adenocarcinoma; carcinoma |
p.A197V; chr8:122640991-122640991 |
lung | squamous_cell_carcinoma; carcinoma |
p.S257R; chr8:122627237-122627237 |
lung | adenocarcinoma; carcinoma |
p.W187*; chr8:122641020-122641020 |
lung | adenocarcinoma; carcinoma |
p.M138I; chr8:122641167-122641167 |
lung | adenocarcinoma; carcinoma |
p.P449P; chr8:122626661-122626661 |
lung | adenocarcinoma; carcinoma |
p.V210F; chr8:122629446-122629446 |
lung | adenocarcinoma; carcinoma |
p.P78H; chr8:122641348-122641348 |
lung | small_cell_carcinoma; carcinoma |
p.W404L; chr8:122626797-122626797 |
lung | adenocarcinoma; carcinoma |
p.I58M; chr8:122641407-122641407 |
lung | adenocarcinoma; carcinoma |
p.F52I; chr8:122641427-122641427 |
lung | squamous_cell_carcinoma; carcinoma |
p.S55S; chr8:122641416-122641416 |
lung | squamous_cell_carcinoma; carcinoma |
p.W354C; chr8:122626946-122626946 |
lung | adenocarcinoma; carcinoma |
p.V481L; chr8:122626567-122626567 |
lung | adenocarcinoma; carcinoma |
p.M130I; chr8:122641191-122641191 |
lung | adenocarcinoma; carcinoma |
p.E94D; chr8:122641299-122641299 |
lung | small_cell_carcinoma; carcinoma |
p.Q35*; chr8:122641478-122641478 |
lung | adenocarcinoma; carcinoma |