| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5617 |
Name | PRL |
Synonymous | -;prolactin;PRL;prolactin |
Definition | decidual prolactin |
Position | 6p22.2-p21.3 |
Gene Type | protein-coding |
Gene Mutation: | GWAS results PAH samples Lung cancer |
GWAS results [Top] | ||
|
Variant (Location; Chr; Position; SNP; Allele; Homogeneity) |
Discovery Cohort (Cochran-Armitage Trend Test P-value; P-value from Eigenstrat; MAF cases; MAF controls) |
Replication Cohort (Cochran-Armitage Trend Test P-value; MAF cases; MAF controls) |
|---|---|---|
flanking_3UTR; chr6;22335396;rs6456474;A/G; + + |
2.5590e10-4; 1.7721e10-4; 0.2044; 0.1451 | 0.01414; 0.1866; 0.1386 |
Lung cancer [Top] | ||
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
p.L126P; chr6:22290518-22290518 |
lung | adenocarcinoma; carcinoma |
p.W119C; chr6:22290538-22290538 |
lung | adenocarcinoma; carcinoma |
p.T128R; chr6:22290512-22290512 |
lung | adenocarcinoma; carcinoma |
p.L155R; chr6:22290431-22290431 |
lung | adenocarcinoma; carcinoma |
p.A50S; chr6:22294694-22294694 |
lung | adenocarcinoma; carcinoma |
p.P94P; chr6:22292797-22292797 |
lung | adenocarcinoma; carcinoma |
p.V113F; chr6:22290558-22290558 |
lung | small_cell_carcinoma; carcinoma |
p.A187T; chr6:22287756-22287756 |
lung | small_cell_carcinoma; carcinoma |
p.T93T; chr6:22292800-22292800 |
lung | adenocarcinoma; carcinoma |
p.P176H; chr6:22287788-22287788 |
lung | adenocarcinoma; carcinoma |
p.L214L; chr6:22287673-22287673 |
lung | squamous_cell_carcinoma; carcinoma |
p.A82S; chr6:22292835-22292835 |
lung | squamous_cell_carcinoma; carcinoma |