| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 2101 |
Name | ESRRA |
Synonymous | ERR1|ERRa|ERRalpha|ESRL1|NR3B1;estrogen-related receptor alpha;ESRRA;estrogen-related receptor alpha |
Definition | ERR-alpha|estrogen receptor-like 1|estrogen-related nuclear receptor alpha|nuclear receptor subfamily 3 group B member 1|steroid hormone receptor ERR1 |
Position | 11q13 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for ESRRA | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
AhR(h) + ERR1(h) <==> AhR(h):ERR1(h) (binding) | ERR1(h) --> LTF(h) (DNA binding; transactivation). | ERR1(h) + PNRC2(h) <==> ERR1(h):PNRC2(h) (binding) | SRC-1(h) + ERR1(h) <==> SRC-1(h):ERR1(h) (binding) | ERR1(h) + prox1(h) <==> ERR1(h):prox1(h) (binding) | ERR1(h) + SHP(h) <==> ERR1(h):SHP(h) (binding) | ERR1(h) + MACF1(h) <==> ERR1(h):MACF1(h) (binding) | ERR1(h) + DA2B(h) <==> ERR1(h):DA2B(h) (binding) | ERR1(h) + deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(h) <==> ERR1(h):deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(h) (binding) | ERR1(h) + ERR3(h) <==> ERR1(h):ERR3(h) (binding) | SRC3(h) + ERR1(h) <==> SRC3(h):ERR1(h) (binding) | RIP140(h) + ERR1(h) <==> RIP140(h):ERR1(h) (binding) | DAX1(h) + ERR1(h) <==> DAX1(h):ERR1(h) (binding) | ERR3(h) + ERR1(h) <==> ERR1(h):ERR3(h) (binding) | S8(h) + ERR1(h) <==> S8(h):ERR1(h) (binding) | ERR1(h) --> SULT2A1(h) (DNA binding; transactivation). | LYST(h) + ERR1(h) <==> LYST(h):ERR1(h) (binding) | ERR1(h) --> Pdk4(m) (DNA binding; transactivation). | ESRRA(h) --> ERR1(h) (expression). | ERR1(h) --/ SV40 MLP(sv) (DNA binding; transrepression). | PGC-1(h) + ERR1(h) <==> PGC-1(h):ERR1(h) (binding) | TIF2(h) + ERR1(h) <==> TIF2(h):ERR1(h) (binding) | ERR1(h) --> LFER(m) (DNA binding). | ERR1(h) --> LTF(h) (DNA binding). | ERR1(h) + ATP --> ERR1(h){p} + ADP (phosphorylation) | ERR1(h) + ATP --ERK2(h)--> ERR1(h){p} + ADP (phosphorylation) | ERR1(h) + ATP --ERK1(h)--> ERR1(h){p} + ADP (phosphorylation) | ERR1(h) + ATP --AKT-1(h)--> ERR1(h){p} + ADP (phosphorylation) | ERR1(h) + ATP --AKT-2(h)--> ERR1(h){p} + ADP (phosphorylation) | ESRRA(h) --> ERR1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
116 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 119 | Phosphoserine. | Swiss-Prot 53.0 | 124 | Phosphoserine. | Swiss-Prot 53.0 | 119 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 124 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr11 |
Promoter: 63828120 - 63830120 | Agilent_014791 |
chr11 |
Promoter: 63828120 - 63830120 | GSE27584 |