| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 2643 |
Name | GCH1 |
Synonymous | DYT14|DYT5|DYT5a|GCH|GTP-CH-1|GTPCH1|HPABH4B;GTP cyclohydrolase 1;GCH1;GTP cyclohydrolase 1 |
Definition | GTP cyclohydrolase I|GTP-CH-I|dystonia 14|guanosine 5'-triphosphate cyclohydrolase I |
Position | 14q22.1-q22.2 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for GCH1 | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
GCH1(h) --> GTP cyclohydrolase I isoform-1(h) (expression). | GCH1(h) --> GTP cyclohydrolase I(h) (expression). | IFNgamma(h) --> GTP cyclohydrolase I(h) (increase of abundance) | GCH1(h) --> GTP cyclohydrolase I isoform-2(h) (expression). | GCH1(h) --> GTP cyclohydrolase I isoform-3(h) (expression). | GCH1(h) --> GTP cyclohydrolase I isoform-4(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
There is no record for GCH1 | |||
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr14 |
Promoter: 54438792 - 54440792 | Agilent_014791 |
chr14 |
Promoter: 54438792 - 54440792 | GSE27584 |
chr14 |
Promoter: 54438792 - 54440792 | GSE27584 |
chr14 |
Promoter: 54438792 - 54440792 | GSE27584 |
chr14 |
Promoter: 54438792 - 54440792 | GSE27584 |
chr14 |
Promoter: 54438792 - 54440792 | Agilent_014791_44K |