Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2852

Name

GPER

Synonymous

CEPR|CMKRL2|DRY12|FEG-1|GPCR-Br|GPR30|LERGU|LERGU2|LyGPR;G protein-coupled estrogen receptor 1;GPER;G protein-coupled estrogen receptor 1

Definition

G protein-coupled receptor 30|G-protein coupled estrogen receptor 1|G-protein coupled receptor 30|IL8-related receptor DRY12|chemoattractant receptor-like 2|chemokine receptor-like 2|constitutively expressed peptide-like receptor|flow-induced endothelial

Position

7p22.3

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

Link to UCSC genome

Matched SNP location

dbSNP ID

Regulatory information

chr7:1121844-1133451chr7:1123738-1123738rs4285396Single_Nucleotides|eQTL|ZFAND2A, Chromatin_Structure|DNase-seq|UrotsaUt189, Chromatin_Structure|FAIRE|Urotsa, Chromatin_Structure|FAIRE|UrotsaUt189, Chromatin_Structure|DNase-seq|Phte, Chromatin_Structure|DNase-seq|Chorion, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|DNase-seq|Urotsa, Chromatin_Structure|DNase-seq|H1hesc, Chromatin_Structure|DNase-seq|Gm12892, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|DNase-seq|Gm12891, Chromatin_Structure|DNase-seq|Medullo, Chromatin_Structure|DNase-seq|Hepatocytes, Chromatin_Structure|DNase-seq|T47d, Chromatin_Structure|DNase-seq|Gm19239, Chromatin_Structure|DNase-seq|Huh75, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|DNase-seq|Huh7, Chromatin_Structure|DNase-seq|8988t, Chromatin_Structure|DNase-seq|Hsmm, Chromatin_Structure|DNase-seq|Cll

Transcription Factors   [Top]

Regulation From TransFac database

GPER(h) --> GPR30(h) (expression).
GPR30(h) --> EGFR(h){p} (increase of phosphorylation)
GPR30(h) --> ERK1(h){p} (increase of phosphorylation)
GPR30(h) --> ERK2(h){p} (increase of phosphorylation)
GPER(h) --> GPR30(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for GPER

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 1091469 - 1093469GSE27584

chr7

Promoter: 1091469 - 1093469GSE27584


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