| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 29843 |
Name | SENP1 |
Synonymous | SuPr-2;SUMO1/sentrin specific peptidase 1;SENP1;SUMO1/sentrin specific peptidase 1 |
Definition | SUMO1/sentrin specific protease 1|sentrin-specific protease 1|sentrin/SUMO-specific protease SENP1 |
Position | 12q13.1 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
|
Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr12:48436681-48500091 | chr12:48486715-48486715 | rs11168404 | Single_Nucleotides|eQTL|ZNF641, Chromatin_Structure|DNase-seq|Aosmc |
|---|---|---|---|
Transcription Factors [Top] |
|
Regulation From TransFac database |
SENP1(h) --> senp1-isoform1(h) (expression). | IKK-gamma(h){sumo} --senp1-isoform1(h)--> sumo1(h) + IKK-gamma(h) (desumoylation) | senp1(h) --> kallikrein-3(h) (increase of abundance) | senp1(h) --> c-Jun(h) (increase of abundance) | SENP1(h) --> senp1(h) (expression). | Ca --> senp1(h) (increase of abundance) | RanGAP1(h){sumo} --senp1(h)--> RanGAP1(h) + SUMO1-NTF(h) (desumoylation) | RanGAP1(m){sumo2} --senp1(h)--> SUMO2-NTF(h) + RanGAP1(h) (desumoylation) | RanGAP1(m){sumo3} --senp1(h)--> RanGAP1(h) + sumo3-NTF(h) (desumoylation) | sumo1(m.s.) --senp1(h)--> sumo1-NTF(m.s.) + protein remnants (cleavage) | SUMO2(h) --senp1(h)--> protein remnants + SUMO2-NTF(h) (cleavage) | sumo3(h) --senp1(h)--> protein remnants + sumo3-NTF(h) (cleavage) | SENP1(h) --> senp1-isoform2(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for SENP1 | |||
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr12 |
Promoter: 46785408 - 46787408 | Agilent_014791 |
chr12 |
Promoter: 46785408 - 46787408 | GSE27584 |
chr12 |
Promoter: 46785408 - 46787408 | Agilent_014791_44K |