Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4134

Name

MAP4

Synonymous

-;microtubule-associated protein 4;MAP4;microtubule-associated protein 4

Definition

MAP-4

Position

3p21

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

Link to UCSC genome

Matched SNP location

dbSNP ID

Regulatory information

chr3:47892182-48130769chr3:47898307-47898307rs319680Single_Nucleotides|eQTL|C3orf75, Chromatin_Structure|DNase-seq|Helas3, Chromatin_Structure|FAIRE|Helas3
chr3:47892182-48130769chr3:47931984-47931984rs319685Single_Nucleotides|eQTL|MAP4, Chromatin_Structure|DNase-seq|Medullo, Chromatin_Structure|FAIRE|Medullo, Chromatin_Structure|DNase-seq|Hcm, Protein_Binding|ChIP-seq|CEBPB, Protein_Binding|ChIP-seq|RFX3
chr3:47892182-48130769chr3:47932274-47932274rs319684Single_Nucleotides|eQTL|MAP4, Chromatin_Structure|DNase-seq|Medullo, Chromatin_Structure|FAIRE|Medullo, Protein_Binding|ChIP-seq|RFX3
chr3:47892182-48130769chr3:47937072-47937072rs777015Single_Nucleotides|eQTL|MAP4, Single_Nucleotides|eQTL|ZNF589, Motifs|PWM|NF-AT, Chromatin_Structure|DNase-seq|Gm12865
chr3:47892182-48130769chr3:47939626-47939626rs184388Single_Nucleotides|eQTL|MAP4, Chromatin_Structure|DNase-seq|Jurkat
chr3:47892182-48130769chr3:47956506-47956506rs11707679Single_Nucleotides|eQTL|MAP4, Protein_Binding|ChIP-seq|SPI1
chr3:47892182-48130769chr3:47984824-47984824rs7619882Single_Nucleotides|eQTL|MAP4, Chromatin_Structure|DNase-seq|Gm06990, Protein_Binding|ChIP-seq|MEF2A
chr3:47892182-48130769chr3:47985361-47985361rs7653368Single_Nucleotides|eQTL|ZNF589, Motifs|Footprinting|MRF-2, Motifs|Footprinting|MRF-2, Motifs|PWM|MRF-2, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|FAIRE|Gm12878, Chromatin_Structure|FAIRE|Gm12891
chr3:47892182-48130769chr3:47999674-47999674rs2053767Single_Nucleotides|eQTL|MAP4, Motifs|PWM|Obox3, Motifs|PWM|Obox1, Motifs|PWM|EBF1, Chromatin_Structure|DNase-seq|Hrpe, Protein_Binding|ChIP-seq|RFX3
chr3:47892182-48130769chr3:48002640-48002640rs7374516Single_Nucleotides|eQTL|MAP4, Protein_Binding|ChIP-seq|RFX3, Protein_Binding|ChIP-seq|USF1, Protein_Binding|ChIP-seq|USF1, Protein_Binding|ChIP-seq|USF1
chr3:47892182-48130769chr3:48005673-48005673rs2166770Single_Nucleotides|eQTL|MAP4, Motifs|PWM|AR, Motifs|PWM|GR, Motifs|PWM|AR, Motifs|PWM|NR3C1, Chromatin_Structure|DNase-seq|Hsmmt, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|FAIRE|Gm12891
chr3:47892182-48130769chr3:48017617-48017617rs9814961Single_Nucleotides|eQTL|MAP4, Protein_Binding|ChIP-seq|RFX3
chr3:47892182-48130769chr3:48022573-48022573rs7426976Single_Nucleotides|eQTL|MAP4, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|DNase-seq|Hipe
chr3:47892182-48130769chr3:48099750-48099750rs7642590Single_Nucleotides|eQTL|MAP4, Motifs|PWM|Pou6f1, Motifs|PWM|Pou6f1, Motifs|PWM|Pax6, Chromatin_Structure|DNase-seq|Myometr, Chromatin_Structure|DNase-seq|Huvec, Chromatin_Structure|DNase-seq|Panisd, Chromatin_Structure|DNase-seq|Hsmm, Chromatin_Structure|DNase-seq|Hac, Chromatin_Structure|DNase-seq|Aoaf, Chromatin_Structure|DNase-seq|Hcfaa, Chromatin_Structure|DNase-seq|Hbmec, Chromatin_Structure|DNase-seq|Hmvecdblad, Chromatin_Structure|DNase-seq|Hmveclbl, Chromatin_Structure|DNase-seq|Ag09309, Chromatin_Structure|DNase-seq|Hmf, Chromatin_Structure|DNase-seq|Hae, Chromatin_Structure|FAIRE|K562, Chromatin_Structure|DNase-seq|Nhdfad, Chromatin_Structure|DNase-seq|Hffmyc, Chromatin_Structure|DNase-seq|Ag10803, Chromatin_Structure|DNase-seq|Hmvecdblneo, Chromatin_Structure|DNase-seq|Hipe, Chromatin_Structure|DNase-seq|Hvmf, Chromatin_Structure|DNase-seq|Hpaf, Chromatin_Structure|DNase-seq|Bj, Chromatin_Structure|DNase-seq|Ag09319, Chromatin_Structure|DNase-seq|Osteobl, Chromatin_Structure|DNase-seq|Fibrobl, Chromatin_Structure|DNase-seq|Fibrop, Chromatin_Structure|DNase-seq|Nhlf, Chromatin_Structure|DNase-seq|Phte, Chromatin_Structure|DNase-seq|Progfib

Transcription Factors   [Top]

Regulation From TransFac database

MAP4(h) --> map4(h) (expression).
MAP4(h) --> map4-isoform1(h) (expression).
MAP4(h) --> map4-isoform2(h) (expression).
MAP4(h) --> map4-isoform3(h) (expression).
MAP4(h) --> map4-isoform4(h) (expression).
MAP4(h) --> map4-isoform5(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

94Phosphoserine.Swiss-Prot 53.0
96Phosphothreonine.Swiss-Prot 53.0
97Phosphothreonine.Swiss-Prot 53.0
99Phosphoserine.Swiss-Prot 53.0
253Phosphoserine (By similarity).Swiss-Prot 53.0
280Phosphoserine.Swiss-Prot 53.0
484Phosphothreonine.Swiss-Prot 53.0
507Phosphoserine.Swiss-Prot 53.0
510Phosphoserine.Swiss-Prot 53.0
521Phosphothreonine.Swiss-Prot 53.0
571Phosphothreonine.Swiss-Prot 53.0
624Phosphoserine (By similarity).Swiss-Prot 53.0
627Phosphothreonine.Swiss-Prot 53.0
636Phosphoserine.Swiss-Prot 53.0
643Phosphoserine (By similarity).Swiss-Prot 53.0
696Phosphoserine.Swiss-Prot 53.0
787Phosphoserine.Swiss-Prot 53.0
811Phosphothreonine (By similarity).Swiss-Prot 53.0
825Phosphoserine.Swiss-Prot 53.0
827Phosphoserine.Swiss-Prot 53.0
874Phosphothreonine (By similarity).Swiss-Prot 53.0
1073Phosphoserine.Swiss-Prot 53.0
1151Phosphoserine.Swiss-Prot 53.0
696Phosphoserine (CDK1)9398320;11683421;15216889Phospho.ELM 6.0
787Phosphoserine (CDK1)9398320;11683421;15216889Phospho.ELM 6.0
521Phosphothreonine15302935;17081983Phospho.ELM 6.0
507Phosphoserine15302935;17081983Phospho.ELM 6.0
280Phosphoserine15302935;17081983Phospho.ELM 6.0
571Phosphothreonine15302935;17081983Phospho.ELM 6.0
99Phosphoserine17081983Phospho.ELM 6.0
358Phosphoserine17081983Phospho.ELM 6.0
510Phosphoserine17081983Phospho.ELM 6.0
627Phosphothreonine17081983Phospho.ELM 6.0
636Phosphoserine17081983Phospho.ELM 6.0
1151Phosphoserine17081983Phospho.ELM 6.0
825Phosphoserine16565220Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 48105215 - 48107215Agilent_014791

chr3

Promoter: 48105214 - 48107214GSE27584

chr3

Promoter: 48105215 - 48107215GSE27584

chr3

Promoter: 48105215 - 48107215Agilent_014791_44K


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