Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5739

Name

PTGIR

Synonymous

IP|PRIPR;prostaglandin I2 (prostacyclin) receptor (IP);PTGIR;prostaglandin I2 (prostacyclin) receptor (IP)

Definition

PGI receptor|PGI2 receptor|prostacyclin receptor|prostaglandin I2 receptor|prostanoid IP receptor

Position

19q13.3

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for PTGIR

Transcription Factors   [Top]

Regulation From TransFac database

IP(h) + n ATP --> IP(h){p}n + n ADP (phosphorylation)
IP(h) + ATP --> IP(h){pS358} + ADP (phosphorylation)
PTGIR(h) --> IP(h) (expression).
PGE2 + IP(h) <==> PGE2:IP(h) (binding)
prostaglandin D2 + IP(h) <==> prostaglandin D2:IP(h) (binding)
prostaglandin F2-alpha + IP(h) <==> prostaglandin F2-alpha:IP(h) (binding)
PTGIR(h) --> IP(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

7N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
308S-palmitoyl cysteine.Swiss-Prot 53.0
311S-palmitoyl cysteine.Swiss-Prot 53.0
383Cysteine methyl ester.Swiss-Prot 53.0
383S-farnesyl cysteine.Swiss-Prot 53.0
328Phosphoserine (PKC alpha)9722557Phospho.ELM 6.0

Methylation Profile   [Top]

There is no record for PTGIR



')