Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7049

Name

TGFBR3

Synonymous

BGCAN|betaglycan;transforming growth factor, beta receptor III;TGFBR3;transforming growth factor, beta receptor III

Definition

TGF-beta receptor type 3|TGF-beta receptor type III|TGFR-3|betaglycan proteoglycan|transforming growth factor beta receptor type 3

Position

1p33-p32

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for TGFBR3

Transcription Factors   [Top]

Regulation From TransFac database

TGFbeta1(h) + TGFbetaR-III(h) + TGFbetaR-II(h) <==> TGFbeta1(h):TGFbetaR-III(h):TGFbetaR-II(h) (binding)
TGFbeta3(h) + TGFbetaR-III(h) <==> TGFbeta3(h):TGFbetaR-III(h) (binding)
TGFbeta1(h) + TGFbetaR-III(h) <==> TGFbeta1(h):TGFbetaR-III(h) (binding)
TGFbeta2(h) + TGFbetaR-III(h) <==> TGFbeta2(h):TGFbetaR-III(h) (binding)
TGFbeta1(h):TGFbetaR-III(h):TGFbetaR-II(h) + TGFbetaR-I(h) <==> TGFbeta1(h):TGFbetaR-II(h):TGFbetaR-I(h) + TGFbetaR-III(h) (binding)
TGFBR3(h) --> TGFbetaR-III(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

141N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
491N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
533O-linked (Xyl...) (glycosaminoglycan) (Bysimilarity).Swiss-Prot 53.0
544O-linked (Xyl...) (glycosaminoglycan) (Bysimilarity).Swiss-Prot 53.0
570N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
589N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
696N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 92123743 - 92125743Agilent_014791

chr1

Promoter: 92123743 - 92125743GoldenGate_Methylation_Cancer_Panel_I

chr1

Promoter: 92123743 - 92125743GSE27584


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