Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8412

Name

BCAR3

Synonymous

NSP2|SH2D3B;breast cancer anti-estrogen resistance 3;BCAR3;breast cancer anti-estrogen resistance 3

Definition

SH2 domain-containing protein 3B|breast cancer anti-estrogen resistance protein 3|breast cancer antiestrogen resistance 3 protein|dJ1033H22.2 (breast cancer anti-estrogen resistance 3)|novel SH2-containing protein 2

Position

1p22.1

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

Link to UCSC genome

Matched SNP location

dbSNP ID

Regulatory information

chr1:94027347-94312706chr1:94097441-94097441rs399649Single_Nucleotides|eQTL|HSS00223805, Chromatin_Structure|DNase-seq|Ag04449, Chromatin_Structure|DNase-seq|Hae, Chromatin_Structure|DNase-seq|Hcf, Chromatin_Structure|DNase-seq|Hcm, Chromatin_Structure|DNase-seq|Hee, Chromatin_Structure|DNase-seq|Hpf, Chromatin_Structure|DNase-seq|Hsmm, Chromatin_Structure|DNase-seq|Be2c, Chromatin_Structure|DNase-seq|Hct116, Chromatin_Structure|DNase-seq|Hmvecdblad, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Wi38, Chromatin_Structure|DNase-seq|A549, Chromatin_Structure|DNase-seq|Hvmf, Chromatin_Structure|DNase-seq|Gm12891, Chromatin_Structure|DNase-seq|Huh7, Chromatin_Structure|DNase-seq|Ag10803, Chromatin_Structure|DNase-seq|Ag04450, Chromatin_Structure|DNase-seq|Hrce, Chromatin_Structure|DNase-seq|Hrpe, Chromatin_Structure|DNase-seq|Gm12892, Chromatin_Structure|FAIRE|K562, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Hrgec, Chromatin_Structure|DNase-seq|Helas3, Chromatin_Structure|DNase-seq|Hmvecdblneo, Chromatin_Structure|DNase-seq|Nhdfad, Chromatin_Structure|DNase-seq|Wi38, Chromatin_Structure|DNase-seq|Hipe, Chromatin_Structure|DNase-seq|Nhdfneo, Chromatin_Structure|DNase-seq|Hff, Chromatin_Structure|DNase-seq|Hgf, Chromatin_Structure|DNase-seq|Gm19239, Chromatin_Structure|DNase-seq|Hepg2, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Hmf, Chromatin_Structure|DNase-seq|Hmvecdneo, Chromatin_Structure|DNase-seq|H7es, Chromatin_Structure|DNase-seq|Hmveclbl, Chromatin_Structure|DNase-seq|Hmvecdlyneo, Chromatin_Structure|DNase-seq|Jurkat, Chromatin_Structure|DNase-seq|K562, Chromatin_Structure|FAIRE|Hepg2, Chromatin_Structure|DNase-seq|Ips, Chromatin_Structure|DNase-seq|Helas3Ifna4h, Chromatin_Structure|DNase-seq|Ag09309, Chromatin_Structure|DNase-seq|Ag09319, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|DNase-seq|Hconf, Chromatin_Structure|DNase-seq|Hffmyc, Chromatin_Structure|DNase-seq|Hnpce, Chromatin_Structure|DNase-seq|Hpdlf, Chromatin_Structure|DNase-seq|Werirb1, Chromatin_Structure|DNase-seq|Gm12865, Chromatin_Structure|DNase-seq|Hcpe, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|DNase-seq|Huh75, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|GATA2, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|GATA2, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|RAD21, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|SMC3, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|SMC3, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|GATA1, Protein_Binding|ChIP-seq|GATA1, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|RAD21, Protein_Binding|ChIP-seq|RAD21, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCFL, Protein_Binding|ChIP-seq|RAD21, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|GATA3, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|GATA2, Protein_Binding|ChIP-seq|SMC3, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|RAD21, Protein_Binding|ChIP-seq|RAD21, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF

Transcription Factors   [Top]

Regulation From TransFac database

ErbB2(h){pY1139} + BCAR-3(h) <==> ErbB2(h){pY1139}:BCAR-3(h) (binding)
ErbB3-isoform1(h){pY868} + BCAR-3(h) <==> ErbB3-isoform1(h){pY868}:BCAR-3(h) (binding)
ErbB4(h) + BCAR-3(h) <==> ErbB4(h):BCAR-3(h) (binding)
BCAR-3(h) + ThrRS(h) <==> BCAR-3(h):ThrRS(h) (binding)
BCAR-3(h) + PabpC1(h) <==> BCAR-3(h):PabpC1(h) (binding)
BCAR-3(h) + IMPDH2(h) <==> BCAR-3(h):IMPDH2(h) (binding)
BCAR-3(h) + ILRS(h) <==> BCAR-3(h):ILRS(h) (binding)
BCAR3(h) --> BCAR-3(h) (expression).
BCAR3(h) --> BCAR-3-isoform1(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

130Phosphothreonine.Swiss-Prot 53.0
182Phosphoserine.Swiss-Prot 53.0
370Phosphoserine (By similarity).Swiss-Prot 53.0
375Phosphoserine.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

 Promoter: 93919473 - 93921473Agilent_014791

chr1

 Promoter: 93919473 - 93921473GSE27584

chr1

 Promoter: 93919473 - 93921473Agilent_014791_44K

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