| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 94 |
Name | ACVRL1 |
Synonymous | ACVRLK1|ALK-1|ALK1|HHT|HHT2|ORW2|SKR3|TSR-I;activin A receptor type II-like 1;ACVRL1;activin A receptor type II-like 1 |
Definition | TGF-B superfamily receptor type I|activin A receptor, type II-like kinase 1|serine/threonine-protein kinase receptor R3 |
Position | 12q13.13 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for ACVRL1 | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
BMP6(h) + ALK-1(h) + ActR-II(m) <==> BMP6(h):ALK-1(h):ActR-II(m) (binding) | BMP6(h) + ALK-1(h) + ActR-IIB(m) <==> BMP6(h):ALK-1(h):ActR-IIB(m) (binding) | BMP6(h) + ALK-1(h) + BMPR-II(h) <==> BMP6(h):ALK-1(h):BMPR-II(h) (binding) | TGFbeta1(pg) + TGFbetaR-II(h) + ALK-1(h) <==> TGFbeta1(pg):TGFbetaR-II(h):ALK-1(h) (binding) | activin A(h) + ActR-II(h) + ALK-1(h) <==> activin A(h):ActR-II(h):ALK-1(h) (binding) | activin A(h) + ActR-IIB(h) + ALK-1(h) <==> activin A(h):ActR-IIB(h):ALK-1(h) (binding) | TGFbeta1(v.s.) + TGFbetaR-II(h) + ALK-1(h) <==> TGFbeta1(v.s.):TGFbetaR-II(h):ALK-1(h) (binding) | ALK-1(h) + LXR-beta(h) <==> ALK-1(h):LXR-beta(h) (binding) | ACVRL1(h) --> ALK-1(h) (expression). | Smad1(h) + NTP --ALK-1(h)--> Smad1(h){p} + NDP (phosphorylation) | LXR-beta(h) + NTP --ALK-1(h)--> LXR-beta(h){p} + NDP (phosphorylation) | ACVRL1(h) --> ALK-1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
98 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr12 |
Promoter: 50585969 - 50587969 | Agilent_014791 |
chr12 |
Promoter: 50585969 - 50587969 | GSE27584 |
chr12 |
Promoter: 50585969 - 50587969 | Agilent_014791_44K |