deTS Results for Other specified/unspecified soft tissue disorders

Traits Information:

Trait ID:

1007

M13_SOFTTISSUENAS
Other specified/unspecified soft tissue disorders
UK Biobank (UKBB)
Neale Lab, 2018
N/A
# cases = 2930 | # controls = 358264
# SNPs = 11108100 | # genes = 21891
1.022
p (gene) < 0.05:  # TAGs = 1377
p (gene) < 0.01:  # TAGs = 343
p (gene) < 0.001:  # TAGs = 45
p (gene) < 1.0E-4:  # TAGs = 3
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.5460.1210.7840.7310.1960.9670.9970.9670.9860.9510.9950.9980.9970.930.9670.9860.9510.9780.4810.1210.4160.1960.7310.4160.1960.01820.1560.2430.2430.2430.6730.2960.1210.4810.7840.2960.6730.02610.8310.6110.8290.9040.4160.6730.1210.9040.9670.2470.01740.7230.9530.6020.9030.9530.9940.8260.9530.9030.9940.9810.9030.9810.9940.7230.9810.1630.2470.3530.6020.2470.6020.03320.05970.2470.1020.7230.1630.6020.8260.1020.6020.9530.03320.1630.4740.6020.4740.7220.8260.2470.4740.2470.8260.9940.4460.06051.00.7860.7860.7861.01.01.01.01.01.00.7860.7861.00.7860.4460.7860.4460.7860.4460.4460.4460.7860.4460.7860.7860.4460.4460.4460.4460.7860.7860.4460.7860.01550.7861.00.7860.7861.01.00.06051.00.7861.00.786Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.9850.3250.4550.9250.8610.6520.8570.9460.8160.8610.8610.2720.2660.03030.1380.8960.390.390.1760.1380.8180.580.3290.05760.1360.1760.4550.3290.1380.7690.8570.6520.3290.2690.2690.4510.4550.4550.9250.390.8960.390.6520.1380.7990.2120.08260.4320.5610.5610.8830.7970.3110.5610.1370.4320.1350.1370.2130.6870.1370.6870.3130.4320.8850.1350.5610.01270.2120.5610.4320.5610.1370.2130.1350.4320.1370.2120.6860.2120.1370.7990.9430.9430.7990.4320.6870.4321.00.4440.4450.4451.00.7840.4431.01.01.00.1860.7840.7840.7840.01531.00.01530.4450.7840.1860.1860.4430.1860.1860.4440.4450.7841.00.4451.00.1850.4450.05990.7841.00.4440.1860.7841.00.05990.7840.7840.7840.445Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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