Trait Name |
Trait Full Name |
Panel |
Author |
Year |
Cases* |
Controls |
# TAG Sets |
Top 3 Tissues (GTEx): p (chi2) |
2 Hour Glucose | 2-Hour Glucose | Expanded Trait Collection (ETC) | Saxena | 2010 | 0 | 15234 | 3 | Pancreas: p = 0.00693 Pituitary: p = 0.03 Nerve - Tibial: p = 0.03 |
ADHD | Attention Deficit Hyperactivity Disorder | Expanded Trait Collection (ETC) | Demontis | 2017 | 19099 | 34194 | 5 | Brain - Anterior cingulate cortex (BA24): p = 8.4E-6 Brain - Frontal Cortex (BA9): p = 2.18E-5 Brain - Hippocampus: p = 3.47E-5 |
Age At Menarche | Age At Menarche | Expanded Trait Collection (ETC) | Perry | 2014 | 0 | 182413 | 4 | Brain - Cerebellum: p = 2.02E-4 Brain - Cerebellar Hemisphere: p = 3.28E-4 Brain - Caudate (basal ganglia): p = 0.00298 |
Age At Menopause | Age At Menopause | Expanded Trait Collection (ETC) | Day | 2015 | 0 | 2545 | 5 | Adrenal Gland: p = 0.01 Uterus: p = 0.02 Muscle - Skeletal: p = 0.03 |
Alzheimers | Alzheimer's Disease | Expanded Trait Collection (ETC) | Lambert | 2013 | 17008 | 37154 | 5 | Whole Blood: p = 2.47E-4 Pancreas: p = 0.00114 Lung: p = 0.00274 |
Clozapine Induced Agranulocytosis | Clozapine Induced Agranulocytosis | Expanded Trait Collection (ETC) | Goldstein | 2014 | 161 | 1196 | 3 | Whole Blood: p = 4.09E-4 Spleen: p = 0.02 Artery - Aorta: p = 0.07 |
Depressive Symptoms | Depressive Symptoms | Expanded Trait Collection (ETC) | Okbay | 2016 | 122210 | 58835 | 3 | Spleen: p = 0.00128 Uterus: p = 0.00882 Brain - Cerebellar Hemisphere: p = 0.02 |
Hemoglobin A1c | Hemoglobin A1c | Expanded Trait Collection (ETC) | Soranzo | 2010 | 0 | 46368 | 5 | Whole Blood: p = 3.25E-4 Liver: p = 7.21E-4 Adipose - Subcutaneous: p = 0.00569 |
Internalizing Problems | Internalizing Problems | Expanded Trait Collection (ETC) | Benke | 2014 | 0 | 4596 | 3 | Heart - Atrial Appendage: p = 0.00137 Heart - Left Ventricle: p = 0.00364 Adrenal Gland: p = 0.00377 |
MDD | Major Depressive Disorder | Expanded Trait Collection (ETC) | Wray | 2018 | 16823 | 25632 | 5 | Brain - Frontal Cortex (BA9): p = 0.00208 Uterus: p = 0.00276 Brain - Anterior cingulate cortex (BA24): p = 0.00294 |
Neuroticism Symptoms | Neuroticism Symptoms | Expanded Trait Collection (ETC) | Okbay | 2016 | 0 | 170911 | 5 | Brain - Frontal Cortex (BA9): p = 6.11E-4 Brain - Cortex: p = 0.00128 Brain - Nucleus accumbens (basal ganglia): p = 0.00128 |
Obsessive Compulsive Disorder | Obsessive Compulsive Disorder | Expanded Trait Collection (ETC) | Arnold | 2017 | 2688 | 7037 | 3 | Vagina: p = 0.00243 Colon - Sigmoid: p = 0.00333 Kidney - Cortex: p = 0.00333 |
Rheumatoid Arthritis | Rheumatoid Arthritis | Expanded Trait Collection (ETC) | Stahl | 2010 | 5539 | 20169 | 5 | Spleen: p = 3.62E-9 Small Intestine - Terminal Ileum: p = 2.06E-5 Lung: p = 2.85E-4 |
Subjective Well Being | Subjective Well Being | Expanded Trait Collection (ETC) | Okbay | 2016 | 0 | 298420 | 4 | Pituitary: p = 0.00147 Brain - Spinal cord (cervical c-1): p = 0.00761 Brain - Putamen (basal ganglia): p = 0.01 |
Type 2 Diabetes | Type 2 Diabetes | Expanded Trait Collection (ETC) | Morris | 2012 | 12171 | 56862 | 4 | Uterus: p = 7.0E-4 Adipose - Subcutaneous: p = 0.00117 Artery - Tibial: p = 0.00205 |
Anxiety | Anxiety Continuous | Expanded Trait Collection (ETC) | Otowa | 2016 | 0 | 18186 | 3 | Brain - Amygdala: p = 9.39E-4 Brain - Caudate (basal ganglia): p = 0.00157 Brain - Putamen (basal ganglia): p = 0.00157 |
Autism | Autism Europeans | Expanded Trait Collection (ETC) | Psychiatric-Genomics-Consortium | 2017 | 6197 | 7377 | 3 | Colon - Sigmoid: p = 0.00662 Minor Salivary Gland: p = 0.02 Brain - Spinal cord (cervical c-1): p = 0.02 |
Birth Weight | Birth Weight European | Expanded Trait Collection (ETC) | Horikoshi | 2016 | 0 | 133903 | 4 | Lung: p = 7.44E-4 Esophagus - Gastroesophageal Junction: p = 0.00118 Artery - Tibial: p = 0.00178 |
Blood Lipids | High Density Lipoprotein | Expanded Trait Collection (ETC) | Teslovich | 2010 | 0 | 99900 | 5 | Liver: p = 1.49E-6 Adipose - Subcutaneous: p = 2.49E-5 Adipose - Visceral (Omentum): p = 9.29E-5 |
Blood Lipids | Low Density Lipoprotein | Expanded Trait Collection (ETC) | Teslovich | 2010 | 0 | 95454 | 5 | Liver: p = 1.68E-9 Spleen: p = 3.54E-5 Kidney - Cortex: p = 0.00207 |
Blood Lipids | Total Cholesterol | Expanded Trait Collection (ETC) | Teslovich | 2010 | 0 | 100184 | 5 | Liver: p = 2.6E-12 Adrenal Gland: p = 4.85E-4 Spleen: p = 7.81E-4 |
Blood Lipids | Triglycerides | Expanded Trait Collection (ETC) | Teslovich | 2010 | 0 | 96598 | 5 | Liver: p = 8.35E-9 Adipose - Subcutaneous: p = 7.04E-4 Adipose - Visceral (Omentum): p = 8.71E-4 |
BMI | BMI European | Expanded Trait Collection (ETC) | Locke | 2015 | 0 | 234069 | 4 | Brain - Substantia nigra: p = 3.72E-5 Brain - Cerebellum: p = 1.92E-4 Brain - Hippocampus: p = 1.92E-4 |
Bone Mineral Density | Femoral Neck Bone Mineral Density | Expanded Trait Collection (ETC) | Zheng | 2015 | 0 | 26320 | 5 | Artery - Coronary: p = 5.32E-6 Artery - Aorta: p = 5.17E-4 Uterus: p = 5.93E-4 |
Bone Mineral Density | Forearm Bone Mineral Density | Expanded Trait Collection (ETC) | Zheng | 2015 | 0 | 6627 | 3 | Artery - Tibial: p = 2.0E-4 Pancreas: p = 5.75E-4 Prostate: p = 0.00207 |
Educational Attainment | Education Years All | Expanded Trait Collection (ETC) | Okbay | 2016 | 0 | 293723 | 4 | Brain - Putamen (basal ganglia): p = 1.07E-5 Brain - Caudate (basal ganglia): p = 2.86E-5 Brain - Cerebellum: p = 2.86E-5 |
Estimated Glomerular Filtration Rate | Chronic Kidney Disease | Expanded Trait Collection (ETC) | Pattaro | 2016 | 12385 | 104780 | 5 | Liver: p = 0.00532 Whole Blood: p = 0.00637 Esophagus - Muscularis: p = 0.05 |
Glycemic Traits | Fasting Glucose | Expanded Trait Collection (ETC) | Dupuis | 2010 | 0 | 46186 | 5 | Liver: p = 6.94E-4 Pancreas: p = 0.0068 Artery - Coronary: p = 0.01 |
Glycemic Traits | Fasting Insulin | Expanded Trait Collection (ETC) | Dupuis | 2010 | 0 | 38238 | 3 | Whole Blood: p = 0.03 Adipose - Subcutaneous: p = 0.04 Adipose - Visceral (Omentum): p = 0.04 |
Inflammatory Bowel Disease European | Crohn's disease | Expanded Trait Collection (ETC) | Liu | 2015 | 5956 | 14927 | 5 | Whole Blood: p = 3.08E-10 Spleen: p = 5.27E-7 Lung: p = 6.59E-7 |
Inflammatory Bowel Disease European | Inflammatory Bowel Disease | Expanded Trait Collection (ETC) | Liu | 2015 | 12882 | 21770 | 4 | Whole Blood: p = 1.16E-9 Spleen: p = 7.81E-9 Lung: p = 6.17E-6 |
Inflammatory Bowel Disease European | Ulcerative Colitis | Expanded Trait Collection (ETC) | Liu | 2015 | 6968 | 20464 | 5 | Spleen: p = 4.29E-7 Whole Blood: p = 2.4E-6 Lung: p = 3.66E-5 |
Leptin | Leptin Not Adjusted For BMI | Expanded Trait Collection (ETC) | Kilpelainen | 2016 | 0 | 32161 | 3 | Brain - Cerebellum: p = 0.0094 Brain - Spinal cord (cervical c-1): p = 0.0094 Breast - Mammary Tissue: p = 0.02 |
Reproductive Behavior | Age First Birth Pooled | Expanded Trait Collection (ETC) | Barban | 2016 | 0 | 238064 | 5 | Brain - Anterior cingulate cortex (BA24): p = 1.32E-4 Brain - Amygdala: p = 4.54E-4 Brain - Frontal Cortex (BA9): p = 4.54E-4 |
Smoking | Cigarettes Per Day | Expanded Trait Collection (ETC) | Furberg | 2010 | 0 | 38181 | 3 | Esophagus - Gastroesophageal Junction: p = 0.01 Liver: p = 0.02 Esophagus - Muscularis: p = 0.03 |
BIP | Bipolar disorder | Expanded Trait Collection (ETC) | Stahl | 2018 | 20352 | 31358 | 4 | Brain - Frontal Cortex (BA9): p = 2.06E-4 Brain - Cortex: p = 5.7E-4 Brain - Cerebellum: p = 9.24E-4 |
SCZ | Schizophrenia | Expanded Trait Collection (ETC) | Ripke | 2014 | 32405 | 0 | 3 | Brain - Cortex: p = 4.98E-8 Brain - Frontal Cortex (BA9): p = 9.88E-8 Brain - Cerebellum: p = 3.75E-7 |
T1D | Type 1 Diabetes | Expanded Trait Collection (ETC) | Bradfield | 2011 | 9934 | 16956 | 5 | Spleen: p = 4.28E-13 Small Intestine - Terminal Ileum: p = 2.12E-8 Lung: p = 1.65E-5 |
PAN | Pancreatic Cancer | Expanded Trait Collection (ETC) | Amundadottir | 2009 | 1771 | 1805 | 3 | Small Intestine - Terminal Ileum: p = 6.62E-5 Whole Blood: p = 0.00124 Pancreas: p = 0.00201 |
COL | SSGAC_College | Expanded Trait Collection (ETC) | Rietveld | 2013 | 0 | 101069 | 4 | Brain - Putamen (basal ganglia): p = 0.00482 Brain - Cortex: p = 0.00616 Colon - Transverse: p = 0.00739 |
HGB | Hemoglobin Concentration | Expanded Trait Collection (ETC) | Astle | 2016 | 0 | 173480 | 3 | Spleen: p = 2.62E-6 Kidney - Cortex: p = 4.47E-6 Liver: p = 3.94E-4 |
MCH | Mean Corpuscular Hemoglobin | Expanded Trait Collection (ETC) | Astle | 2016 | 0 | 173480 | 3 | Whole Blood: p = 6.91E-8 Spleen: p = 8.56E-5 Liver: p = 0.00175 |
MCHC | Mean Corpuscular Hemoglobin Concentration | Expanded Trait Collection (ETC) | Astle | 2016 | 0 | 173480 | 4 | Whole Blood: p = 1.12E-6 Spleen: p = 0.00146 Colon - Transverse: p = 0.03 |
MCV | Mean Corpuscular Volume | Expanded Trait Collection (ETC) | Astle | 2016 | 0 | 173480 | 3 | Spleen: p = 3.45E-8 Whole Blood: p = 1.86E-7 Muscle - Skeletal: p = 0.00846 |
MPV | Mean Platelet Volume | Expanded Trait Collection (ETC) | Astle | 2016 | 0 | 173480 | 3 | Whole Blood: p = 4.94E-12 Artery - Aorta: p = 0.00269 Spleen: p = 0.00406 |
PLT | Platelet Count | Expanded Trait Collection (ETC) | Astle | 2016 | 0 | 173480 | 3 | Whole Blood: p = 5.38E-9 Spleen: p = 1.8E-5 Liver: p = 0.00337 |
RBC | Red Blood Cell Count | Expanded Trait Collection (ETC) | Astle | 2016 | 0 | 173480 | 3 | Kidney - Cortex: p = 1.04E-5 Spleen: p = 1.86E-4 Muscle - Skeletal: p = 4.44E-4 |
PBC | Primary Biliary Cirrhosis | Expanded Trait Collection (ETC) | Cordell | 2015 | 2764 | 10475 | 5 | Spleen: p = 2.9E-10 Small Intestine - Terminal Ileum: p = 1.68E-6 Lung: p = 4.43E-6 |
SLE | Systemic Lupus Erythematosus | Expanded Trait Collection (ETC) | Bentham | 2015 | 7219 | 15991 | 5 | Spleen: p = 8.23E-9 Whole Blood: p = 5.49E-7 Lung: p = 6.05E-4 |
RHR | CAD Resting Heart Rate | Expanded Trait Collection (ETC) | Eppinga | 2016 | 0 | 265046 | 4 | Artery - Coronary: p = 4.26E-6 Artery - Aorta: p = 6.85E-6 Artery - Tibial: p = 2.7E-5 |
T1D CA | Type1Diabetes (Childhood adiposity age < 17) | Expanded Trait Collection (ETC) | Censin | 2017 | 5913 | 8828 | 4 | Spleen: p = 8.98E-9 Whole Blood: p = 4.08E-6 Small Intestine - Terminal Ileum: p = 4.68E-5 |
EOC | Epithelial Ovarian Cancer | Expanded Trait Collection (ETC) | Phelan | 2017 | 25509 | 40941 | 5 | Colon - Sigmoid: p = 1.67E-6 Kidney - Cortex: p = 2.09E-6 Colon - Transverse: p = 1.22E-5 |
AUD | Alcohol Dependency | Expanded Trait Collection (ETC) | Walters | 2018 | 11569 | 34999 | 3 | Liver: p = 0.00153 Brain - Spinal cord (cervical c-1): p = 0.02 Uterus: p = 0.02 |
MS | Multiple Sclerosis | Expanded Trait Collection (ETC) | Patsopoulos | 2017 | 14802 | 26703 | 4 | Spleen: p = 2.02E-19 Whole Blood: p = 6.28E-17 Lung: p = 3.78E-4 |
SCZ | Schizophrenia | Expanded Trait Collection (ETC) | Pardinas | 2018 | 40675 | 64643 | 3 | Brain - Frontal Cortex (BA9): p = 1.61E-9 Brain - Cortex: p = 1.19E-8 Brain - Anterior cingulate cortex (BA24): p = 4.28E-8 |
CEL | Celiac Disease | Expanded Trait Collection (ETC) | Trynka | 2011 | 12041 | 12228 | 5 | Spleen: p = 1.91E-4 Whole Blood: p = 0.00183 Small Intestine - Terminal Ileum: p = 0.01 |
Glycine level | Glycine levels, both male and female | Expanded Trait Collection (ETC) | Jia | 2019 | 0 | 30118 | 2 | Small Intestine - Terminal Ileum: p = 0.02 Whole Blood: p = 0.08 Nerve - Tibial: p = 0.16 |
Handedness | Handedness, right-handed vs non-right-handed | Expanded Trait Collection (ETC) | Kovel | 2019 | 293857 | 37180 | 4 | Artery - Tibial: p = 0.00212 Muscle - Skeletal: p = 0.01 Artery - Aorta: p = 0.02 |
Ambidextrousness | Ambidextrousness | Expanded Trait Collection (ETC) | Kovel | 2019 | 5324 | 325713 | 3 | Brain - Nucleus accumbens (basal ganglia): p = 0.00816 Skin - Not Sun Exposed (Suprapubic): p = 0.00943 Skin - Sun Exposed (Lower leg): p = 0.00943 |
Handedness | Handedness, left-handed vs non-left-handed | Expanded Trait Collection (ETC) | Kovel | 2019 | 31856 | 299181 | 5 | Artery - Tibial: p = 9.48E-4 Brain - Cerebellar Hemisphere: p = 0.00222 Brain - Cerebellum: p = 0.00222 |
Parkinsons | Parkinsons disease, age of onset | Expanded Trait Collection (ETC) | Blauwendraat | 2019 | 0 | 17996 | 3 | Adrenal Gland: p = 0.01 Brain - Cerebellum: p = 0.02 Brain - Cerebellar Hemisphere: p = 0.03 |
Active | Time to most active 10 hours | Expanded Trait Collection (ETC) | Jones | 2019 | 0 | 85670 | 3 | Heart - Left Ventricle: p = 0.00141 Muscle - Skeletal: p = 0.0021 Heart - Atrial Appendage: p = 0.0031 |
Sleep | Sleep efficiency | Expanded Trait Collection (ETC) | Jones | 2019 | 0 | 84810 | 4 | Colon - Sigmoid: p = 5.85E-4 Brain - Frontal Cortex (BA9): p = 7.28E-4 Brain - Substantia nigra: p = 0.00161 |
Sleep | Sleep duration variability | Expanded Trait Collection (ETC) | Jones | 2019 | 0 | 84810 | 3 | Prostate: p = 0.00255 Brain - Amygdala: p = 0.00299 Brain - Hypothalamus: p = 0.00453 |
Sleep | Sleep duration | Expanded Trait Collection (ETC) | Jones | 2019 | 0 | 85449 | 5 | Brain - Frontal Cortex (BA9): p = 2.5E-4 Brain - Anterior cingulate cortex (BA24): p = 3.7E-4 Pituitary: p = 5.4E-4 |
Sleep | Sleep time to midpoint | Expanded Trait Collection (ETC) | Jones | 2019 | 0 | 84810 | 3 | Heart - Left Ventricle: p = 0.00128 Brain - Amygdala: p = 0.00139 Brain - Substantia nigra: p = 0.00277 |
Sleep | Sleep time to least active 5 hours | Expanded Trait Collection (ETC) | Jones | 2019 | 0 | 85205 | 3 | Brain - Frontal Cortex (BA9): p = 9.8E-4 Brain - Hippocampus: p = 0.00214 Brain - Anterior cingulate cortex (BA24): p = 0.00311 |
Sleep | Diurnal inactivity | Expanded Trait Collection (ETC) | Jones | 2019 | 0 | 84757 | 4 | Brain - Amygdala: p = 1.41E-6 Brain - Anterior cingulate cortex (BA24): p = 3.09E-5 Brain - Frontal Cortex (BA9): p = 4.97E-5 |
Sleep | Sleep number of episodes | Expanded Trait Collection (ETC) | Jones | 2019 | 0 | 84810 | 4 | Brain - Frontal Cortex (BA9): p = 7.78E-5 Brain - Amygdala: p = 3.41E-4 Brain - Anterior cingulate cortex (BA24): p = 3.41E-4 |
Facial attractiveness | Facial attractiveness, male raters | Expanded Trait Collection (ETC) | Hu | 2019 | 0 | 3928 | 2 | Heart - Atrial Appendage: p = 0.02 Uterus: p = 0.02 Nerve - Tibial: p = 0.02 |
Facial attractiveness | Facial attractiveness, female raters | Expanded Trait Collection (ETC) | Hu | 2019 | 0 | 3928 | 3 | Artery - Aorta: p = 5.69E-4 Artery - Coronary: p = 0.00558 Artery - Tibial: p = 0.00558 |
Facial attractiveness | Facial attractiveness of males, male raters | Expanded Trait Collection (ETC) | Hu | 2019 | 0 | 1792 | 3 | Lung: p = 0.02 Uterus: p = 0.03 Thyroid: p = 0.05 |
Facial attractiveness | Facial attractiveness of females, female raters | Expanded Trait Collection (ETC) | Hu | 2019 | 0 | 2062 | 3 | Stomach: p = 0.00414 Pancreas: p = 0.02 Heart - Atrial Appendage: p = 0.05 |
Facial attractiveness | Facial attractiveness of males, female raters | Expanded Trait Collection (ETC) | Hu | 2019 | 0 | 1792 | 3 | Pancreas: p = 0.00368 Colon - Transverse: p = 0.03 Esophagus - Mucosa: p = 0.05 |
Facial attractiveness | Facial attractiveness of females, male raters | Expanded Trait Collection (ETC) | Hu | 2019 | 0 | 2062 | 2 | Prostate: p = 0.00824 Skin - Sun Exposed (Lower leg): p = 0.01 Stomach: p = 0.02 |
Asthma | Asthma, adult-onset | Expanded Trait Collection (ETC) | Ferreira | 2019 | 26582 | 300671 | 4 | Whole Blood: p = 2.61E-7 Lung: p = 1.74E-5 Spleen: p = 9.83E-4 |
Asthma | Asthma, childhood-onset | Expanded Trait Collection (ETC) | Ferreira | 2019 | 13962 | 300671 | 4 | Whole Blood: p = 1.4E-8 Spleen: p = 7.0E-5 Esophagus - Mucosa: p = 2.48E-4 |
Neuroticism | General factor of neuroticism | Expanded Trait Collection (ETC) | Hill | 2019 | 0 | 270059 | 4 | Brain - Nucleus accumbens (basal ganglia): p = 1.13E-6 Brain - Caudate (basal ganglia): p = 8.17E-6 Brain - Cortex: p = 4.13E-5 |
Neuroticism | Worry-vulnerability-special-factor-of-neuroticism | Expanded Trait Collection (ETC) | Hill | 2019 | 0 | 270059 | 4 | Brain - Frontal Cortex (BA9): p = 4.27E-5 Brain - Cerebellar Hemisphere: p = 7.4E-5 Brain - Cortex: p = 7.4E-5 |
Neuroticism | Anxiety-tension-special-factor-of-neuroticism | Expanded Trait Collection (ETC) | Hill | 2019 | 0 | 270059 | 4 | Brain - Frontal Cortex (BA9): p = 4.27E-5 Brain - Cerebellar Hemisphere: p = 7.4E-5 Brain - Cortex: p = 7.4E-5 |
Na/K ratio | Urinary sodium to potassium ratio | Expanded Trait Collection (ETC) | Zanetti | 2019 | 0 | 108942 | 4 | Adrenal Gland: p = 3.09E-4 Pancreas: p = 0.00201 Uterus: p = 0.00347 |
K/C ratio | Urinary potassium to creatinine ratio | Expanded Trait Collection (ETC) | Zanetti | 2019 | 0 | 218435 | 4 | Muscle - Skeletal: p = 0.0033 Pancreas: p = 0.00577 Spleen: p = 0.00897 |
Sleep | Sleep duration, short sleep | Expanded Trait Collection (ETC) | Dashti | 2019 | 106192 | 305742 | 4 | Brain - Frontal Cortex (BA9): p = 3.81E-7 Brain - Caudate (basal ganglia): p = 2.46E-6 Brain - Cortex: p = 4.46E-6 |
Sleep | Sleep duration, long sleep | Expanded Trait Collection (ETC) | Dashti | 2019 | 34184 | 305742 | 5 | Adrenal Gland: p = 7.52E-4 Brain - Cerebellar Hemisphere: p = 0.00103 Brain - Frontal Cortex (BA9): p = 0.00465 |
Sleep | Sleep duration | Expanded Trait Collection (ETC) | Dashti | 2019 | 0 | 446118 | 4 | Brain - Putamen (basal ganglia): p = 6.08E-11 Brain - Cortex: p = 2.32E-10 Brain - Frontal Cortex (BA9): p = 4.48E-10 |
Glycine level | Glycine level | Expanded Trait Collection (ETC) | Wittemans | 2019 | 0 | 80003 | 5 | Liver: p = 1.45E-5 Whole Blood: p = 0.00434 Esophagus - Gastroesophageal Junction: p = 0.02 |
CTS | Carpal tunnel syndrome | Expanded Trait Collection (ETC) | Wiberg | 2019 | 12312 | 389344 | 4 | Artery - Aorta: p = 6.24E-5 Whole Blood: p = 6.58E-4 Heart - Atrial Appendage: p = 0.00146 |
MI/CF | Meconium ileus in cystic fibrosis | Expanded Trait Collection (ETC) | Gong | 2019 | 1115 | 5655 | 3 | Kidney - Cortex: p = 0.00385 Liver: p = 0.01 Muscle - Skeletal: p = 0.03 |
Insomnia | Insomnia symptoms, never-rarely vs sometimes usually | Expanded Trait Collection (ETC) | Lane | 2019 | 345022 | 108357 | 4 | Brain - Amygdala: p = 1.18E-4 Brain - Cerebellar Hemisphere: p = 1.84E-4 Brain - Substantia nigra: p = 2.84E-4 |
FEV1/FVC | Lung-function-FEV1-FVC | Expanded Trait Collection (ETC) | Shrine | 2019 | 0 | 321047 | 3 | Artery - Aorta: p = 3.39E-12 Colon - Sigmoid: p = 3.39E-12 Esophagus - Gastroesophageal Junction: p = 3.39E-12 |
Chronotype | Chronotype | Expanded Trait Collection (ETC) | Jones | 2019 | 0 | 449734 | 3 | Brain - Hippocampus: p = 6.57E-8 Brain - Frontal Cortex (BA9): p = 1.22E-7 Brain - Putamen (basal ganglia): p = 2.23E-7 |
Morning person | Morning person | Expanded Trait Collection (ETC) | Jones | 2019 | 252287 | 150908 | 3 | Brain - Frontal Cortex (BA9): p = 4.43E-6 Brain - Cerebellar Hemisphere: p = 4.29E-5 Brain - Cortex: p = 4.29E-5 |
BMI | Normal body mass index vs thin control, adult vs thin adult | Expanded Trait Collection (ETC) | McKay | 2019 | 6460 | 1471 | 3 | Ovary: p = 0.02 Brain - Cerebellar Hemisphere: p = 0.04 Brain - Cerebellum: p = 0.04 |
Obesity | Obesity, extreme obese children vs control adult | Expanded Trait Collection (ETC) | McKay | 2019 | 1456 | 6460 | 3 | Brain - Cerebellar Hemisphere: p = 0.00266 Brain - Anterior cingulate cortex (BA24): p = 0.00438 Brain - Cortex: p = 0.00438 |
Obesity | Obese children vs thin adults | Expanded Trait Collection (ETC) | McKay | 2019 | 1471 | 1456 | 4 | Stomach: p = 0.02 Small Intestine - Terminal Ileum: p = 0.02 Skin - Sun Exposed (Lower leg): p = 0.02 |
Vitiligo | Vitiligo late onset | Expanded Trait Collection (ETC) | Jin | 2019 | 1467 | 19156 | 5 | Spleen: p = 1.84E-7 Small Intestine - Terminal Ileum: p = 1.03E-6 Whole Blood: p = 6.76E-5 |
Vitiligo | Vitiligo early onset | Expanded Trait Collection (ETC) | Jin | 2019 | 704 | 9031 | 5 | Spleen: p = 7.66E-6 Lung: p = 4.33E-5 Whole Blood: p = 2.82E-4 |
Body fat distribution | Body fat distribution, leg fat ratio, female | Expanded Trait Collection (ETC) | Andersen | 2019 | 0 | 116138 | 3 | Artery - Tibial: p = 3.48E-5 Artery - Coronary: p = 8.58E-5 Whole Blood: p = 2.96E-4 |
Body fat distribution | Body fat distribution, leg fat ratio, male | Expanded Trait Collection (ETC) | Andersen | 2019 | 0 | 116138 | 4 | Colon - Sigmoid: p = 1.6E-6 Esophagus - Gastroesophageal Junction: p = 1.49E-5 Esophagus - Muscularis: p = 2.53E-5 |
Body fat distribution | Body fat distribution-trunk-fat-ratio-female | Expanded Trait Collection (ETC) | Andersen | 2019 | 0 | 116138 | 3 | Artery - Tibial: p = 4.91E-7 Uterus: p = 4.91E-7 Artery - Coronary: p = 8.3E-7 |
Body fat distribution | Body fat distribution-trunk-fat-ratio-male | Expanded Trait Collection (ETC) | Andersen | 2019 | 0 | 116138 | 4 | Colon - Sigmoid: p = 4.84E-5 Esophagus - Gastroesophageal Junction: p = 2.19E-4 Esophagus - Muscularis: p = 3.52E-4 |
Body fat distribution | Body fat distribution-arm-fat-ratio-female | Expanded Trait Collection (ETC) | Andersen | 2019 | 0 | 116138 | 3 | Uterus: p = 6.51E-6 Brain - Cerebellum: p = 5.65E-5 Esophagus - Gastroesophageal Junction: p = 1.43E-4 |
Body fat distribution | Body fat distribution-arm-fat-ratio-male | Expanded Trait Collection (ETC) | Andersen | 2019 | 0 | 116138 | 4 | Adipose - Subcutaneous: p = 3.28E-4 Esophagus - Gastroesophageal Junction: p = 3.28E-4 Artery - Tibial: p = 0.00108 |
Osteoarthritis | Osteoarthritis | Expanded Trait Collection (ETC) | Tachmazidou | 2019 | 77052 | 378169 | 4 | Whole Blood: p = 0.00368 Brain - Cerebellum: p = 0.01 Brain - Nucleus accumbens (basal ganglia): p = 0.02 |
Osteoarthritis | Osteoarthritis of the hip or knee | Expanded Trait Collection (ETC) | Tachmazidou | 2019 | 39427 | 378169 | 4 | Artery - Coronary: p = 0.00241 Artery - Aorta: p = 0.00361 Heart - Atrial Appendage: p = 0.01 |
Osteoarthritis | Osteoarthritis hip | Expanded Trait Collection (ETC) | Tachmazidou | 2019 | 15704 | 378169 | 5 | Artery - Coronary: p = 1.44E-5 Colon - Sigmoid: p = 8.75E-5 Esophagus - Gastroesophageal Junction: p = 1.34E-4 |
Osteoarthritis | Knee osteoarthritis | Expanded Trait Collection (ETC) | Tachmazidou | 2019 | 24955 | 376169 | 4 | Esophagus - Gastroesophageal Junction: p = 3.52E-4 Spleen: p = 0.00201 Artery - Coronary: p = 0.00226 |
Brain volume | White matter hyperintensity volume | Expanded Trait Collection (ETC) | Traylor | 2019 | 0 | 8429 | 4 | Skin - Sun Exposed (Lower leg): p = 3.86E-4 Artery - Aorta: p = 0.00158 Liver: p = 0.00181 |
Smoking | Smoking initiation ever regular vs never-regular | Expanded Trait Collection (ETC) | Liua | 2019 | 0 | 1232091 | 4 | Brain - Anterior cingulate cortex (BA24): p = 1.48E-10 Brain - Amygdala: p = 5.32E-10 Brain - Frontal Cortex (BA9): p = 5.32E-10 |
Alcohol consumption | Alcohol consumption, drinks-per-week | Expanded Trait Collection (ETC) | Liua | 2019 | 0 | 941280 | 4 | Brain - Cerebellar Hemisphere: p = 7.93E-7 Brain - Cerebellum: p = 7.93E-7 Brain - Frontal Cortex (BA9): p = 1.28E-5 |
Smoking | Smoking cessation | Expanded Trait Collection (ETC) | Liua | 2019 | 0 | 547219 | 5 | Brain - Cortex: p = 9.6E-6 Esophagus - Muscularis: p = 1.59E-5 Brain - Anterior cingulate cortex (BA24): p = 1.06E-4 |
Smoking | Smoking behaviour, cigarettes smoked per day | Expanded Trait Collection (ETC) | Liua | 2019 | 0 | 377334 | 4 | Liver: p = 9.19E-5 Uterus: p = 0.00449 Brain - Anterior cingulate cortex (BA24): p = 0.00472 |
Smoking | Age of smoking initiation | Expanded Trait Collection (ETC) | Liua | 2019 | 0 | 341427 | 4 | Colon - Transverse: p = 4.95E-4 Kidney - Cortex: p = 0.00108 Small Intestine - Terminal Ileum: p = 0.0019 |
Depression | Depressive-symptoms | Expanded Trait Collection (ETC) | Baselmans | 2019 | 0 | 1067913 | 5 | Adrenal Gland: p = 9.49E-6 Brain - Frontal Cortex (BA9): p = 2.76E-4 Brain - Cerebellar Hemisphere: p = 6.5E-4 |
Neuroticism | Neuroticism | Expanded Trait Collection (ETC) | Baselmans | 2019 | 0 | 523783 | 5 | Brain - Frontal Cortex (BA9): p = 1.31E-4 Brain - Nucleus accumbens (basal ganglia): p = 2.09E-4 Brain - Putamen (basal ganglia): p = 3.17E-4 |
Positive affect | Positive affect | Expanded Trait Collection (ETC) | Baselmans | 2019 | 0 | 410603 | 5 | Uterus: p = 0.00716 Brain - Frontal Cortex (BA9): p = 0.05 Artery - Tibial: p = 0.06 |
Life satisfaction | Life satisfaction | Expanded Trait Collection (ETC) | Baselmans | 2019 | 0 | 80852 | 5 | Uterus: p = 0.00443 Testis: p = 0.03 Skin - Sun Exposed (Lower leg): p = 0.08 |
Body fat | Body fat percentage | Expanded Trait Collection (ETC) | Hubel | 2018 | 70700 | 85261 | 4 | Brain - Cerebellar Hemisphere: p = 2.1E-7 Brain - Cerebellum: p = 2.1E-7 Brain - Hippocampus: p = 9.99E-7 |
Postburn scar height | Postburn scar height | Expanded Trait Collection (ETC) | Wallace | 2018 | 0 | 665 | 2 | Pituitary: p = 0.00574 Lung: p = 0.03 Whole Blood: p = 0.04 |
Postburn scar pliability | Postburn scar pliability | Expanded Trait Collection (ETC) | Wallace | 2018 | 0 | 665 | 2 | Brain - Amygdala: p = 0.02 Pituitary: p = 0.02 Brain - Cerebellar Hemisphere: p = 0.05 |
Erectile dysfunction | Erectile dysfunction | Expanded Trait Collection (ETC) | Bovijn | 2018 | 6175 | 217630 | 3 | Esophagus - Muscularis: p = 3.3E-4 Esophagus - Gastroesophageal Junction: p = 0.00243 Brain - Hypothalamus: p = 0.0029 |
Male baldness | Male pattern baldness | Expanded Trait Collection (ETC) | Yap | 2018 | 0 | 205327 | 3 | Vagina: p = 1.59E-13 Prostate: p = 3.29E-7 Esophagus - Mucosa: p = 1.16E-6 |
Psoriatic arthritis | Psoriatic arthritis | Expanded Trait Collection (ETC) | Aterido | 2018 | 744 | 1454 | 3 | Spleen: p = 0.00219 Lung: p = 0.01 Muscle - Skeletal: p = 0.01 |
Asthma | Asthma, moderate or severe | Expanded Trait Collection (ETC) | Shrine | 2018 | 5414 | 21471 | 5 | Lung: p = 1.34E-5 Whole Blood: p = 1.86E-5 Spleen: p = 8.31E-4 |
Sleep | Sleep duration | Expanded Trait Collection (ETC) | Doherty | 2018 | 0 | 91105 | 5 | Brain - Frontal Cortex (BA9): p = 5.5E-4 Brain - Cortex: p = 7.28E-4 Pituitary: p = 0.00149 |
Physical activity | Physical activity, overall physical activity time | Expanded Trait Collection (ETC) | Doherty | 2018 | 0 | 91105 | 5 | Brain - Cerebellar Hemisphere: p = 1.86E-7 Brain - Cerebellum: p = 7.93E-7 Brain - Caudate (basal ganglia): p = 6.52E-6 |
Sedentary behaviour duration | Sedentary behaviour duration | Expanded Trait Collection (ETC) | Doherty | 2018 | 0 | 91105 | 4 | Brain - Hippocampus: p = 2.76E-7 Brain - Anterior cingulate cortex (BA24): p = 1.48E-6 Brain - Cortex: p = 5.74E-6 |
Physical activity | Physical activity, walking duration | Expanded Trait Collection (ETC) | Doherty | 2018 | 0 | 91105 | 3 | Brain - Anterior cingulate cortex (BA24): p = 2.7E-6 Skin - Not Sun Exposed (Suprapubic): p = 3.91E-5 Skin - Sun Exposed (Lower leg): p = 8.63E-5 |
Physical activity | Physical activity, moderate intensity activity duration | Expanded Trait Collection (ETC) | Doherty | 2018 | 0 | 91105 | 4 | Brain - Frontal Cortex (BA9): p = 2.22E-6 Brain - Anterior cingulate cortex (BA24): p = 3.74E-5 Brain - Caudate (basal ganglia): p = 3.74E-5 |
Nonischemic cardiomyopathy | Nonischemic cardiomyopathy | Expanded Trait Collection (ETC) | Aragam | 2018 | 1816 | 388326 | 3 | Esophagus - Muscularis: p = 0.00725 Brain - Spinal cord (cervical c-1): p = 0.01 Brain - Substantia nigra: p = 0.01 |
Heart failure | Heart failure | Expanded Trait Collection (ETC) | Aragam | 2018 | 6504 | 387652 | 3 | Uterus: p = 6.22E-4 Artery - Coronary: p = 0.00247 Esophagus - Muscularis: p = 0.00678 |
Hippocampal volume | Hippocampal tail volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Nerve - Tibial: p = 1.06E-4 Uterus: p = 0.0016 Artery - Aorta: p = 0.00624 |
Fimbria volume | Fimbria volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Breast - Mammary Tissue: p = 7.18E-4 Adipose - Subcutaneous: p = 0.00209 Adipose - Visceral (Omentum): p = 0.00209 |
Parasubiculum volume | Parasubiculum volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 4 | Heart - Left Ventricle: p = 0.00222 Adipose - Subcutaneous: p = 0.00594 Colon - Transverse: p = 0.02 |
Hippocampal volume | Hippocampal fissure volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 2 | Artery - Tibial: p = 0.00451 Artery - Aorta: p = 0.01 Brain - Cerebellum: p = 0.03 |
Brain volume | Dentate gyrus molecular layer volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Esophagus - Muscularis: p = 0.00312 Adipose - Subcutaneous: p = 0.01 Colon - Sigmoid: p = 0.01 |
Brain volume | Dentate gyrus granule cell layer volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Adipose - Subcutaneous: p = 0.02 Esophagus - Gastroesophageal Junction: p = 0.03 Adipose - Visceral (Omentum): p = 0.06 |
Hippocampal volume | Hippocampal subfield CA4 volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Breast - Mammary Tissue: p = 0.00115 Adipose - Subcutaneous: p = 0.03 Adipose - Visceral (Omentum): p = 0.03 |
Hippocampal volume | Total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 4 | Artery - Tibial: p = 0.01 Muscle - Skeletal: p = 0.03 Prostate: p = 0.06 |
Hippocampal volume | Hippocampal subfield CA1 volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Adipose - Visceral (Omentum): p = 4.04E-4 Adipose - Subcutaneous: p = 0.00117 Pancreas: p = 0.01 |
Subiculum volume | Subiculum volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Skin - Not Sun Exposed (Suprapubic): p = 0.00707 Skin - Sun Exposed (Lower leg): p = 0.00707 Esophagus - Gastroesophageal Junction: p = 0.00732 |
Presubiculum volume | Presubiculum volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Skin - Not Sun Exposed (Suprapubic): p = 0.02 Skin - Sun Exposed (Lower leg): p = 0.02 Brain - Spinal cord (cervical c-1): p = 0.05 |
HATA volume | HATA volume corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Prostate: p = 0.03 Nerve - Tibial: p = 0.04 Breast - Mammary Tissue: p = 0.04 |
Fimbria volume | Fimbria volume corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 2 | Breast - Mammary Tissue: p = 0.01 Skin - Sun Exposed (Lower leg): p = 0.04 Esophagus - Mucosa: p = 0.06 |
Hippocampal volume | Hippocampal tail volume, corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Artery - Coronary: p = 0.00929 Artery - Tibial: p = 0.01 Esophagus - Muscularis: p = 0.02 |
Hippocampal volume | Hippocampal fissure volume, corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Nerve - Tibial: p = 0.00308 Artery - Aorta: p = 0.02 Artery - Coronary: p = 0.02 |
Brain volume | Dentate gyrus molecular layer volume, corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Artery - Coronary: p = 0.03 Artery - Tibial: p = 0.03 Muscle - Skeletal: p = 0.04 |
Brain volume | Dentate gyrus granule cell layer volume corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Brain - Anterior cingulate cortex (BA24): p = 0.04 Brain - Cortex: p = 0.04 Brain - Hippocampus: p = 0.04 |
Hippocampal volume | Hippocampal subfield CA4 volume, corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Adrenal Gland: p = 0.04 Minor Salivary Gland: p = 0.05 Artery - Tibial: p = 0.05 |
Hippocampal volume | Hippocampal subfield CA3 volume, corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Muscle - Skeletal: p = 0.00262 Adrenal Gland: p = 0.00534 Adipose - Visceral (Omentum): p = 0.05 |
Hippocampal volume | Hippocampal subfield CA1 volume, corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 4 | Artery - Aorta: p = 0.02 Artery - Coronary: p = 0.02 Artery - Tibial: p = 0.02 |
Subiculum volume | Subiculum volume, corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 4 | Nerve - Tibial: p = 0.00231 Artery - Tibial: p = 0.00369 Artery - Coronary: p = 0.00578 |
Parasubiculum volume | Presubiculum volume, corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Uterus: p = 0.00145 Nerve - Tibial: p = 0.00429 Skin - Sun Exposed (Lower leg): p = 0.00672 |
HATA volume | Hippocampal amygdala transition area volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Prostate: p = 0.00414 Pituitary: p = 0.00432 Breast - Mammary Tissue: p = 0.01 |
Hippocampal volume | Hippocampal subfield CA3 volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 4 | Muscle - Skeletal: p = 0.04 Adipose - Visceral (Omentum): p = 0.05 Artery - Aorta: p = 0.05 |
Parasubiculum volume | Parasubiculum volume, corrected for total hippocampal volume | Expanded Trait Collection (ETC) | Meer | 2018 | 0 | 21297 | 3 | Colon - Transverse: p = 0.00153 Liver: p = 0.00534 Esophagus - Gastroesophageal Junction: p = 0.01 |
IHPS | Infantile hypertrophic pyloric stenosis | Expanded Trait Collection (ETC) | Fadista | 2018 | 0 | 4438 | 4 | Esophagus - Muscularis: p = 3.16E-4 Colon - Sigmoid: p = 5.08E-4 Esophagus - Gastroesophageal Junction: p = 5.08E-4 |
ACR | Urinary albumin to creatinine ratio | Expanded Trait Collection (ETC) | Zanetti | 2019 | 0 | 218759 | 4 | Nerve - Tibial: p = 0.0012 Uterus: p = 0.00193 Liver: p = 0.00708 |
Na/C | Urinary sodium to creatinine ratio | Expanded Trait Collection (ETC) | Zanetti | 2019 | 0 | 218450 | 4 | Brain - Hypothalamus: p = 1.26E-4 Brain - Spinal cord (cervical c-1): p = 3.52E-4 Brain - Anterior cingulate cortex (BA24): p = 9.2E-4 |
AUD | Alcohol-Use-Disorder | Expanded Trait Collection (ETC) | Kranzler | 2019 | 34658 | 167346 | 5 | Brain - Cerebellum: p = 7.11E-4 Muscle - Skeletal: p = 0.00105 Brain - Frontal Cortex (BA9): p = 0.0022 |
AUDIT-C | Alcohol-Use-Disorder-Identification-Test-Consumption | Expanded Trait Collection (ETC) | Kranzler | 2019 | 0 | 200680 | 4 | Brain - Cerebellar Hemisphere: p = 1.61E-4 Brain - Cerebellum: p = 2.85E-4 Liver: p = 0.00119 |