deTS Results for Hippocampal subfield CA4 volume

Traits Information:

Trait ID:

5341

Hippocampal volume
Hippocampal subfield CA4 volume
Expanded Trait Collection (ETC)
Meer , 2018
30279459
# cases = 0 | # controls = 21297
# SNPs = 6003775 | # genes = 21864
1.058
p (gene) < 0.05:  # TAGs = 1142
p (gene) < 0.01:  # TAGs = 272
p (gene) < 0.001:  # TAGs = 29
p (gene) < 1.0E-4:  # TAGs = 3
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.2120.4490.4490.3830.9280.07350.3210.2120.4490.7140.5170.4490.3830.2640.3830.3210.7140.2640.4490.3830.9280.09870.5850.05360.8640.90.5170.8640.9990.3830.9280.4490.7140.2640.950.9990.1680.7710.6510.5850.6480.8640.09870.5850.2640.5170.8210.0320.0320.6650.5280.9450.06030.2720.3920.1760.3920.5280.5280.1760.3920.5280.5280.1760.5280.0320.3920.5280.6650.9790.6650.6650.3920.3920.9450.9450.3920.8830.6650.9450.3920.6650.9790.1760.6650.5280.7880.5260.2720.2720.06030.2720.8830.7880.05010.05010.5820.5821.00.5820.5820.5821.01.01.01.00.5820.5820.5820.5820.5820.5820.001151.00.2081.01.01.01.00.5820.5820.5821.01.01.00.5820.5820.2081.01.01.00.5820.05010.05011.00.05010.2081.00.5820.5820.582Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.1330.07290.7890.1330.7320.7890.2650.3920.7290.5340.4640.003170.4570.990.03820.7890.2180.670.9940.4640.9390.9890.8380.7290.6670.670.5340.9130.3310.670.3890.7890.9940.8770.3920.8770.8380.9130.9940.10.2180.9130.8790.1330.0250.02470.8640.150.9350.760.9340.3520.4870.150.0250.04850.2360.9350.4890.9750.760.9350.9750.760.630.6260.630.8630.7580.630.8640.8640.8640.760.4850.630.9350.7580.3521.00.9750.9930.760.150.150.9750.8640.08840.04970.04950.5811.00.5810.5810.580.04950.580.2070.2070.5810.580.5811.01.01.01.00.5810.5810.5810.2060.5811.01.01.00.5811.00.5811.01.00.2071.01.01.01.00.2071.00.5810.2070.2071.00.5810.581Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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