deTS Results for Morning/evening person (chronotype)

Traits Information:

Trait ID:

1232

1180
Morning/evening person (chronotype)
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=1180
# cases = 0 | # controls = 322488
# SNPs = 13585565 | # genes = 21891
1.347
p (gene) < 0.05:  # TAGs = 5914
p (gene) < 0.01:  # TAGs = 3132
p (gene) < 0.001:  # TAGs = 1477
p (gene) < 1.0E-4:  # TAGs = 689
p (gene) < 1.0E-5:  # TAGs = 352

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.001 p < 1.0E-4 p < 1.0E-5 0.7030.7030.8020.4670.07750.001450.002262.12E-40.001450.007740.007740.001455.73E-40.002261.26E-42.12E-40.005227.4E-50.4670.2020.3490.07750.6470.1010.7030.4070.4070.3490.8020.5280.7030.8020.1290.1630.7030.7550.007740.5880.8020.8430.8410.8790.9990.6470.5280.7550.7550.4740.8590.980.7990.2380.009860.009860.009860.01630.04090.009860.02620.009860.005780.001820.02620.04090.005780.5620.3090.3880.02620.1780.1780.2380.3090.5620.940.4740.4740.4740.3880.6480.04090.7280.7280.005780.5620.5620.5620.9040.7990.9980.8590.3090.3880.8590.3180.8710.9880.9690.7850.01580.02980.05340.007940.09070.05340.09070.05340.007940.05340.09070.02987.55E-40.4330.6770.6770.09070.5560.3180.4330.09070.2220.9690.6770.3180.4330.7850.6770.05340.7850.7850.01580.9880.2220.09070.9310.8710.9990.9690.4330.5560.785Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.001 p < 1.0E-4 p < 1.0E-5 0.7070.9680.9690.006770.04040.09630.01382.6E-60.03951.74E-50.9860.9370.2840.590.05490.760.09630.5280.590.2920.1580.880.4660.01420.03950.650.7070.590.1240.760.520.3460.2920.2880.9120.8460.9550.9130.9370.9990.5281.00.7070.9130.8750.9710.9190.06460.1870.005870.009682.45E-40.04195.45E-60.7490.670.7450.4940.06460.3230.1350.4060.8180.4060.5830.9960.4060.04190.2480.670.4060.670.670.670.4880.4940.7490.4030.8740.7470.8750.670.8750.9990.670.9990.5830.8180.4950.9830.9830.03760.1120.01010.009863.93E-40.0664.01E-40.6220.740.8360.9580.2650.6220.1770.6220.2650.1770.3730.9570.1120.03720.1110.9110.6220.9580.9580.740.4920.3730.9580.620.8380.7390.4950.3730.740.9830.741.00.6220.622Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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