deTS Results for Diagnoses - main ICD10: N28 Other disorders of kidney and ureter, not elsewhere classified

Traits Information:

Trait ID:

181

N28
Diagnoses - main ICD10: N28 Other disorders of kidney and ureter, not elsewhere classified
UK Biobank (UKBB)
Neale Lab, 2018
# cases = 452 | # controls = 360742
# SNPs = 8057442 | # genes = 21888
1.01
p (gene) < 0.05:  # TAGs = 1187
p (gene) < 0.01:  # TAGs = 271
p (gene) < 0.001:  # TAGs = 12
p (gene) < 1.0E-4:  # TAGs = 0
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS




Manhattan Plot of All Genes in the GWAS


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deTS Enrichment Analysis Using the GTEx Panel


p < 0.05 p < 0.01 0.04980.1590.5720.8120.7020.760.7020.4360.7020.5720.760.7020.7020.8940.5040.5720.1230.5040.5040.1590.1590.06860.370.1230.5720.5040.8120.06860.5040.04980.8940.8120.6390.5720.7020.760.06860.9240.5720.2520.2490.8120.9860.8120.2520.370.8570.6130.6130.7460.8550.3380.7460.8550.4720.4720.4720.8550.7460.8550.7460.4720.4720.7460.8550.8550.0440.140.08120.08120.140.7460.4720.4720.2250.3380.01060.9980.9290.3380.3380.2250.6130.08120.9720.7460.4720.470.9290.7460.9290.4720.6130.855Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel


p < 0.05 p < 0.01 0.3120.3720.7150.9810.8250.9040.6440.5790.9530.4430.2540.2030.03240.5130.2030.3120.5830.3760.2540.8680.7730.2480.2540.440.1190.2540.2540.9890.8250.8250.3060.3760.5130.3720.9530.7120.3760.970.970.8680.6510.3120.3120.0480.2880.1840.8240.9640.8240.8240.910.7020.7020.5610.110.4180.06010.7030.4180.2880.7030.7030.4180.110.5610.1090.2880.2870.03130.9110.8240.2880.4180.5610.5580.7030.7030.560.9980.7020.5610.9110.7030.7030.4180.110.110.824Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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