deTS Results for Belittlement by partner or ex-partner as an adult

Traits Information:

Trait ID:

1983

20521
Belittlement by partner or ex-partner as an adult
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20521
# cases = 0 | # controls = 117741
# SNPs = 13571675 | # genes = 21888
1.054
p (gene) < 0.05:  # TAGs = 1614
p (gene) < 0.01:  # TAGs = 423
p (gene) < 0.001:  # TAGs = 57
p (gene) < 1.0E-4:  # TAGs = 4
p (gene) < 1.0E-5: # TAGs = 2

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.8190.7760.8190.9670.7290.006020.002720.1017.42E-40.001790.002720.001790.02460.01250.03360.1280.1970.1280.2860.4480.5060.6770.9850.4480.9370.9940.9540.5060.1010.01770.9670.4480.8560.6220.4480.8190.03360.1010.990.9850.04430.4480.5640.1970.4480.5640.8880.9860.9860.8890.9950.9860.220.1510.3060.01150.03680.220.1510.7310.6280.3060.3060.5170.6280.7310.4070.4070.6280.9690.7310.820.820.6280.09860.06160.220.9380.7310.9860.7310.5170.5170.4070.220.8890.9380.02070.4070.9380.220.6280.3060.5171.01.00.8840.8840.6280.6280.6280.8840.05690.05690.3510.8840.8840.6280.8840.8841.00.8840.3510.8840.3511.01.01.01.00.8840.8840.1560.6280.1560.8840.8841.00.8840.05690.6280.6280.6280.3510.3510.004390.01731.00.6280.8840.8840.156Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.3160.6590.9990.003030.01420.9777.51E-40.001230.004410.05130.06810.3710.760.4870.9120.9770.9120.6060.8510.8510.7170.760.020.1120.05010.7170.4870.9120.7170.6630.420.8510.3160.06660.3130.9941.00.9850.9120.7670.3160.9940.3160.5470.7040.4820.9944.79E-40.1310.9990.001020.001040.130.1950.7980.9840.7950.5960.9980.7980.9840.2770.7980.8740.9630.4794.79E-40.08330.1940.9630.8740.9840.9840.7040.8710.9630.7040.2750.130.9270.9840.9840.2770.8740.03010.4840.7980.9280.6130.8770.8770.3350.8771.00.6110.8770.8770.6130.6131.00.6110.3351.01.01.00.3351.00.3350.8770.3330.8770.6120.05131.00.8771.01.00.8770.3330.1460.8770.3340.1450.8770.6130.8770.1460.3350.6130.003781.00.877Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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