deTS Results for Attendance/disability/mobility allowance: Blue badge

Traits Information:

Trait ID:

2061

6146_3
Attendance/disability/mobility allowance: Blue badge
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=6146
# cases = 12733 | # controls = 345864
# SNPs = 13586548 | # genes = 21889
1.097
p (gene) < 0.05:  # TAGs = 2162
p (gene) < 0.01:  # TAGs = 641
p (gene) < 0.001:  # TAGs = 128
p (gene) < 1.0E-4:  # TAGs = 35
p (gene) < 1.0E-5: # TAGs = 3

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 p < 1.0E-4 0.6330.6330.02640.07430.01060.007680.01060.005470.02640.03480.01465.56E-40.01460.05840.01060.01060.2450.09340.2070.01460.3790.01970.04540.01460.3790.1160.3310.6810.920.1720.480.04540.03480.01460.8980.480.5310.2070.01060.01060.4240.2070.2070.01060.09340.01060.8980.4360.2010.0680.1450.02790.2690.1450.1010.2010.4360.0680.0680.2690.8510.1450.1450.5280.8510.2010.04430.3480.04430.1450.04430.7080.1010.2010.8510.9020.620.1450.02790.1450.02790.940.3480.8510.4360.2010.1010.3450.7850.5280.04430.7080.5280.9820.9840.7770.01950.0490.0490.5820.5820.5820.3810.3810.7770.3810.3810.5820.5820.5820.3810.7770.9180.110.2180.0490.2180.0490.5820.0490.2180.5820.9180.5820.110.0490.3810.110.7770.2180.9840.7770.110.110.1090.7770.01950.2180.9180.3810.7770.6770.6770.09460.09460.09460.6770.6770.6770.3020.3020.6770.6770.6770.6770.6770.6770.09460.6771.00.09460.6770.09460.3020.02210.6770.003980.3020.09460.6770.3020.6770.6770.3020.09460.3021.01.00.6770.3020.3020.6761.00.09461.00.6770.6770.677Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 p < 1.0E-4 0.8090.7660.6790.8740.5260.2770.1570.08410.2720.0230.0170.06790.1570.4730.0170.03070.04060.08620.370.630.7690.7180.630.9550.06620.9230.8090.5780.1340.1630.8690.7260.7260.4160.5210.02990.03070.7260.5260.8090.04060.9950.5780.5260.2950.6550.6570.5650.9220.7420.6530.5620.8750.2220.01930.4710.3740.2220.07650.2220.050.07650.6570.5650.7420.8740.4710.9210.5620.9870.5650.2220.4710.07650.4650.9220.2950.3770.6550.07560.03160.1610.6570.5650.050.8160.2950.9220.9060.5480.01520.9060.3481.00.3460.1920.1920.9060.5490.9060.09210.09320.03990.1920.01520.3480.9060.5490.7530.7510.7530.9820.7520.7530.5490.3480.5490.3480.3460.5490.09320.3470.3470.03960.3480.3480.9820.1920.1920.5490.5490.7531.00.640.07470.640.641.01.00.640.640.640.641.00.002480.640.01560.2630.07470.2630.640.641.00.2621.01.00.2620.640.641.00.641.00.6390.641.00.640.640.640.640.641.00.640.640.2630.07470.263Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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