deTS Results for Mouth/teeth dental problems: None of the above

Traits Information:

Trait ID:

2076

6149_100
Mouth/teeth dental problems: None of the above
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=6149
# cases = 218346 | # controls = 141495
# SNPs = 13586547 | # genes = 21892
1.154
p (gene) < 0.05:  # TAGs = 3599
p (gene) < 0.01:  # TAGs = 1510
p (gene) < 0.001:  # TAGs = 447
p (gene) < 1.0E-4:  # TAGs = 206
p (gene) < 1.0E-5:  # TAGs = 116

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.01 p < 0.001 p < 1.0E-4 p < 1.0E-5 0.820.6660.7220.9730.7220.820.8930.7740.2520.04290.6660.860.8930.8930.7220.7740.860.9210.7740.1310.6060.1310.2520.2520.4190.3040.820.860.2520.6060.01550.6060.2520.2520.9730.9730.9820.4190.01550.007230.6631.03E-40.6660.820.7220.2524.9E-40.2420.2420.2420.8370.3320.6530.8370.5440.6530.6530.7530.9450.7530.9010.6530.6530.4340.8370.4340.1680.7530.07120.3320.1680.9450.6530.9010.8370.8370.7530.007460.7530.4340.07120.9010.9880.7530.7530.1680.1120.8350.003820.9011.00.1120.5441.64E-60.4670.630.4670.7790.7790.630.7790.7790.4670.4670.630.7790.7790.7790.7790.8920.630.8920.7790.3170.4670.1970.3170.4670.7790.8920.960.630.7790.632.34E-40.960.7790.630.960.960.630.8920.3170.1120.3166.03E-60.8920.990.4670.962.34E-40.5520.7550.5520.9070.7550.5520.5520.5520.1940.1940.3510.5520.5520.5520.5520.7550.1940.7550.5520.7550.9070.3510.9070.5520.7550.9070.9070.1940.7550.1944.63E-40.9820.9070.5520.9070.9070.9070.9070.7550.7550.551.21E-60.9070.9070.5520.9824.63E-4Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.01 p < 0.001 p < 1.0E-4 p < 1.0E-5 0.9860.6860.5680.3790.5680.9780.6830.1720.2150.630.9530.9780.4320.690.440.630.320.2660.9680.630.7450.3130.440.5640.2150.440.0110.3790.3790.690.6230.3790.630.4360.9520.1050.06120.9914.94E-60.7960.630.9780.9080.840.1340.280.05310.2820.930.930.9640.80.80.380.7090.9840.2780.8760.08650.6020.05310.6020.9980.8760.9940.1320.9640.7070.80.6020.01740.1990.7090.2820.08470.6020.930.7070.80.1980.380.8766.72E-100.930.9640.8020.4890.9840.7520.9520.4310.9520.7520.9520.8740.7510.430.2840.8760.9980.1690.7520.4310.5960.1710.5960.9880.8760.9520.4280.9520.9870.7510.9520.04740.8760.7520.8760.09270.5960.7520.5940.430.170.5960.9527.35E-110.8760.9520.9520.8760.9880.5180.8930.5180.8940.5180.9790.5150.3170.1690.5180.8940.9790.5151.00.7290.5180.3180.3180.9790.8940.8940.5150.8940.8930.3170.7290.07930.8940.8940.8940.1680.7290.7291.00.3170.9780.9790.9796.75E-120.9790.8940.7290.8940.894Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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