deTS Results for Non-cancer illness code, self-reported: cholecystitis

Traits Information:

Trait ID:

2281

20002_1163
Non-cancer illness code, self-reported: cholecystitis
UK Biobank (UKBB)
Neale Lab, 2018
# cases = 381 | # controls = 360760
# SNPs = 7689811 | # genes = 21888
0.998
p (gene) < 0.05:  # TAGs = 1137
p (gene) < 0.01:  # TAGs = 272
p (gene) < 0.001:  # TAGs = 21
p (gene) < 1.0E-4:  # TAGs = 3
p (gene) < 1.0E-5: # TAGs = 3

Manhattan Plot of All SNPs in the GWAS




Manhattan Plot of All Genes in the GWAS


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deTS Enrichment Analysis Using the GTEx Panel


p < 0.05 p < 0.01 p < 0.001 0.1850.7960.9980.9740.9990.8830.9150.8430.960.8830.8430.8430.8830.7960.7960.8830.6160.8830.2870.9150.5480.9740.1850.960.8430.480.6160.8430.06070.3470.3470.3470.480.3470.7420.3470.480.1450.04370.08270.5450.6160.480.4120.4120.1850.8830.5070.8730.9770.8730.9930.8730.7730.8730.940.7730.8730.940.940.940.8730.8730.9990.9930.5070.940.09650.940.2540.940.09650.09650.2540.5070.09650.6460.001130.05380.8730.6460.6460.6460.7730.2540.6460.6460.2530.006340.3710.3710.05380.3710.3710.1350.1350.4870.4871.01.01.01.01.01.01.01.01.01.01.01.01.01.00.4870.4871.00.4871.00.4871.01.00.4871.01.00.02440.1351.00.4870.4870.1350.4870.4871.00.4870.4870.4860.4871.01.00.02441.00.487Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel


p < 0.05 p < 0.01 p < 0.001 0.5690.8130.9870.6380.2430.9930.2370.70.6350.6380.4290.4990.9260.6380.9990.151.00.8160.7630.7030.9680.9490.30.4950.2960.4990.3620.5690.150.2430.5620.7030.150.4260.190.0140.03110.3620.7630.4290.4290.150.9790.01430.7430.7420.9920.610.610.9920.6070.6080.6080.4680.610.3340.6070.610.9980.2220.9980.3340.610.4680.7430.8510.3340.6080.6080.07950.1380.610.2220.3340.7410.7430.3340.6080.001890.7420.7430.4680.4680.3340.8530.7430.9280.7430.4860.1341.01.01.01.01.01.01.01.01.01.00.4851.00.4861.00.4861.01.00.4861.00.4851.00.1340.1340.02421.01.01.00.4860.1340.4860.4861.00.003030.4850.1350.1351.01.01.00.4860.4860.486Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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