deTS Results for Treatment/medication code: fluoxetine

Traits Information:

Trait ID:

2554

20003_1140879540
Treatment/medication code: fluoxetine
UK Biobank (UKBB)
Neale Lab, 2018
# cases = 4140 | # controls = 357001
# SNPs = 11709238 | # genes = 21891
1.014
p (gene) < 0.05:  # TAGs = 1460
p (gene) < 0.01:  # TAGs = 324
p (gene) < 0.001:  # TAGs = 30
p (gene) < 1.0E-4:  # TAGs = 5
p (gene) < 1.0E-5: # TAGs = 1

Manhattan Plot of All SNPs in the GWAS




Manhattan Plot of All Genes in the GWAS


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deTS Enrichment Analysis Using the GTEx Panel


p < 0.05 p < 0.01 p < 0.001 0.3710.5570.6190.3710.1350.3710.4940.3130.1050.04440.2610.4940.1710.3130.3130.4310.1350.3130.6790.6190.5570.3710.7350.6790.4940.1350.3130.4940.9640.2130.1710.9480.9760.0110.08030.4310.6790.7860.4940.7350.9960.830.9280.4940.2130.5570.8690.1170.3970.5260.5260.3970.7740.3970.8680.8680.9330.7740.5260.3970.7740.7740.8680.9710.7740.2820.6570.1170.3970.8680.6570.5260.5260.1170.03840.9330.5260.03840.6570.8680.02010.2820.6570.8680.6570.2820.3970.9970.990.2820.5260.6570.6570.6570.6770.6771.01.01.01.01.01.01.01.01.01.01.01.01.01.01.01.00.6771.01.01.00.6771.01.01.01.00.6770.6770.6770.6771.00.6770.3020.6770.6771.01.00.6770.6771.00.6770.6771.00.6770.6770.302Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel


p < 0.05 p < 0.01 p < 0.001 0.1750.7470.5070.01560.1380.3810.01010.02190.1350.3220.8440.750.4350.6950.8440.8820.6350.2180.08090.3220.1060.170.5070.1350.01520.5720.8010.1750.6950.6950.8780.5070.1380.1050.6310.01030.2180.1060.9920.9560.8440.9120.3220.4430.04880.460.08690.02580.3360.9120.1430.1440.08620.7250.4620.8330.960.7250.4620.9120.4620.3360.2280.4620.4620.005850.9120.460.2270.2280.2280.2280.7250.9860.4590.8330.1450.5950.2270.7240.8330.9610.8330.7250.9860.9610.5970.8331.01.00.6580.01861.00.6581.00.2811.01.01.00.2821.01.01.00.6581.01.00.2821.01.01.00.6580.6580.6580.6580.6584.26E-40.6580.6581.00.6581.01.01.00.6580.6580.6580.08410.6581.00.6580.01861.0Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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