deTS Results for Treatment/medication code: asacol mr 400mg e/c tablet

Traits Information:

Trait ID:

2629

20003_1141188658
Treatment/medication code: asacol mr 400mg e/c tablet
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20003
# cases = 154 | # controls = 360987
# SNPs = 6016972 | # genes = 21861
1.013
p (gene) < 0.05:  # TAGs = 1199
p (gene) < 0.01:  # TAGs = 288
p (gene) < 0.001:  # TAGs = 29
p (gene) < 1.0E-4:  # TAGs = 10
p (gene) < 1.0E-5: # TAGs = 2

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.7140.9270.9910.7140.770.520.6530.4530.8630.820.520.770.520.820.4530.3260.8630.9270.820.04080.5880.05660.1730.07710.520.7140.820.770.820.05660.4530.5880.770.1350.770.6530.5880.2189.03E-41.03E-40.450.04080.1730.770.2690.009070.520.7080.8950.7080.4550.7080.8950.9490.5840.9490.8140.9490.9490.7080.9790.8950.4550.8950.9490.8140.1510.9490.09280.4550.09280.7080.9790.8140.8950.7080.09280.1510.7080.3350.9490.7080.8140.4550.3350.5840.4550.05320.001540.02940.8950.01520.5840.7080.7080.7081.01.01.00.7080.7080.3390.3390.3390.7080.7080.7080.7080.7080.3390.7080.7081.00.3391.01.01.01.00.7080.3390.7081.00.7081.09.48E-40.7080.3391.00.3390.7081.01.01.01.00.3381.24E-40.3391.00.7081.00.339Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.8890.9180.9440.560.4240.6920.1880.1910.2940.920.4920.2420.1470.7510.06440.1940.1160.560.9850.7510.6920.2910.6920.9180.02230.9850.4920.6920.2980.2420.3520.8890.6920.3550.4880.01510.001680.1940.1160.6920.4920.1510.1510.4920.790.6740.9390.790.790.790.6730.6740.6740.790.6760.5480.2010.790.6760.4190.4190.6760.790.8790.9750.2980.8790.6740.02290.9390.5480.4190.3010.4190.5440.5480.5480.5461.00.5460.5480.1290.001080.4190.9910.07740.07740.4190.7070.3371.00.7070.7071.01.00.3370.3370.7071.00.7070.7061.01.01.01.01.00.7070.7070.3380.7061.00.7060.3371.09.31E-40.3380.7070.7071.00.7071.00.7061.00.7060.7070.3389.31E-40.3381.00.3380.1151.0Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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