deTS Results for Treatment/medication code: combivent inhaler

Traits Information:

Trait ID:

2649

20003_1140864734
Treatment/medication code: combivent inhaler
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20003
# cases = 159 | # controls = 360982
# SNPs = 6081087 | # genes = 21864
0.994
p (gene) < 0.05:  # TAGs = 1045
p (gene) < 0.01:  # TAGs = 163
p (gene) < 0.001:  # TAGs = 17
p (gene) < 1.0E-4:  # TAGs = 2
p (gene) < 1.0E-5: # TAGs = 2

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 0.4670.3290.3970.09410.1660.9660.9870.9660.9790.9870.9480.9930.9480.8020.9240.9240.9240.8910.09410.7450.3290.6120.4670.2680.3290.6810.2680.3970.6120.8020.6120.9240.9660.09410.8510.8910.4670.4678.64E-42.8E-40.3930.8510.6120.3290.8020.2680.02320.9770.9770.8120.4820.4820.9210.9770.9210.8120.9210.9210.9770.9210.9770.8120.9210.8120.8120.4820.8120.4820.8120.4820.8120.1910.3190.3190.9210.8120.6570.8120.8120.9210.9210.1910.9970.8120.4820.009430.003580.6560.6570.1910.4820.3190.4820.319Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 0.7120.8260.8280.1010.6430.6430.7690.9750.8720.6430.5710.4960.2810.07320.07320.7740.1780.5710.0360.5710.7740.8710.9850.4930.4930.5710.8740.3520.9750.3520.8240.7120.9750.640.640.3490.00410.7120.1780.4960.4220.9390.2290.960.9740.9730.910.630.630.4520.6280.9730.910.910.4520.630.9090.2920.910.630.910.170.2920.7930.4520.9090.910.910.6290.630.7930.9740.7930.910.7910.631.00.7920.1690.1690.08960.4520.2920.4520.630.4520.910.793Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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