deTS Results for Diagnoses - main ICD10: L82 Seborrhoeic keratosis

Traits Information:

Trait ID:

280

L82
Diagnoses - main ICD10: L82 Seborrhoeic keratosis
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=41202
# cases = 2031 | # controls = 359163
# SNPs = 10512117 | # genes = 21890
1.01
p (gene) < 0.05:  # TAGs = 1299
p (gene) < 0.01:  # TAGs = 284
p (gene) < 0.001:  # TAGs = 44
p (gene) < 1.0E-4:  # TAGs = 15
p (gene) < 1.0E-5: # TAGs = 6

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.8940.4710.6610.8190.4080.2920.5350.2920.4080.2920.1950.3480.3480.4710.3480.3480.4080.5350.4710.9440.1210.8940.09290.7720.5350.2920.5990.1550.9610.8190.6610.5350.4080.5350.9610.5990.240.8940.0270.03780.05090.0270.8940.5990.9930.1950.1210.4390.1320.4390.9030.3140.7070.5750.3140.3140.4390.7070.7070.8190.5750.5750.5750.2110.5750.07760.9840.2110.7070.5750.5750.5750.3140.5750.4390.7070.8190.9840.9030.4390.5750.9030.2110.04280.3140.5750.5750.1310.2110.4390.2110.9030.3140.8190.7080.1160.7080.7080.7080.7080.3390.7080.3390.3391.00.7080.7080.3390.7080.7080.7080.7080.7080.3390.3390.7080.7080.7080.7081.01.00.3390.02960.3391.01.01.01.00.7080.7080.1160.3391.01.00.1150.1161.00.3391.00.3390.708Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.9610.2650.3240.5140.1740.3850.4410.5110.8890.8540.920.580.8060.1050.6440.04260.4490.1740.5140.3240.4490.4410.9830.7020.6410.920.5140.6440.07920.8110.8060.8110.8540.05750.9180.1340.3240.04260.006530.9940.5140.2680.2680.9610.8640.3520.3540.630.4890.2390.6260.9740.9740.630.2390.760.8620.005470.8640.2390.760.9350.2390.630.150.3510.3540.8630.4870.9930.8640.04850.2390.3540.7570.630.3540.01190.7580.6280.8640.9350.760.630.08840.630.3540.4891.00.3180.3191.01.00.1040.6911.01.00.3190.6921.00.6910.1040.6920.3190.6920.6921.01.00.6920.3180.1040.6910.1040.6920.6921.01.01.01.00.6920.6920.1040.6911.00.6920.6921.01.00.3191.00.3191.0Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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