deTS Results for Treatment/medication code: amantadine

Traits Information:

Trait ID:

2816

20003_1140879644
Treatment/medication code: amantadine
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20003
# cases = 113 | # controls = 361028
# SNPs = 5342216 | # genes = 21800
0.985
p (gene) < 0.05:  # TAGs = 1181
p (gene) < 0.01:  # TAGs = 261
p (gene) < 0.001:  # TAGs = 29
p (gene) < 1.0E-4:  # TAGs = 9
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.5140.2610.6480.6480.8980.03760.05260.02630.1280.09720.09720.07220.07220.210.07220.05260.2610.05260.2610.4460.5820.2610.9270.210.210.4460.210.4460.03760.2610.380.7110.210.5820.6480.6480.3180.2610.7680.7110.860.950.7110.4460.7110.9270.8620.4210.7060.2920.4210.8260.2920.5650.8260.7060.7060.5650.5650.2920.9130.7060.5650.8260.2920.06250.4210.9640.1880.9980.1880.8260.1120.2920.9130.9130.7060.4210.7060.4210.1880.5650.8260.4210.5650.7060.5650.9640.8260.8260.5650.7060.9130.2920.2080.2080.5821.01.00.5820.5820.5820.5820.5820.5820.5820.5821.00.5820.5821.01.00.2080.2080.5820.5821.00.5820.05011.00.5821.00.5821.01.00.2080.5821.00.5821.00.5821.01.01.00.5811.00.2080.5821.01.00.208Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.970.440.4430.2030.1210.9960.1980.3720.20.4430.7730.5830.4360.9040.2030.9960.7150.8250.8250.3120.1210.0880.0910.5090.5790.4430.5830.06680.0910.1210.3060.5830.9540.9530.2510.7710.7730.8680.7730.6510.7730.0480.9330.7150.5250.5240.3820.8970.6720.8970.6690.5240.670.9860.5250.8970.7980.9860.2570.9570.2570.9570.8970.6720.09280.5220.8970.7990.9860.5250.2570.02510.053.02E-40.3780.3820.8971.00.7990.670.3820.09280.80.6720.6720.3820.3820.3820.1880.1881.01.00.5591.01.01.01.01.00.5591.00.5581.00.1880.5590.1880.5591.01.00.5590.5580.5591.01.00.1880.1880.5590.1880.5591.00.1881.01.00.5580.1880.5590.5591.00.5590.1880.5590.5591.0Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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