deTS Results for Treatment/medication code: travoprost

Traits Information:

Trait ID:

2827

20003_1141185316
Treatment/medication code: travoprost
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20003
# cases = 141 | # controls = 361000
# SNPs = 5829521 | # genes = 21848
1.007
p (gene) < 0.05:  # TAGs = 1104
p (gene) < 0.01:  # TAGs = 203
p (gene) < 0.001:  # TAGs = 29
p (gene) < 1.0E-4:  # TAGs = 5
p (gene) < 1.0E-5: # TAGs = 2

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.4860.6940.2860.6940.140.9270.8570.6280.6940.3480.6280.6940.8570.3480.5570.4150.230.6280.8570.6280.4150.6940.8570.5570.03970.230.1810.7560.8570.4860.4150.2860.4150.3480.1050.6940.4150.5570.02750.03970.9250.950.6940.4860.7560.2860.9670.6660.6660.1340.5080.6660.8060.5080.2270.6660.6660.5080.5080.9080.3550.1340.2270.5080.6660.9670.5080.6660.3550.8060.2270.2270.5080.9670.5080.8060.5080.8060.9080.9080.5080.5080.5080.6660.6660.002850.007130.9070.8060.2270.6660.8060.9080.6660.6230.6230.2450.6230.6231.01.00.6231.01.01.01.01.01.00.6230.6231.01.01.00.6230.2450.6231.00.6230.2450.6231.00.2450.6231.00.6231.01.01.00.6230.6231.00.6230.6230.6230.2451.00.001990.6231.01.00.623Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.9250.6810.5430.3320.2150.6840.06690.2130.3290.3320.2150.7470.8490.6150.6150.8530.6840.1280.6840.2150.3320.3930.7470.4670.3290.3320.1680.5430.3990.2150.3930.04940.8930.6810.9790.2670.1280.1280.9960.5430.1680.6150.470.06930.7710.8860.6190.3060.1060.1880.1860.7690.1870.05460.7710.4560.6160.8870.3060.9570.1060.4560.6190.9570.6190.1860.7710.1870.8860.4560.3060.9570.8870.8870.7680.6190.7710.8860.9990.6180.05460.02590.7710.6190.7710.8870.6190.6190.5591.00.1881.00.1880.5590.1870.5580.5580.5590.5591.00.5580.5590.5591.00.5590.1880.5591.01.00.1871.01.01.00.5591.01.01.00.5590.5580.5590.5590.04231.01.01.01.01.00.04250.5591.01.00.559Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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