deTS Results for Treatment/medication code: spasmonal 60mg capsule

Traits Information:

Trait ID:

2865

20003_1140865336
Treatment/medication code: spasmonal 60mg capsule
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20003
# cases = 263 | # controls = 360878
# SNPs = 7041838 | # genes = 21882
1.006
p (gene) < 0.05:  # TAGs = 1202
p (gene) < 0.01:  # TAGs = 247
p (gene) < 0.001:  # TAGs = 28
p (gene) < 1.0E-4:  # TAGs = 3
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.6390.6390.7020.760.5040.01690.03550.2520.2020.5720.09270.09270.04980.03550.2020.1590.02470.04980.370.9240.8940.6390.04980.8120.7020.8570.9910.8120.8940.8120.2520.5040.4360.5040.9860.6390.01130.4360.2520.2520.9910.9240.370.5720.7020.5720.5720.6280.4770.07280.07280.01810.2180.1310.3350.07280.2180.1310.2180.1310.1310.2180.3350.001350.07280.3350.4770.8760.3350.03760.3350.7670.3350.8760.8760.9820.8760.3350.9460.4770.6281.00.9460.9460.6280.2180.07280.8750.9460.07280.2180.6280.6280.9460.6420.2640.6420.07530.07530.01580.01580.002550.002550.01580.01580.01580.01580.002550.002550.01580.002550.002550.2640.6420.6421.00.6421.00.6420.6420.2641.01.00.6421.01.00.2641.01.01.01.01.00.2640.2640.6411.01.01.01.01.01.0Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.7840.5930.5970.7270.2130.4570.8290.3210.4530.09710.3890.5270.3820.7270.4570.02540.7840.9570.7840.9890.7840.6570.8330.9570.9890.4570.3250.6640.1670.5970.450.910.3890.8740.3210.210.2130.4570.9980.5270.3250.910.5270.5270.9750.7150.01130.7170.5660.5660.840.9280.9280.5660.9280.5660.09580.8420.05120.0250.4130.8420.5660.5660.7170.840.9750.9750.9280.09730.8420.7170.2770.4130.5630.8420.9990.9280.7150.5650.1710.9280.9940.1710.2770.5660.5660.09730.6020.2250.2250.2250.6020.6020.6010.2250.6010.05750.6021.01.00.6020.6020.2251.00.6020.6020.2250.6020.6011.00.6010.6010.6021.00.6020.2250.6020.6010.6021.00.6011.00.6010.2251.01.01.00.6021.01.01.0Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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