deTS Results for Treatment/medication code: coracten sr 10mg m/r capsule

Traits Information:

Trait ID:

2866

20003_1140861120
Treatment/medication code: coracten sr 10mg m/r capsule
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20003
# cases = 316 | # controls = 360825
# SNPs = 7362960 | # genes = 21883
0.995
p (gene) < 0.05:  # TAGs = 1165
p (gene) < 0.01:  # TAGs = 248
p (gene) < 0.001:  # TAGs = 38
p (gene) < 1.0E-4:  # TAGs = 2
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.3230.3230.9970.9860.9260.2150.2150.1330.1010.1330.1010.2660.1710.450.1710.3230.1710.3230.9770.8970.1710.9260.1010.8610.7110.7110.7680.7110.3230.650.8970.3850.3230.9260.8180.5170.450.040.1710.1710.5130.1710.7110.1010.5170.040.2660.8390.920.8390.920.9680.1240.1240.03710.1240.1240.07010.07010.1240.1240.03710.2040.1240.3111.00.5860.3110.920.2040.9680.7240.3110.5860.920.7240.7240.8390.4430.4430.920.8390.8390.4430.5860.07010.07010.7230.07010.2040.4430.5860.4430.1240.7370.7371.00.3761.01.01.01.01.01.01.01.01.01.01.01.01.01.00.7370.7370.3761.00.3761.00.7370.1380.1380.3760.7370.7370.7370.7370.1380.7370.3760.7370.3760.1380.3760.3761.00.7371.00.3760.3760.3760.138Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.6210.2340.9940.06210.8460.2920.4770.9840.7430.6210.7460.6210.740.03160.3520.6860.7460.1130.2920.9420.80.8820.80.2880.4130.4170.7460.8860.2370.7460.990.9170.4170.01450.03090.4130.06210.9740.04470.6860.6210.9740.2370.1470.3890.5310.6780.6780.9580.1650.8030.8040.9870.90.8050.6780.8030.2630.8050.09610.9580.6780.9580.3890.5330.5290.9580.3870.5310.6780.1650.8050.2630.8050.8990.5330.9580.09540.5310.2620.02630.9870.09610.002280.8051.00.5330.8050.3741.01.00.7351.01.00.7340.3741.01.01.00.7350.7340.3740.7350.7351.01.00.7350.03820.1370.3730.7350.1370.7350.7350.7350.7350.1370.3740.7340.7350.7350.7350.3740.3740.3740.7350.7350.7351.01.01.00.137Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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