deTS Results for Treatment/medication code: glyceryl trinitrate product

Traits Information:

Trait ID:

2909

20003_1141157252
Treatment/medication code: glyceryl trinitrate product
UK Biobank (UKBB)
Neale Lab, 2018
# cases = 338 | # controls = 360803
# SNPs = 7481273 | # genes = 21887
1.02
p (gene) < 0.05:  # TAGs = 1186
p (gene) < 0.01:  # TAGs = 232
p (gene) < 0.001:  # TAGs = 32
p (gene) < 1.0E-4:  # TAGs = 5
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS




Manhattan Plot of All Genes in the GWAS


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deTS Enrichment Analysis Using the GTEx Panel


p < 0.05 p < 0.01 p < 0.001 0.09030.1210.5110.3740.5110.4410.8230.7710.7130.7710.4410.6490.5110.6490.4410.3740.310.2010.5810.5810.8230.5110.02310.7130.8670.9530.7130.3740.5110.9690.8230.3740.7710.6490.7130.4410.2530.1210.5110.5810.5070.04770.6490.7130.5112.98E-50.2530.260.260.70.3930.9730.830.5470.70.70.830.3930.3930.70.5470.5470.830.830.70.260.260.08840.02190.02190.04570.3930.70.3930.260.9220.9220.3930.260.5470.830.70.3930.9220.08840.260.08840.009640.1580.1580.3930.5470.1580.1580.2450.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6230.6231.00.6230.6231.00.6231.01.00.2451.00.2451.00.6231.00.6230.06640.06641.01.00.2450.6231.00.6231.0Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel


p < 0.05 p < 0.01 p < 0.001 0.1130.05990.0610.5740.8220.1920.5670.8650.570.30.4320.8220.4960.1920.1920.0610.1920.1920.9810.8660.9890.4250.1490.9890.9530.2430.4320.5740.7690.6430.08120.4320.1920.7660.4280.9810.5740.8220.30.2430.8660.7090.9320.7690.01810.2360.2370.9690.8140.8140.5170.3650.3650.8140.1410.9120.1390.07710.07710.07710.07710.003180.6770.6770.8140.8120.6770.9990.8130.3670.2370.6770.8140.520.5170.520.8140.07650.5180.5180.3670.9120.07710.1410.8140.9920.9690.6770.2440.6211.00.6220.6221.00.620.6211.00.6220.06581.00.620.6220.2441.00.6220.2441.00.6221.00.620.6221.01.01.01.00.6221.00.6220.06541.00.6221.00.2430.6210.2441.01.00.06580.6221.00.6220.622Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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