deTS Results for Treatment/medication code: dermol 500 lotion

Traits Information:

Trait ID:

2924

20003_1140927320
Treatment/medication code: dermol 500 lotion
UK Biobank (UKBB)
Neale Lab, 2018
# cases = 116 | # controls = 361025
# SNPs = 5402784 | # genes = 21792
1.013
p (gene) < 0.05:  # TAGs = 1119
p (gene) < 0.01:  # TAGs = 282
p (gene) < 0.001:  # TAGs = 30
p (gene) < 1.0E-4:  # TAGs = 3
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS




Manhattan Plot of All Genes in the GWAS


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deTS Enrichment Analysis Using the GTEx Panel


p < 0.05 p < 0.01 p < 0.001 0.850.3440.6860.410.2270.410.3440.410.850.6860.4790.4790.410.2820.6190.2820.2270.410.4790.8890.410.07760.6190.6190.2820.850.9770.850.9210.850.2270.2270.1390.1050.850.1050.9640.7470.8020.6860.4060.550.4790.850.9210.6190.4790.8980.6950.9530.8980.8980.8110.9830.8980.9530.8980.9830.9830.8980.8980.8980.6950.8980.9530.4260.8110.6950.4260.20.5620.4260.9530.9530.8110.9830.8110.8980.5620.3020.5620.6950.8110.9530.4260.6950.6950.30.8980.4260.8980.8110.3020.6950.6420.2641.01.01.01.01.01.00.2640.2641.01.01.01.01.01.00.6421.00.2640.6420.6420.6420.6420.6420.6421.01.01.01.01.01.00.2641.00.6420.6421.01.00.6420.6420.6421.01.01.01.01.00.6421.0Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel


p < 0.05 p < 0.01 p < 0.001 0.4040.0980.1730.07310.8030.8910.4670.6810.40.8510.3370.6170.270.4740.1330.4740.03690.5460.8910.6170.4040.1680.9650.3340.5420.2210.1330.9870.2760.9780.3970.1730.05250.4710.9221.01E-43.41E-40.1730.6170.9230.5460.7470.2210.4740.3740.2550.7750.7750.9410.9930.9770.9770.940.9990.7750.9770.5060.7750.1640.05460.09780.3740.9930.7750.8740.8720.8740.6470.8730.6490.3740.9990.3740.9770.3710.09780.1640.3730.3731.48E-74.03E-80.3740.9410.510.8740.02860.6490.9770.2250.2251.00.6021.00.6021.01.01.01.00.2250.6021.01.00.6020.6021.01.01.01.01.01.00.6021.01.00.2251.00.6021.00.6021.01.01.01.00.6019.88E-111.0E-100.05751.00.6021.00.6021.01.0Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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