deTS Results for Treatment/medication code: syndol tablet

Traits Information:

Trait ID:

3005

20003_1140856342
Treatment/medication code: syndol tablet
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20003
# cases = 289 | # controls = 360852
# SNPs = 7208778 | # genes = 21884
0.988
p (gene) < 0.05:  # TAGs = 1364
p (gene) < 0.01:  # TAGs = 299
p (gene) < 0.001:  # TAGs = 43
p (gene) < 1.0E-4:  # TAGs = 6
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.1460.7180.8970.820.2820.820.9250.9470.4640.5950.9470.9250.7180.7180.9470.7720.5950.820.5950.06380.230.00740.1460.003120.7720.6580.1850.9470.7720.9470.6580.06380.3390.8620.2820.1460.04670.00740.820.820.1820.06380.3390.2820.530.2820.9980.7180.4530.9590.9080.7180.2210.4530.4530.04630.08310.3270.3270.2210.3270.5880.2210.7180.3270.3270.140.2210.0120.9080.02430.140.8280.8280.7180.9080.9850.9080.5880.2210.8280.140.2210.2210.140.9080.9080.3250.2210.5880.8280.2210.4530.9960.7740.1750.7740.7740.4290.4290.4290.7740.1750.4290.4290.4290.4290.4290.7740.7741.00.1750.1750.4290.7740.7741.00.7740.4290.7741.00.7741.01.00.4291.00.4291.00.7740.1750.1750.4291.01.00.4280.4291.00.1751.00.1751.0Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.6180.6140.1940.1530.08930.8790.04640.03380.03380.1180.1530.2420.1480.7930.04830.04830.02420.6810.03450.3550.6810.7880.8790.970.9810.9990.9120.6810.5520.6810.970.3550.4190.7370.150.7370.9710.6810.9810.1180.9370.7930.8790.04830.9480.7930.6740.1110.280.8870.180.1810.2790.1830.6740.1110.180.4010.4010.8870.6740.1830.1830.6740.980.180.9480.9940.980.9990.7940.5370.280.1830.5340.06350.280.6720.007970.980.9940.6740.7940.6740.9480.980.280.06351.00.3741.00.3740.3741.00.7340.3740.3740.7351.00.03820.3730.7350.3741.00.7350.001460.3740.7350.7350.1370.7351.01.01.00.7350.7350.1370.3740.7340.1370.1370.3740.3741.01.00.3741.01.01.00.7350.3740.137Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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